Not logged in Assessing Hybridization-Dependent Off-Target Risk for Therapeutic Oligonucleotides: Updated Industry Recommendations Andersson, Patrik; Burel, Sebastien A.; Estrella, Heather; Foy, Jeffrey; Hagedorn, Peter H.; Harper, Tod A.; Henry, Scott P.; Hoflack, Jean-Christophe; Holgersen, Erle M.; Levin, Arthur A.; Morrison, Eliot; Pavlicek, Adam; Penso-Dolfin, Luca; Saxena, Utsav Share Save
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Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor Hallin, Jill; Bowcut, Vickie; Calinisan, Andrew; Briere, David M.; Hargis, Lauren; Engstrom, Lars D.; Laguer, Jade; Medwid, James; Vanderpool, Darin; Lifset, Ella; Trinh, David; Hoffman, Natalie; Wang, Xiaolun; Lawson, J. David; Gunn, Robin J.; Smith, Christopher R.; Thomas, Nicole C.; Martinson, Matthew; Bergstrom, Alex; Sullivan, Francis; Bouhana, Karyn; Winski, Shannon; He, Leo; Fernandez-Banet, Julio; Pavlicek, Adam; Haling, Jacob R.; Rahbaek, Lisa; Marx, Matthew A.; Olson, Peter; Christensen, James G. Share Save
The KRASG12C Inhibitor MRTX849 Reconditions the Tumor Immune Microenvironment and Sensitizes Tumors to Checkpoint Inhibitor Therapy Briere, David M.; Li, Shuai; Calinisan, Andrew; Sudhakar, Niranjan; Aranda, Ruth; Hargis, Lauren; Peng, David H.; Deng, Jiehui; Engstrom, Lars D.; Hallin, Jill; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Wong, Kwok-Kin; Christensen, James G.; Olson, Peter Share Save
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The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients Hallin, Jill; Engstrom, Lars D.; Hargis, Lauren; Calinisan, Andrew; Aranda, Ruth; Briere, David M.; Sudhakar, Niranjan; Bowcut, Vickie; Baer, Brian R.; Ballard, Joshua A.; Burkard, Michael R.; Fell, Jay B.; Fischer, John P.; Vigers, Guy P.; Xue, Yaohua; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Velastagui, Karen; Chao, Richard C.; Barton, Jeremy; Pierobon, Mariaelena; Baldelli, Elisa; Patricoin, Emanuel F., III; Cassidy, Douglas P.; Marx, Matthew A.; Rybkin, Igor I.; Johnson, Melissa L.; Ou, Sai-Hong Ignatius; Lito, Piro; Papadopoulos, Kyriakos P.; Janne, Pasi A.; Olson, Peter; Christensen, James G. Share Save
The KRASG12C inhibitor MRTX849 reconditions the tumor immune microenvironment and leads to durable complete responses in combination with anti-PD-1 therapy in a syngeneic mouse model Briere, David M.; Calinisan, Andrew; Aranda, Ruth; Sudhakar, Niranjan; Hargis, Lauren; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Engstrom, Lars D.; Hallin, Jill; Christensen, James G.; Olson, Peter Share Save
Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease Lee, Edmund C.; Valencia, Tania; Allerson, Charles; Schairer, Annelie; Flaten, Andrea; Yheskel, Matanel; Kersjes, Kara; Li, Jian; Gatto, Sole; Takhar, Mandeep; Lockton, Steven; Pavlicek, Adam; Kim, Michael; Chu, Tiffany; Soriano, Randy; Davis, Scott; Androsavich, John R.; Sarwary, Salma; Owen, Tate; Kaplan, Julia; Liu, Kai; Jang, Graham; Neben, Steven; Bentley, Philip; Wright, Timothy; Patel, Vishal Share Save
