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Robert J. Linhardt

Department of Chemistry and Chemical Biology

123H-index
1.6KPaper Count
6.8WCitation Count
Published Papers 215
Publication Date
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Novel regulators of heparan sulfate proteoglycans modulate cellular uptake of α-synuclein fibrils
errCommunications Biology
IF5.1
err2025-10-06
err0
errOAAI
errBenoît Vanderperre; Amitha Muraleedharan; Marie-France Dorion; Frédérique Larroquette; Esther Del Cid Pellitero; Nishani Rajakulendran; Carol X.-Q. Chen; Roxanne Larivière; Charlotte Michaud-Tardif; Thomas Goiran; Rony Chidiac; Damien Lipuma; Graham MacLeod; Rhalena Thomas; Zhangjie Wang; Wolfgang E. Reintsch; Wen Luo; Irina Shlaifer; Fuming Zhang; Ke Xia; Zachary Steinhart; Robert J. Linhardt; Jean-François Trempe; Jian Liu; Thomas M. Durcan; Stephane Angers; Edward A. Fon
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errSave
Astrocyte Extracellular Matrix Modulates Neuronal Dendritic Development
errGLIA
IF5.1
err2025-04-07
err0
PREAI
errJoel G. Hashimoto; Nicholas Margolies; Xiaolu Zhang; Joshua Karpf; Yuefan Song; Natalie Gorham; Brett A. Davis; Fuming Zhang; Robert J. Linhardt
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Heparan sulfate regulates the fate decisions of human pluripotent stem cells
errSTEM CELL REPORTS
IF5.1
err2025-01-01
err0
errOAAI
errSyangtan, Deepsing; Al Mahbuba, Deena; Masuko, Sayaka; Li, Qiao; Elton, Andrew C.; Zaltsman, Yefim; Wrighton, Paul J.; Xia, Ke; Han, Xiaorui; Ouyang, Yilan; Zhang, Fuming; Linhardt, Robert J.; Kiessling, Laura L.
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Physicochemical properties, non-volatile flavor components and antioxidant activity analysis of Ganoderma lucidum (Curtis) P. Karst. extracts dried by different methods
errFOOD BIOSCIENCE
IF5.9
err2024-12-01
err0
PREAI
errZhang, Gaopeng; Pan, Yuemin; Wang, Yaning; Ye, Songmei; Zhang, Fuming; Linhardt, Robert J.; Zhang, Anqiang
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Towards Cell-Permeable Hepatitis B Virus Core Protein Variants as Potential Antiviral Agents
errMICROORGANISMS
IF4.2
err2024-08-28
err0
errOAAI
errBendahmane, Sanaa; Follo, Marie; Zhang, Fuming; Linhardt, Robert J.
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errSave
Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis
errCARBOHYDRATE POLYMERS
IF12.5
err2024-08-01
err3
PREAI
errSong, Yuefan; Singh, Amit; Feroz, Maisha M.; Xu, Shirley; Zhang, Fuming; Jin, Weihua; Kumar, Ambrish; Azadi, Parastoo; Metzger, Dennis W.; Linhardt, Robert J.; Dordick, Jonathan S.
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Marine-Derived Sulfated Glycans Inhibit the Interaction of Heparin with Adhesion Proteins of Mycoplasma pneumoniae
errMARINE DRUGS
IF5.4
err2024-05-20
err0
errOAAI
errYang, Jiyuan; Song, Yuefan; Xia, Ke; Pomin, Vitor H.; Wang, Chunyu; Qiao, Mingqiang; Linhardt, Robert J.; Dordick, Jonathan S.; Zhang, Fuming
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errSave
Synthesis of bioengineered heparin chemically and biologically similar to porcine- derived products and convertible to low MW heparin
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-03-18
err5
errOAAI
errDouaisi, Marc; Paskaleva, Elena E.; Fu, Li; Grover, Navdeep; McManaman, Charity L.; Varghese, Sony; Brodfuehrer, Paul R.; Gibson, James M.; de Joode, Ian; Xia, Ke; Brier, Matthew I.; Simmons, Trevor J.; Datta, Payel; Zhang, Fuming; Onishi, Akihiro; Hirakane, Makoto; Mori, Daisuke; Linhardt, Robert J.; Dordick, Jonathan S.
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errSave
Heparin Specifically Inhibits CRISPR/Cas12 Activation, Enabling Ultrasensitive Heparin Detection and Gene Editing Regulation
errANALYTICAL CHEMISTRY
IF6.7
err2024-02-22
err5
PREAI
errCao, Min; Bian, Xinlan; Ji, Zhirun; Sohail, Muhammad; Zhang, Fuming; Linhardt, Robert J.; Li, Bingzhi; Zhang, Xing
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errSave
Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin
errVIRUSES-BASEL
IF3.5
err2024-02-02
err5
errOAAI
errYang, Jiyuan; Song, Yuefan; Jin, Weihua; Xia, Ke; Burnett, Grace C.; Qiao, Wanjin; Bates, John T.; Pomin, Vitor H.; Wang, Chunyu; Qiao, Mingqiang; Linhardt, Robert J.; Dordick, Jonathan S.; Zhang, Fuming
