Not logged in A multilineage screen identifies actionable synthetic lethal interactions in human cancers Fong, Samson H.; Kuenzi, Brent M.; Mattson, Nicole M.; Lee, John; Sanchez, Kyle; Bojorquez-Gomez, Ana; Ford, Kyle; Munson, Brenton P.; Licon, Katherine; Bergendahl, Sarah; Shen, John Paul; Kreisberg, Jason F.; Mali, Prashant; Hager, Jeffrey H.; White, Michael A.; Ideker, Trey Share Save
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Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome Wang, Tina; Ma, Jianzhu; Hogan, Andrew N.; Fong, Samson; Licon, Katherine; Tsui, Brian; Kreisberg, Jason F.; Adams, Peter D.; Carvunis, Anne-Ruxandra; Bannasch, Danika L.; Ostrander, Elaine A.; Ideker, Trey Share Save
High-throughput combinatorial CRISPR-Cas9 gene knockout reveals most genetic interactions are context dependent Shen, John Paul; Zhao, Dongxin; Munson, Brenton; Birmingham, Amanda; Sasik, Roman; Bojorquez-Gomez, Ana; Licon, Katherine; Klepper, Kristin; Beckett, Alex; Sanchez, Kyle Salinas; Mali, Prashant; Ideker, Trey Share Save
Disruption of NSD1 in Head and Neck Cancer Promotes Favorable Chemotherapeutic Responses Linked to Hypomethylation Bui, Nam; Huang, Justin K.; Bojorquez-Gomez, Ana; Licon, Katherine; Sanchez, Kyle S.; Tang, Sean N.; Beckett, Alex N.; Wang, Tina; Zhang, Wei; Shen, John Paul; Kreisberg, Jason F.; Ideker, Trey Share Save
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression Zhang, Wei; Bojorquez-Gomez, Ana; Velez, Daniel Ortiz; Xu, Guorong; Sanchez, Kyle S.; Shen, John Paul; Chen, Kevin; Licon, Katherine; Melton, Collin; Olson, Katrina M.; Yu, Michael Ku; Huang, Justin K.; Carter, Hannah; Farley, Emma K.; Snyder, Michael; Fraley, Stephanie I.; Kreisberg, Jason F.; Ideker, Trey Share Save
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Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions Shen, John Paul; Zhao, Dongxin; Sasik, Roman; Luebeck, Jens; Birmingham, Amanda; Bojorquez-Gomez, Ana; Licon, Katherine; Klepper, Kristin; Pekin, Daniel; Beckett, Alex N.; Sanchez, Kyle Salinas; Thomas, Alex; Kuo, Chih-Chung; Du, Dan; Roguev, Assen; Lewis, Nathan E.; Chang, Aaron N.; Kreisberg, Jason F.; Krogan, Nevan; Qi, Lei; Ideker, Trey; Mali, Prashant Share Save
Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy Kramer, Michael H.; Farre, Jean-Claude; Mitra, Koyel; Yu, Michael Ku; Ono, Keiichiro; Demchak, Barry; Licon, Katherine; Flagg, Mitchell; Balakrishnan, Rama; Cherry, J. Michael; Subramani, Suresh; Ideker, Trey Share Save
A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy Srivas, Rohith; Shen, John Paul; Yang, Chih Cheng; Sun, Su Ming; Li, Jianfeng; Gross, Andrew M.; Jensen, James; Licon, Katherine; Bojorquez-Gomez, Ana; Klepper, Kristin; Huang, Justin; Pekin, Daniel; Xu, Jia L.; Yeerna, Huwate; Sivaganesh, Vignesh; Kollenstart, Leonie; van Attikum, Haico; Aza-Blanc, Pedro; Sobol, Robert W.; Ideker, Trey Share Save
Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA Gross, Andrew M.; Jaeger, Philipp A.; Kreisberg, Jason F.; Licon, Katherine; Jepsen, Kristen L.; Khosroheidari, Mahdieh; Morsey, Brenda M.; Swindells, Susan; Shen, Hui; Ng, Cherie T.; Flagg, Ken; Chen, Daniel; Zhang, Kang; Fox, Howard S.; Ideker, Trey Share Save
Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems Yu, Michael Ku; Kramer, Michael; Dutkowski, Janusz; Srivas, Rohith; Licon, Katherine; Kreisberg, Jason F.; Ng, Cherie T.; Krogan, Nevan; Sharan, Roded; Ideker, Trey Share Save
RAD17 loss of function is synthetically lethal with the checkpoint kinase inhibitors AZD7762 or MK-1775 Shen, John Paul; Srivas, Rohith; Bojorquez-Gomez, Ana; Licon, Katherine; Sivaganesh, Vignesh; Xu, Jia L.; Yeerna, Huwate; Gross, Andrew; Li, Jian Feng; Sobol, Robert; Ideker, Trey Share Save
High-throughput synthetic lethal interaction screening in model organisms as a strategy for the identification of novel therapeutic targets in cancer Srivas, Rohith; Shen, John Paul; Li, Jian Feng; Licon, Katherine; Wang, Ze Zhong; Bojoquez-Gomez, Ana; Xu, Lucy; Gross, Andrew; Bean, Gordon; Sobol, Robert; Ideker, Trey Share Save
A UV-Induced Genetic Network Links the RSC Complex to Nucleotide Excision Repair and Shows Dose-Dependent Rewiring Srivas, Rohith; Costelloe, Thomas; Carvunis, Anne-Ruxandra; Sarkar, Sovan; Malta, Erik; Sun, Su Ming; Pool, Marijke; Licon, Katherine; van Welsem, Tibor; van Leeuwen, Fred; McHugh, Peter J.; van Attikum, Haico; Ideker, Trey Share Save
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