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Séverine Bégard

University of Lille

29H-index
105Paper Count
3.7KCitation Count
Published Papers 34
Publication Date
Amplification of seeding-competent tau aggregates by PMCA in human and experimental tauopathies
err2026-08-14
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errOAAI
errFlorian Almela; Maxime Belondrade; Raphaelle Caillierez; Sarah Leclercq; Thomas Bouillet; Séverine Bégard; Marie Oosterlynck; Sabiha Eddarkaoui; Susana Boluda; Luc Buée; Simon Nicot; Morvane Colin; Daisy Bougard
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Protein fingerprints of brain-derived extracellular vesicles predict types of tau pathology
err2025-10-15
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errJeanne Espourteille; Aatmika Barve; Valentin Zufferey; Elodie Leroux; Romain Perbet; Séverine Bégard; Raphaëlle Caillierez; Claude-Alain Maurage; Nicolas Toni; Luc Buée; Morvane Colin; Kevin Richetin
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Anti-tau VHH therapy against PHF6: a safe approach to slowing the phenotype of tau pathology
err2025-10-08
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errOAAI
errRaphaelle Caillierez; Clémence Leboullenger; Sarah Leclercq; Mélanie Besegher; Séverine Bégard; Florent Auger; Claude-Alain Maurage; Bertrand Accart; Justine Mortelecque; Elian Dupré; Clément Danis; Isabelle Landrieu; Luc Buée; Morvane Colin
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Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice
errBRAIN
IF11.7
err2024-07-05
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errOAAI
errGomez-Murcia, Victoria; Launay, Agathe; Carvalho, Kevin; Burgard, Anaelle; Meriaux, Celine; Caillierez, Raphaelle; Eddarkaoui, Sabiha; Kilinc, Devrim; Siedlecki-Wullich, Dolores; Besegher, Melanie; Begard, Severine; Thiroux, Bryan; Jung, Matthieu; Nebie, Ouada; Wisztorski, Maxence; Deglon, Nicole; Montmasson, Claire; Bemelmans, Alexis-Pierre; Hamdane, Malika; Lebouvier, Thibaud; Vieau, Didier; Fournier, Isabelle; Buee, Luc; Levi, Sabine; Lopes, Luisa, V; Boutillier, Anne-Laurence; Faivre, Emilie; Blum, David
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A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein
err2024-04-01
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errOAAI
errMortelecque, Justine; Zejneli, Orgeta; Begard, Severine; Simoes, Margarida C.; Cantrelle, Francois-Xavier; ElHajjar, Lea; Hanoulle, Xavier; Nguyen, Marine; Rain, Jean-Christophe; Landrieu, Isabelle; Gomes, Claudio M.; Buee, Luc; Danis, Clement; Colin, Morvane; Dupre, Elian
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Integration of Microfluidic Devices with Microelectrode Arrays to Functionally Assay Amyloid-β-Induced Synaptotoxicity
err2024-02-22
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PREAI
errLefebvre, Camille; Vreulx, Anais-Camille; Dumortier, Corentin; Begard, Severine; Gelle, Carla; Siedlecki-Wullich, Dolores; Colin, Morvane; Kilinc, Devrim; Halliez, Sophie
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Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: Possible implication for Alzheimer's disease
err2023-04-01
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errOAAI
errDenechaud, Marine; Geurs, Sarah; Comptdaer, Thomas; Begard, Severine; Nunez, Alejandro Garcia-; Pechereau, Louis-Adrien; Bouillet, Thomas; Vermeiren, Yannick; Deyn, Peter P. De; Perbet, Romain; Deramecourt, Vincent; Maurage, Claude -Alain; Vanderhaegen, Michiel; Vanuytven, Sebastiaan; Lefebvre, Bruno; Bogaert, Elke; Deglon, Nicole; Voet, Thierry; Colin, Morvane; Buee, Luc; Dermaut, Bart; Gala, Marie-Christine
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Tau Transfer via Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System
errCELLS
IF5.2
err2023-03-23
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errOAAI
errPerbet, Romain; Zufferey, Valentin; Leroux, Elodie; Parietti, Enea; Espourteille, Jeanne; Culebras, Lucas; Perriot, Sylvain; Du Pasquier, Renaud; Begard, Severine; Deramecourt, Vincent; Deglon, Nicole; Toni, Nicolas; Buee, Luc; Colin, Morvane; Richetin, Kevin
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Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
err2022-04-01
err29
errOAAI
errDanis, Clement; Dupre, Elian; Zejneli, Orgeta; Caillierez, Raphaelle; Arrial, Alexis; Begard, Severine; Mortelecque, Justine; Eddarkaoui, Sabiha; Loyens, Anne; Cantrelle, Francois-Xavier; Hanoulle, Xavier; Rain, Jean-Christophe; Colin, Morvane; Buee, Luc; Landrieu, Isabelle
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Reversal of RNA toxicity in myotonic dystrophy via a decoy RNA-binding protein with high affinity for expanded CUG repeats
err2022-02-10
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errOAAI
errArandel, Ludovic; Matloka, Magdalena; Klein, Arnaud F.; Rau, Frederique; Sureau, Alain; Ney, Michel; Cordier, Aurelien; Kondili, Maria; Polay-Espinoza, Micaela; Naouar, Naira; Ferry, Arnaud; Lemaitre, Megane; Begard, Severine; Colin, Morvane; Lamarre, Chloe; Tran, Helene; Buee, Luc; Marie, Joelle; Sergeant, Nicolas; Furling, Denis
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Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies
err2022-02-01
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errLeroux, Elodie; Perbet, Romain; Caillierez, Raphaelle; Richetin, Kevin; Lieger, Sarah; Espourteille, Jeanne; Bouillet, Thomas; Begard, Severine; Danis, Clement; Loyens, Anne; Toni, Nicolas; Deglon, Nicole; Deramecourt, Vincent; Schraen-Maschke, Susanna; Buee, Luc; Colin, Morvane
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Low impedance and highly transparent microelectrode arrays (MEA) for in vitro neuron electrical activity probing
err2021-01-01
err30
errOAAI
errSusloparova, Anna; Halliez, Sophie; Begard, Severine; Colin, Morvane; Buee, Luc; Pecqueur, Sebastien; Alibart, Fabien; Thomy, Vincent; Arscott, Steve; Pallecchi, Emiliano; Coffinier, Yannick
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The effect of thermal treatment on the neuronal cell biocompatibility of SU-8
err2020-09-01
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errBaetens, Tiffany; Begard, Severine; Pallecchi, Emiliano; Thomy, Vincent; Arscott, Steve; Halliez, Sophie
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Isolation of microglia-derived extracellular vesicles: towards miRNA signatures and neuroprotection
err2019-12-04
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errLemaire, Quentin; Raffo-Romero, Antonella; Arab, Tanina; Van Camp, Christelle; Drago, Francesco; Forte, Stefano; Gimeno, Jean-Pascal; Begard, Severine; Colin, Morvane; Vizioli, Jacopo; Sautiere, Pierre-Eric; Salzet, Michel; Lefebvre, Christophe
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Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process
err2019-03-04
err58
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errDomise, Manon; Sauve, Florent; Didier, Sebastien; Caillerez, Raphaelle; Begard, Severine; Carrier, Sebastien; Colin, Morvane; Marinangeli, Claudia; Buee, Luc; Vingtdeux, Valerie
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Different tau species lead to heterogeneous tau pathology propagation and misfolding
err2018-11-29
err77
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errDujardin, Simon; Begard, Severine; Caillierez, Raphaelle; Lachaud, Cedrick; Carrier, Sebastien; Lieger, Sarah; Gonzalez, Jose A.; Deramecourt, Vincent; Deglon, Nicole; Maurage, Claude-Alain; Frosch, Matthew P.; Hyman, Bradley T.; Colin, Morvane; Buee, Luc
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Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies
err2016-11-04
err230
errOAAI
errTardivel, Meryem; Begard, Severine; Bousset, Luc; Dujardin, Simon; Coens, Audrey; Melki, Ronald; Buee, Luc; Colin, Morvane
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Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin
err2016-09-08
err110
errOAAI
errMansuroglu, Zeyni; Benhelli-Mokrani, Houda; Marcato, Vasco; Sultan, Audrey; Violet, Marie; Chauderlier, Alban; Delattre, Lucie; Loyens, Anne; Talahari, Smail; Begard, Severine; Nesslany, Fabrice; Colin, Morvane; Soues, Sylvie; Lefebvre, Bruno; Buee, Luc; Galas, Marie-Christine; Bonnefoy, Eliette
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Melanoma dormancy in a mouse model is linked to GILZ/FOXO3A-dependent quiescence of disseminated stem-like cells
err2016-07-28
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errTouil, Yasmine; Segard, Pascaline; Ostyn, Pauline; Begard, Severine; Aspord, Caroline; El Machhour, Raja; Masselot, Bernadette; Vandomme, Jerome; Flamenco, Pilar; Idziorek, Thierry; Figeac, Martin; Formstecher, Pierre; Quesnel, Bruno; Polakowska, Renata
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THE INS AND OUTS OF TAU PROPAGATION
err2016-03-01
err0
PREAI
errBuee, Luc; Dujardin, Simon; Tardivel, Meryem; Begard, Severine; Caillierez, Raphaelle; Bousset, Luc; Melki, Ronald; Colin, Morvane
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