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SARS-CoV-2 conjugate vaccine elicits robust immune responses that can protect against evolving variants. Carroll, Melanie; Fox, Heather B.; Tran, Anh; Chellappan, Gowri; Rojas, Leonardov; Karengil, Geetha; Karandish, Fataneh; Langston, John W.; Fall, Brent M.; Whalen, Mary M.; Mccluskie, Michael J.; Durocher, Yves; Datta, Anup; Kapre, Subhash, V; Olave, Ivan A. Share Save
Development of a Scalable Synthesis of Casdatifan (AB521), a Potent, Selective, Clinical-Stage Inhibitor of HIF-2α Hardman, Clayton; Mailyan, Artur K.; Mata, Guillaume; Beatty, Joel W.; Drew, Samuel L.; Fournier, Jeremy; Kalisiak, Jaroslaw; Rosen, Brandon R.; Epplin, Matthew; Gal, Balint; Yu, Kai; Wang, Zhang; Haelsig, Karl; Tran, Anh; Leleti, Manmohan R.; Powers, Jay P.; Lawson, Kenneth V. Share Save
Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals Aljehani, Najwa D.; Tamming, Levi; Khan, Muhammad Yasir; Abdulal, Rwaa H.; Alfaleh, Mohamed A.; Ghazwani, Aishah; Helal, Asalah; Alsulaiman, Reem M.; Sanki, Mohammad A.; Alluhaybi, Khalid; Sukareh, Farah Ayman; Alharbi, Rahaf H.; Alyami, Faris H.; ElAssouli, M-Zaki; Shebbo, Salima; Abdulaal, Wesam H.; Algaissi, Abdullah; Mahmoud, Ahmad Bakur; Basabrain, Mohammad; Duque, Diana; Bavananthasivam, Jegarubee; Chen, Wangxue; Wang, Lisheng; Sauve, Simon; Abujamel, Turki S.; Altorki, Tarfa; Alhabbab, Rowa; Tran, Anh; Li, Xuguang; Hashem, Anwar M. Share Save
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Effectiveness of VSV vectored SARS-CoV-2 spike when administered through intranasal, intramuscular or a combination of both Beitari, Saina; Agbayani, Gerard; Hewitt, Melissa; Duque, Diana; Bavananthasivam, Jegarubee; Sandhu, Jagdeep K.; Akache, Bassel; Hadzisejdic, Ita; Tran, Anh Share Save
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Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells Alpuche-Lazcano, Sergio P.; Stuible, Matthew; Akache, Bassel; Tran, Anh; Kelly, John; Hrapovic, Sabahudin; Robotham, Anna; Haqqani, Arsalan; Star, Alexandra; Renner, Tyler M.; Blouin, Julie; Maltais, Jean-Sebastien; Cass, Brian; Cui, Kai; Cho, Jae-Young; Wang, Xinyu; Zoubchenok, Daria; Dudani, Renu; Duque, Diana; Mccluskie, Michael J.; Durocher, Yves Share Save
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Multivalent IgM scaffold enhances the therapeutic potential of variant-agnostic ACE2 decoys against SARS-CoV-2 Verstraete, Meghan M.; Heinkel, Florian; Li, Janessa; Cao, Siran; Tran, Anh; Halverson, Elizabeth C.; Gene, Robert; Stangle, Elizabeth; Silva-Moreno, Begonia; Arrafi, Sifa; Bavananthasivam, Jegarubee; Fung, Madeline; Eji-Lasisi, Mariam; Masterman, Stephanie; Xanthoudakis, Steve; Dixit, Surjit; Babcook, John; Clavette, Brandon; Fogg, Mark; Escobar-Cabrera, Eric Share Save
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Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models Rossotti, Martin A.; van Faassen, Henk; Tran, Anh T.; Sheff, Joey; Sandhu, Jagdeep K.; Duque, Diana; Hewitt, Melissa; Wen, Xiaoxue; Bavananthasivam, Jegarubee; Beitari, Saina; Matte, Kevin; Laroche, Genevieve; Giguere, Patrick M.; Gervais, Christian; Stuible, Matthew; Guimond, Julie; Perret, Sylvie; Hussack, Greg; Langlois, Marc-Andre; Durocher, Yves; Tanha, Jamshid Share Save
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Intranasal immunization with a proteosome-adjuvanted SARS-CoV-2 spike protein-based vaccine is immunogenic and efficacious in mice and hamsters Stark, Felicity C.; Akache, Bassel; Deschatelets, Lise; Anh Tran; Stuible, Matthew; Durocher, Yves; McCluskie, Michael J.; Agbayani, Gerard; Dudani, Renu; Harrison, Blair A.; Renner, Tyler M.; Makinen, Shawn R.; Bavananthasivam, Jegarubee; Duque, Diana; Gagne, Martin; Zimmermann, Joseph; Zarley, C. David; Cochrane, Terrence R.; Handfield, Martin Share Save
DNA Based Vaccine Expressing SARS-CoV-2 Spike-CD40L Fusion Protein Confers Protection Against Challenge in a Syrian Hamster Model Tamming, Levi A.; Duque, Diana; Anh Tran; Zhang, Wanyue; Pfeifle, Annabelle; Laryea, Emmanuel; Wu, Jianguo; Raman, Sathya N. Thulasi; Gravel, Caroline; Russell, Marsha S.; Hashem, Anwar M.; Alsulaiman, Reem M.; Alhabbab, Rowa Y.; Gao, Jun; Safronetz, David; Cao, Jingxin; Wang, Lisheng; Chen, Wangxue; Johnston, Michael J. W.; Sauve, Simon; Rosu-Myles, Michael; Li, Xuguang Share Save
Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant Akache, Bassel; Renner, Tyler M.; Tran, Anh; Deschatelets, Lise; Dudani, Renu; Harrison, Blair A.; Duque, Diana; Haukenfrers, Julie; Rossotti, Martin A.; Gaudreault, Francis; Hemraz, Usha D.; Lam, Edmond; Regnier, Sophie; Chen, Wangxue; Gervais, Christian; Stuible, Matthew; Krishnan, Lakshmi; Durocher, Yves; McCluskie, Michael J. Share Save
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Development of a Scalable Method for Manufacturing the Central Core of CD73 Inhibitor AB680 Fournier, Jeremy; Yan, Xuelei; Tran, Anh T.; Grange, Rebecca L.; Jacob, Steven D.; Kalisiak, Jaroslaw; Lawson, Kenneth, V; Connor, Eric F.; Leleti, Manmohan R.; Powers, Jay P. Share Save
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Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73 Beatty, Joel W.; Lindsey, Erick A.; Thomas-Tran, Rhiannon; Debien, Laurent; Mandal, Debashis; Jeffrey, Jenna L.; Tran, Anh T.; Fournier, Jeremy; Jacob, Steven D.; Yan, Xuelei; Drew, Samuel L.; Ginn, Elaine; Chen, Ada; Pham, Amber T.; Zhao, Sharon; Jin, Lixia; Young, Stephen W.; Walker, Nigel P.; Leleti, Manmohan Reddy; Moschuetz, Susanne; Straeter, Norbert; Powers, Jay P.; Lawson, Kenneth, V Share Save
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