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Nikolaus Heveker

universite de montreal

39H-index
121Paper Count
4.9KCitation Count
Published Papers 46
Publication Date
The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment
errCELLS
IF5.2
err2019-06-18
err69
errOAAI
errReynders, Nathan; Abboud, Dayana; Baragli, Alessandra; Noman, Muhammad Zaeem; Rogister, Bernard; Niclou, Simone P.; Heveker, Nikolaus; Janji, Bassam; Hanson, Julien; Szpakowska, Martyna; Chevigne, Andy
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Biased antagonism of CXCR4 avoids antagonist tolerance
err2018-10-16
err35
errOAAI
errHitchinson, Ben; Eby, Jonathan M.; Gao, Xianlong; Guite-Vinet, Francois; Ziarek, Joshua J.; Abdelkarim, Hazem; Lee, Youngshim; Okamoto, Yukari; Shikano, Sojin; Majetschak, Matthias; Heveker, Nikolaus; Volkman, Brian F.; Tarasova, Nadya I.; Gaponenko, Vadim
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Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice
err2018-06-01
err52
errOAAI
errFougerat, Anne; Pan, Xuefang; Smutova, Victoria; Heveker, Nikolaus; Cairo, Christopher W.; Issad, Tarik; Larrivee, Bruno; Medin, Jeffrey A.; Pshezhetsky, Alexey V.
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Structure-Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3)
err2018-04-02
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PREAI
errSekiguchi, Haruka; Kuroyanagi, Tomoko; Rhainds, David; Kobayashi, Kazuya; Kobayashi, Yuka; Ohno, Hiroaki; Heveker, Nikolaus; Akaji, Kenichi; Fujii, Nobutaka; Oishi, Shinya
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Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3
err2018-03-23
err55
errOAAI
errSzpakowska, Martyna; Nevins, Amanda M.; Meyrath, Max; Rhainds, David; D'huys, Thomas; Guite-Vinet, Francois; Dupuis, Nadine; Gauthier, Pierre-Arnaud; Counson, Manuel; Kleist, Andrew; St-Onge, Genevieve; Hanson, Julien; Schols, Dominique; Volkman, Brian F.; Heveker, Nikolaus; Chevigne, Andy
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Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging
err2018-01-01
err36
errOAAI
errMontpas, Nicolas; St-Onge, Genevieve; Nama, Nassr; Rhainds, David; Benredjem, Besma; Girard, Melanie; Hickson, Gilles; Pons, Veronique; Heveker, Nikolaus
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Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation
err2017-03-21
err79
errOAAI
errZiarek, Joshua J.; Kleist, Andrew B.; London, Nir; Raveh, Barak; Montpas, Nicolas; Bonneterre, Julien; St-Onge, Genevieve; DiCosmo-Ponticello, Crystal J.; Koplinski, Chad A.; Roy, Ishan; Stephens, Bryan; Thelen, Sylvia; Veldkamp, Christopher T.; Coffman, Frederick D.; Cohen, Marion C.; Dwinell, Michael B.; Thelen, Marcus; Peterson, Francis C.; Heveker, Nikolaus; Volkman, Brian F.
