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Gary J. Spencer

university of toronto

23H-index
59Paper Count
3.4KCitation Count
Published Papers 19
Publication Date
Association Between Delayed Discharge From Acute Care and Rehabilitation Outcomes and Length of Stay: A Retrospective Cohort Study
err2023-01-01
err2
errOAAI
errGorgulu, Berk; Dong, Jing; Hunter, Karen; Bettio, Krista M.; Vukusic, Betty; Ranisau, Jonathan; Spencer, Gary; Tang, Terence; Sarhangian, Vahid
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HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block
err2022-09-28
err3
errOAAI
errMaiques-Diaz, Alba; Nicosia, Luciano; Basma, Naseer J.; Romero-Camarero, Isabel; Camera, Francesco; Spencer, Gary J.; Amaral, Fabio M. R.; Simeoni, Fabrizio; Wingelhofer, Bettina; Williamson, Andrew J. K.; Pierce, Andrew; Whetton, Anthony D.; Somervaille, Tim C. P.
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Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
err2021-09-01
err18
errOAAI
errSimeoni, Fabrizio; Romero-Camarero, Isabel; Camera, Francesco; Amaral, Fabio M. R.; Sinclair, Oliver J.; Papachristou, Evangelia K.; Spencer, Gary J.; Lie-A-Ling, Michael; Lacaud, Georges; Wiseman, Daniel H.; Carroll, Jason S.; Somervaille, Tim C. P.
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Pre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia
errLEUKEMIA
IF13.4
err2019-11-28
err23
errOAAI
errDeb, Gauri; Wingelhofer, Bettina; Amaral, Fabio M. R.; Maiques-Diaz, Alba; Chadwick, John A.; Spencer, Gary J.; Williams, Emma L.; Leong, Hui-Sun; Maes, Tamara; Somervaille, Tim C. P.
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Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia
err2019-07-01
err369
errOAAI
errParis, Jasmin; Morgan, Marcos; Campos, Joana; Spencer, Gary J.; Shmakova, Alena; Ivanova, Ivayla; Mapperley, Christopher; Lawson, Hannah; Wotherspoon, David A.; Sepulveda, Catarina; Vukovic, Milica; Allen, Lewis; Sarapuu, Annika; Tavosanis, Andrea; Guitart, Amelie V.; Villacreces, Arnaud; Much, Christian; Choe, Junho; Azar, Ali; van de Lagemaat, Louie N.; Vernimmen, Douglas; Nehme, Ali; Mazurier, Frederic; Somervaille, Tim C. P.; Gregory, Richard I.; O'Carroll, Donal; Kranc, Kamil R.
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Novel small molecule inhibitors of p300/CBP down-regulate androgen receptor (AR) and c-Myc for the treatment of prostate cancer and beyond
err2018-07-01
err3
PREAI
errPegg, Neil; Worthington, Jenny; Young, Barbara; Prosser, Amy; