Not logged in PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma Giuliani, Virginia; Miller, Meredith A.; Liu, Chiu-Yi; Hartono, Stella R.; Class, Caleb A.; Bristow, Christopher A.; Suzuki, Erika; Sanz, Lionel A.; Gao, Guang; Gay, Jason P.; Feng, Ningping; Rose, Johnathon L.; Tomihara, Hideo; Daniele, Joseph R.; Peoples, Michael D.; Bardenhagen, Jennifer P.; Geck Do, Mary K.; Chang, Qing E.; Vangamudi, Bhavatarini; Vellano, Christopher; Ying, Haoqiang; Deem, Angela K.; Do, Kim-Anh; Genovese, Giannicola; Marszalek, Joseph R.; Kovacs, Jeffrey J.; Kim, Michael; Fleming, Jason B.; Guccione, Ernesto; Viale, Andrea; Maitra, Anirban; Emilia Di Francesco, M.; Yap, Timothy A.; Jones, Philip; Draetta, Giulio; Carugo, Alessandro; Chedin, Frederic; Heffernan, Timothy P. Share Save
Design of BET Inhibitor Bottlebrush Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities Vohidov, Farrukh; Andersen, Jannik N.; Economides, Kyriakos D.; Shipitsin, Michail, V; Burenkova, Olga; Ackley, James C.; Vangamudi, Bhavatarini; Nguyen, Hung V-T; Gallagher, Nolan M.; Shieh, Peyton; Golder, Matthew R.; Liu, Jenny; Dahlberg, William K.; Ehrlich, Deborah J. C.; Kim, Julie; Kristufek, Samantha L.; Huh, Sung Jin; Neenan, Allison M.; Baddour, Joelle; Paramasivan, Sattanathan; de Stanchina, Elisa; Kc, Gaurab; Turnquist, David J.; Saucier-Sawyer, Jennifer K.; Kopesky, Paul W.; Brady, Samantha W.; Jessel, Michael J.; Reiter, Lawrence A.; Chickering, Donald E.; Johnson, Jeremiah A.; Blume-Jensen, Peter Share Save
Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma Giuliani, Virginia; Carugo, Alessandro; Miller, Meredith; Sanz, Lionel; Liu, Chiu-Yi; Bristow, Christopher A.; Suzuki, Erika; Class, Caleb A.; Hartono, Stella R.; Gao, Guang; Feng, Ningping; Gay, Jason P.; Vangamudi, Bhavatarini; Marszalek, Joseph R.; Kovacs, Jeffrey; Di Francesco, Maria Emilia; Chedin, Frederic; Jones, Philip; Draetta, Giulio; Heffernan, Timothy Share Save
Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs (vol 2, pg 1, 2018) Golder, Matthew R.; Liu, Jenny; Andersen, Jannik N.; Shipitsin, Michail V.; Vohidov, Farrukh; Nguyen, Hung V. -T.; Ehrlich, Deborah C.; Huh, Sung Jin; Vangamudi, Bhavatarini; Economides, Kyriakos D.; Neenan, Allison M.; Ackley, James C.; Baddour, Joelle; Paramasivan, Sattanathan; Brady, Samantha W.; Held, Eric J.; Reiter, Lawrence A.; Saucier-Sawyer, Jennifer K.; Kopesky, Paul W.; Chickering, Donald E.; Blume-Jensen, Peter; Johnson, Jeremiah A. Share Save
Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs Golder, Matthew R.; Liu, Jenny; Andersen, Jannik N.; Shipitsin, Michail V.; Vohidov, Farrukh; Nguyen, Hung V. -T.; Ehrlich, Deborah C.; Huh, Sung Jin; Vangamudi, Bhavatarini; Economides, Kyriakos D.; Neenan, Allison M.; Ackley, James C.; Baddour, Joelle; Paramasivan, Sattanathan; Brady, Samantha W.; Held, Eric J.; Reiter, Lawrence A.; Saucier-Sawyer, Jennifer K.; Kopesky, Paul W.; Chickering, Donald E.; Blume-Jensen, Peter; Johnson, Jeremiah A. Share Save
Development of macromolecular prodrugs of BET-bromodomain inhibitors with superior anti-tumor efficacy that are T-cell sparing and devoid of systemic toxicity Vohidov, Farrukh; Andersen, Jannik N.; Economides, Kyriakos D.; Shipitsin, Michail V.; Burenkova, Olga; Gallagher, Nolan M.; Sheih, Peyton; Golder, Matthew; Liu, Jenny; Dahlberg, William K.; Nguyen, Hung V.; Ehrlich, Deborah J.; Kim, Julie; Huh, Sung Jin; Vangamudi, Bhavatarini; Neenan, Allison M.; Ackley, James C.; Baddour, Joelle; Paramasivan, Sattanathan; Gaurab, K. C.; Turnquist, David J.; Saucier-Sawyer, Jenny K.; Kopesky, Paul W.; Brady, Samantha W.; Jessel, Michael J.; Reiter, Lawrence A.; Chickering, Donald E.; Johnson, Jeremiah A.; Blume-Jensen, Peter Share Save