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Mutational Analysis of Atypical Chemokine Receptor 3 (ACKR3/CXCR7) Interaction with Its Chemokine Ligands CXCL11 and CXCL12
err2017-01-01
err44
errOAAI
errBenredjem, Besma; Girard, Melanie; Rhainds, David; St-Onge, Genevieve; Heveker, Nikolaus
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Structure-Activity Relationship and Signaling of New Chimeric CXCR4 Agonists
err2016-08-11
err8
PREAI
errMona, Christine E.; Besserer-Offroy, Elie; Cabana, Jerome; Lefrancois, Marilou; Boulais, Philip E.; Lefebvre, Marie-Reine; Leduc, Richard; Lavigne, Pierre; Heveker, Nikolaus; Marsault, Eric; Escher, Emanuel
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Development of Novel CXC Chemokine Receptor 7 (CXCR7) Ligands: Selectivity Switch from CXCR4 Antagonists with a Cyclic Pentapeptide Scaffold
err2015-06-18
err20
errOAAI
errOishi, Shinya; Kuroyanagi, Tomoko; Kubo, Tatsuhiko; Montpas, Nicolas; Yoshikawa, Yasushi; Misu, Ryosuke; Kobayashi, Yuka; Ohno, Hiroaki; Heveker, Nikolaus; Furuya, Toshio; Fujii, Nobutaka
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The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin
err2014-07-22
err49
errOAAI
errArmando, Sylvain; Quoyer, Julie; Lukashova, Viktorya; Maiga, Arhamatoulaye; Percherancier, Yann; Heveker, Nikolaus; Pin, Jean-Philippe; Prezeau, Laurent; Bouvier, Michel
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Positive Regulation of Insulin Signaling by Neuraminidase 1
err2013-06-14
err84
errOAAI
errDridi, Larbi; Seyrantepe, Volkan; Fougerat, Anne; Pan, Xuefang; Bonneil, Eric; Thibault, Pierre; Moreau, Allain; Mitchell, Grant A.; Heveker, Nikolaus; Cairo, Christopher W.; Issad, Tarik; Hinek, Alexander; Pshezhetsky, Alexey V.
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Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4
err2012-03-19
err149
errOAAI
errMysinger, Michael M.; Weiss, Dahlia R.; Ziarek, Joshua J.; Gravel, Stephanie; Doak, Allison K.; Karpiak, Joel; Heveker, Nikolaus; Shoichet, Brian K.; Volkman, Brian F.
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Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways
err2011-10-11
err199
errOAAI
errDrury, Luke J.; Ziarek, Joshua J.; Gravel, Stephanie; Veldkamp, Christopher T.; Takekoshi, Tomonori; Hwang, Samuel T.; Heveker, Nikolaus; Volkman, Brian F.; Dwinell, Michael B.
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Direct assessment of CXCR4 mutant conformations reveals complex link between receptor structure and Gαi activation (vol 282, pg 5111, 2007)
err2011-08-01
err0
errOAAI
errBerchiche, Yamina A.; Chow, Ken Y.; Lagane, Bernard; Leduc, Martin; Percherancier, Yann; Fujii, Nobutaka; Tamamura, Hirokazu; Bachelerie, Francoise; Heveker, Nikolaus
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Agonists for the Chemokine Receptor CXCR4
err2011-06-15
err38
errOAAI
errLefrancois, Marilou; Lefebvre, Marie-Reine; Saint-Onge, Genevieve; Boulais, Philip E.; Lamothe, Simon; Leduc, Richard; Lavigne, Pierre; Heveker, Nikolaus; Escher, Emanuel
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Different Effects of the Different Natural CC Chemokine Receptor 2b Ligands on β-Arrestin Recruitment, Gαi Signaling, and Receptor Internalization
err2011-03-01
err52
PREAI
errBerchiche, Yamina A.; Gravel, Stephanie; Pelletier, Marie-Eve; St-Onge, Genevieve; Heveker, Nikolaus
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The Peptidomimetic CXCR4 Antagonist TC14012 Recruits β-Arrestin to CXCR7 ROLES OF RECEPTOR DOMAINS
err2010-12-01
err93
errOAAI
errGravel, Stephanie; Malouf, Camille; Boulais, Philip E.; Berchiche, Yamina A.; Oishi, Shinya; Fujii, Nobutaka; Leduc, Richard; Sinnett, Daniel; Heveker, Nikolaus
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The activity of the HIV-1 IRES is stimulated by oxidative stress and controlled by a negative regulatory element
err2010-10-08
err65
errOAAI
errGendron, Karine; Ferbeyre, Gerardo; Heveker, Nikolaus; Brakier-Gingras, Lea
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Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site
err2009-12-01
err24
PREAI
errBoulais, Philip E.; Dulude, Dominic; Cabana, Jerome; Heveker, Nikolaus; Escher, Emanuel; Lavigne, Pierre; Leduc, Richard
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