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errSave
β-Glucosidase on clay minerals: Structure and function in the synthesis of octyl glucoside
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2024-01-01
err2
PREAI
errWang, Feng; Wang, Haohao; Kang, Kang; Zhang, Xuan; Fraser, Keith; Zhang, Fuming; Linhardt, Robert J.
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errSave
New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry
errJOURNAL OF THROMBOSIS AND HAEMOSTASIS
IF5
err2023-12-01
err5
errOAAI
errShi, Deling; Zhao, Huimin; Bu, Changkai; Fraser, Keith; Wang, Haoran; Dordick, Jonathan S.; Linhardt, Robert J.; Zhang, Fuming; Shi, Feng; Chi, Lianli
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errSave
Structure and microbial-modulating evaluation of a sulfhydryl-modified pectin
errFOOD HYDROCOLLOIDS
IF12.4
err2023-11-01
err1
PREAI
errHou, Lijuan; Yu, Chengxiao; Zhang, Laiming; Zhang, Fuming; Linhardt, Robert J.; Chen, Shiguo; Ye, Xingqian; Hou, Zhiqiang
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errSave
Structural characterization of an antioxidant polysaccharide isolated from the fruiting bodies of Lyophyllum decastes
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2023-08-01
err11
PREAI
errZhang, Gaopeng; Wang, Yaning; Qin, Chunqing; Ye, Songmei; Zhang, Fuming; Linhardt, Robert J.; Zhang, Anqiang
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errSave
The Sea Cucumber Thyonella gemmata Contains a Low Anticoagulant Sulfated Fucan with High Anti-SARS-CoV-2 Actions against Wild-Type and Delta Variants
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2023-06-12
err3
errOAAI
errDwivedi, Rohini; Farrag, Marwa; Sharma, Poonam; Shi, Deling; Shami, Anter A.; Misra, Sandeep K.; Ray, Priya; Shukla, Jayanti; Zhang, Fuming; Linhardt, Robert J.; Sharp, Joshua S.; Tandon, Ritesh; Pomin, Vitor H.
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Extraction, structure and bioactivities of polysaccharides from Sanghuangporus spp.: A review
errFOOD BIOSCIENCE
IF5.9
err2023-06-01
err4
PREAI
errLin, Genglan; Li, Yanying; Chen, Xiaohua; Zhang, Fuming; Linhardt, Robert J.; Zhang, Anqiang
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errSave
Structure, anti-SARS-CoV-2, and anticoagulant effects of two sulfated galactans from the red alga Botryocladia occidentalis
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2023-05-01
err8
errOAAI
errMaurya, Antim K.; Sharma, Poonam; Samanta, Priyanka; Shami, Anter A.; Misra, Sandeep K.; Zhang, Fuming; Thara, Reena; Kumar, Deepak; Shi, Deling; Linhardt, Robert J.; Sharp, Joshua S.; Doerksen, Robert J.; Tandon, Ritesh; Pomin, Vitor H.
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errSave
Sulfated fuco-manno-glucuronogalactan alleviates pancreatic beta cell senescence via PI3K/AKT/FoxO1 pathway
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2023-05-01
err3
PREAI
errZhang, Wenjing; Wu, Nan; Wang, Hong; Mao, Genxiang; Yan, Xiaojun; Zhang, Fuming; Linhardt, Robert J.; Jin, Weihua; Zhou, Jiaqiang
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errSave
Apolipoprotein E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2023-04-28
err14
errOAAI
errMah, Dylan; Zhu, Yanan; Su, Guowei; Zhao, Jing; Canning, Ashely; Gibson, James; Song, Xuehong; Stancanelli, Eduardo; Xu, Yongmei; Zhang, Fuming; Linhardt, Robert J.; Liu, Jian; Wang, Lianchun; Wang, Chunyu
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SPR Sensor-Based Analysis of the Inhibition of Marine Sulfated Glycans on Interactions between Monkeypox Virus Proteins and Glycosaminoglycans
errMARINE DRUGS
IF5.4
err2023-04-25
err8
errOAAI
errHe, Peng; Shi, Deling; Li, Yunran; Xia, Ke; Kim, Seon Beom; Dwivedi, Rohini; Farrag, Marwa; Pomin, Vitor H. H.; Linhardt, Robert J. J.; Dordick, Jonathan S. S.; Zhang, Fuming
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Research Directions

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Co-authors
Cooperation Journals
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T
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田
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H-index: 145 · Papers: 1.3K
L
Leonard I. Zon
H-index: 135 · Papers: 854
A
Ajit Varki
H-index: 130 · Papers: 757
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