Identification of protein arginine methyltransferase 1 as novel epigenetic vulnerability in KRAS/p53 mutant PDAC primary patient models Giuliani, Virginia; Vangamudi, Bhavatarini; Suzuki, Erika; Miller, Meredith; Liu, Chiu-Yi; Carugo, Alessandro; Bristow, Christopher; Gao, Guang; Han, Jing; Sun, Yuting; Feng, Ningping; Chang, Edward; Marszalek, Joseph; Kovacs, Jeffrey; Di Francesco, Maria Emilia; Toniatti, Carlo; Heffernan, Timothy; Jones, Philip; Draetta, Giulio Share Save
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication ProteinA Patrone, James D.; Pelz, Nicholas F.; Bates, Brittney S.; Souza-Fagundes, Elaine M.; Vangamudi, Bhavatarini; Camper, Demarco V.; Kuznetsov, Alexey G.; Browning, Carrie F.; Feldkamp, Michael D.; Frank, Andreas O.; Gilston, Benjamin A.; Olejniczak, Edward T.; Rossanese, Olivia W.; Waterson, Alex G.; Chazin, Walter J.; Fesik, Stephen W. Share Save
Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery Zhan, Yanai; Kost-Alimova, Maria; Shi, Xi; Leo, Elisabetta; Bardenhagen, Jennifer P.; Shepard, Hannah E.; Appikonda, Srikanth; Vangamudi, Bhavatarini; Zhao, Shuping; Tieu, Trang N.; Jiang, Shiming; Heffernan, Timothy P.; Marszalek, Joseph R.; Toniatti, Carlo; Draetta, Giulio; Tyler, Jessica; Barton, Michelle; Jones, Philip; Palmer, Wylie S.; Do, Mary K. Geck; Andersen, Jannik N. Share Save
The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNFMutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies Vangamudi, Bhavatarini; Paul, Thomas A.; Shah, Parantu K.; Kost-Alimova, Maria; Nottebaum, Lisa; Shi, Xi; Zhan, Yanai; Leo, Elisabetta; Mahadeshwar, Harshad S.; Protopopov, Alexei; Futreal, Andrew; Tieu, Trang N.; Peoples, Mike; Heffernan, Timothy P.; Marszalek, Joseph R.; Toniatti, Carlo; Petrocchi, Alessia; Verhelle, Dominique; Owen, Dafydd R.; Draetta, Giulio; Jones, Philip; Palmer, Wylie S.; Sharma, Shikhar; Andersen, Jannik N. Share Save
The SMARCA2/4 catalytic activity, but not the bromodomain, is a drug target in SWI/SNF mutant cancers Vangamudi, Bhavatarini; Paui, Thomas; Shah, Parantu K.; Alimova, Maria K.; Nottebaum, Lisa; Shi, Xi; Zhan, Yanai; Leo, Elisabetta; Mahadeshwar, Harshad S.; Protopopov, Alexei; Futreal, Andrew; Tieu, Trang N.; Peoples, Mike; Petrocchi, Alessia; Marszalek, Joseph R.; Toniatti, Carlo; Heffernan, Timothy P.; Verhelle, Dominique; Draetta, Giulio; Owen, Dafydd; Jones, Philip; Palmer, Wylie; Sharma, Shikhar; Andersen, Jannik N. Share Save
Discovery of probes to evaluate the disruption of the protein-protein interactions mediated by RPA70N Waterson, Alex G.; Kennedy, Phillip; Patrone, James D.; Pelz, Nicholas F.; Frank, Andreas O.; Vangamudi, Bhavatarini; Camper, DeMarco V.; Souza-Fagundes, Elaine M.; Feldkamp, Michael D.; Olejniczak, Edward T.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W. Share Save
Diphenylpyrazoles as Replication Protein A Inhibitors Waterson, Alex G.; Kennedy, J. Phillip; Patrone, James D.; Pelz, Nicholas F.; Feldkamp, Michael D.; Frank, Andreas O.; Vangamudi, Bhavatarini; Souza-Fagundes, Elaine M.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W. Share Save
Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A Frank, Andreas O.; Vangamudi, Bhavatarini; Feldkamp, Michael D.; Souza-Fagundes, Elaine M.; Luzwick, Jessica W.; Cortez, David; Olejniczak, Edward T.; Waterson, Alex G.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W. Share Save
Discovery of a Potent Inhibitor of Replication Protein A Protein- Protein Interactions Using a Fragment-Linking Approach Frank, Andreas O.; Feldkamp, Michael D.; Kennedy, J. Philip; Waterson, Alex G.; Pelz, Nicholas F.; Patrone, James D.; Vangamudi, Bhavatarini; Camper, DeMarco V.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W. Share Save
Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A Patrone, James D.; Kennedy, J. Phillip; Frank, Andreas O.; Feldkamp, Michael D.; Vangamudi, Bhavatarini; Pelz, Nicholas F.; Rossanese, Olivia W.; Waterson, Alex G.; Chazin, Walter J.; Fesik, Stephen W. Share Save
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