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth Huang, Xinqiang; Magnus, Jill; Kaimal, Vivek; Karmali, Priya; Li, Jian; Walls, Marlena; Prudente, Rene; Sung, Eric; Sorourian, Mehran; Lee, Robin; Davis, Scott; Yang, Xia; Estrella, Heather; Lee, Edmund C.; Chau, B. Nelson; Pavlicek, Adam; Zabludoff, Sonya Share Save
Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial van der Ree, Meike H.; de Vree, J. Marleen; Stelma, Femke; Willemse, Sophie; van der Valk, Marc; Rietdijk, Svend; Molenkamp, Richard; Schinkel, Janke; van Nuenen, Ad C.; Beuers, Ulrich; Hadi, Salah; Harbers, Marten; van der Veer, Eva; Liu, Kai; Grundy, John; Patick, Amy K.; Pavlicek, Adam; Blem, Jacqueline; Huang, Michael; Grint, Paul; Neben, Steven; Gibson, Neil W.; Kootstra, Neeltje A.; Reesink, Hendrik W. Share Save
SEQUENCE ANALYSIS FOR RESISTANCE MONITORING FOLLOWING A SINGLE DOSE OF RG-101, AN ANTI-MIR TARGETING MICRORNA-122, IN CHRONIC HEPATITIS C PATIENTS van der Ree, M. H.; Stelma, F.; de Vree, J. M. L.; Willemse, S. B.; van der Valk, M.; van Nuenen, Ad. C.; Patick, A.; Grint, P.; Neben, S.; Pavlicek, A.; van der Veer, E.; Kootstra, N. A.; Reesink, H. W. Share Save
Anti-miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network Deregulation Wagenaar, Timothy R.; Zabludoff, Sonya; Ahn, Sung-Min; Allerson, Charles; Arlt, Heike; Baffa, Raffaele; Cao, Hui; Davis, Scott; Garcia-Echeverria, Carlos; Gaur, Rajula; Huang, Shih-Min A.; Jiang, Lan; Kim, Deokhoon; Metz-Weidmann, Christiane; Pavlicek, Adam; Pollard, Jack; Reeves, Jason; Rocnik, Jennifer L.; Scheidler, Sabine; Shi, Chaomei; Sun, Fangxian; Tolstykh, Tatiana; Weber, William; Winter, Christopher; Yu, Eunsil; Yu, Qunyan; Zheng, Gang; Wiederschain, Dmitri Share Save
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miR-221: A potential therapeutic target for hepatocellular carcinoma Lee, Edmund C.; Xu, Jessica; Vincent, Thomas; Chen, Jie; Nelson, Michael; Huang, Xinqiang; Marcusson, Eric; Androsavich, John; Davis, Scott; Pavlicek, Adam; Gibson, Neil; Zabludoff, Sonya Share Save
Targeting miR-21 in hepatocellular carcinoma Zabludoff, Sonya; Wagenaar, Timothy; Adrian, Francisco; Allerson, Charles; Arlt, Heike; Baffa, Raffaele; Bhat, Bal; Cao, Hui; Davis, Scott; Garcia-Echeverria, Carlos; Heermeier, Kathrin; Huang, Shih-Min; Jiang, Lan; Marcusson, Eric; Metz-Weidmann, Christiane; Pavlicek, Adam; Pollard, Jack; Rocnik, Jennifer; Scheidler, Sabine; Shi, Chaomei; Sun, Fangxian; Tolstykh, Tatiana; Yu, Qunyan; Zheng, Gang; Wiederschain, Dmitri Share Save
Test of Four Colon Cancer Risk-Scores in Formalin Fixed Paraffin Embedded Microarray Gene Expression Data Di Narzo, Antonio F.; Tejpar, Sabine; Rossi, Simona; Yan, Pu; Popovici, Vlad; Wirapati, Pratyaksha; Budinska, Eva; Xie, Tao; Estrella, Heather; Pavlicek, Adam; Mao, Mao; Martin, Eric; Scott, Weinrich; Bosman, Fred T.; Roth, Arnaud; Delorenzi, Mauro Share Save
Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871) Pavlicek, Adam; Lira, Maruja E.; Lee, Nathan V.; Ching, Keith A.; Ye, Jingjing; Cao, Joan; Garza, Scott J.; Hook, Kenneth E.; Ozeck, Mark; Shi, Stephanie T.; Yuan, Jing; Zheng, Xianxian; Rejto, Paul A.; Kan, Julie L. C.; Christensen, James G. Share Save
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