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Tracy M. Handel

University of California San Diego

66H-index
242Paper Count
1.7WCitation Count
Published Papers 93
Publication Date
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Rules of engagement: determinants of chemokine receptor activation and selectivity by CCL27 and CCL28
err2025-09-18
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errOAAI
errMian Huang; Aura F. Celniker; Rezvan Chitsazi; Douglas P. Dyer; Ariane L. Jansma; Irina Kufareva; Catherina L. Salanga; Tracy M. Handel
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Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor
errNATURE
IF48.5
err2025-05-21
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PREAI
errChen, Qiuyan; Schafer, Christopher T.; Mukherjee, Somnath; Wang, Kai; Gustavsson, Martin; Fuller, James R.; Tepper, Katelyn; Lamme, Thomas D.; Aydin, Yasmin; Agrawal, Parth; Terashi, Genki; Yao, Xin-Qiu; Kihara, Daisuke; Kossiakoff, Anthony A.; Handel, Tracy M.
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The dual-function chemokine receptor CCR2 drives migration and chemokine scavenging through distinct mechanisms
err2023-01-31
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errOAAI
errShroka, Thomas M.; Kufareva, Irina; Salanga, Catherina L.; Handel, Tracy M.
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Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors
err2023-01-01
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errOAAI
errGray, Anna L.; Karlsson, Richard; Roberts, Abigail R. E.; Ridley, Amanda J. L.; Pun, Nabina; Khan, Bakhtbilland; Lawless, Craig; Luis, Rafael; Szpakowska, Martyna; Chevigne, Andy; Hughes, Catherine E.; Medina-Ruiz, Laura; Birchenough, Holly L.; Mulholland, Iashia Z.; Salanga, Catherina L.; Yates, Edwin A.; Turnbull, Jeremy E.; Handel, Tracy M.; Graham, Gerard J.; Jowitt, Thomas A.; Schiessl, Ingo; Richter, Ralf P.; Miller, Rebecca L.; Dyer, Douglas P.
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Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias
err2022-07-15
err34
errOAAI
errYen, Yu-Chen; Schafer, Christopher T.; Gustaysson, Martin; Eberle, Stefanie A.; Dominik, Pawel K.; Deneka, Dawid; Zhang, Penglie; Schall, Thomas J.; Kossiakoff, Anthony A.; Tesmer, John J. G.; Handel, Tracy M.
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Anticancer opportunities at every stage of chemokine function
err2021-11-01
err24
errOAAI
errZacarias, Natalia V. Ortiz; Bemelmans, Martijn P.; Handel, Tracy M.; de Visser, Karin E.; Heitman, Laura H.
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Conformational Dynamics of Classical and Atypical GPCRs, CXCR4 and ACKR3, by Single-Molecule FRET
err2021-05-14
err0
PREAI
errSchafer, Christopher; Pauszek, Raymond, III; Gustaysson, Martin; Handel, Tracy; Millar, David
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Cryo-EM Structure of Atypical Chemokine Receptor 3 (ACKR3) in Complex with its Endogenous Ligand CXCL12
err2021-05-14
err0
PREAI
errYen, Yu-Chen; Schafer, Christopher; Gustavsson, Martin; Dominik, Pawel; Kossiakoff, Martin; Handel, Tracy; Tesmer, John
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Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2
err2021-02-18
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errOAAI
errZacarias, Natalia V. Ortiz; Chahal, Kirti K.; Simkova, Tereza; van der Horst, Cas; Zheng, Yi; Inoue, Asuka; Theunissen, Emy; Mallee, Lloyd; van der Es, Daan; Louvel, Julien; IJzerman, Adriaan P.; Handel, Tracy M.; Kufareva, Irina; Heitman, Laura H.
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Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t
err2021-01-01
err21
errOAAI
errWard, Richard J.; Pediani, John D.; Marsango, Sara; Jolly, Richard; Stoneman, Michael R.; Biener, Gabriel; Handel, Tracy M.; Raicu, Valerica; Milligan, Graeme
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Differential activity and selectivity of N-terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors
err2020-05-06
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errOAAI
errJaracz-Ros, Agnieszka; Bernadat, Guillaume; Cutolo, Pasquale; Gallego, Carmen; Gustavsson, Martin; Cecon, Erika; Baleux, Francoise; Kufareva, Irina; Handel, Tracy M.; Bachelerie, Francoise; Levoye, Angelique
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CCR2-Mediated Uptake of Constitutively Produced CCL2: A Mechanism for Regulating Chemokine Levels in the Blood
err2019-12-15
err21
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errZhao, Bin N.; Campbell, James J.; Salanga, Catherina L.; Ertl, Linda S.; Wang, Yu; Yau, Simon; Dang, Ton; Zeng, Yibin; McMahon, Jeffrey P.; Krasinski, Antoni; Zhang, Penglie; Kufareva, Irina; Handel, Tracy M.; Charo, Israel F.; Singh, Rajinder; Schall, Thomas J.
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Leukocyte Adhesion: Reconceptualizing Chemokine Presentation by Glycosaminoglycans
err2019-06-01
err80
errOAAI
errGraham, Gerard J.; Handel, Tracy M.; Proudfoot, Amanda E. I.
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CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry
err2018-12-01
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errOAAI
errVan Hout, Anneleen; Klarenbeek, Alex; Bobkov, Vladimir; Doijen, Jordi; Arimont, Marta; Zhao, Chunxia; Heukers, Raimond; Rimkunas, Rebecca; de Graaf, Chris; Verrips, Theo; van der Woning, Bas; de Haard, Hans; Rucker, Joseph B.; Vermeire, Kurt; Handel, Tracy; Van Loy, Tom; Smit, Martine J.; Schols, Dominique
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Editorial: Chemokines - beyond chemotaxis
err2018-09-01
err1
PREAI
errProudfoot, Amanda E.; Handel, Tracy M.; Graham, Gerry
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A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling
err2018-09-01
err42
errOAAI
errGrimsey, Neil J.; Narala, Rachan; Rada, Cara C.; Mehta, Sohum; Stephens, Bryan S.; Kufareva, Irina; Lapek, John; Gonzalez, David J.; Handel, Tracy M.; Zhang, Jin; Trejo, JoAnn
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Intracellular Receptor Modulation: Novel Approach to Target GPCRs
err2018-06-01
err44
errOAAI
errZacarias, Natalia V. Ortiz; Lenselink, Eelke B.; IJzerman, Adriaan P.; Handel, Tracy M.; Heitman, Laura H.
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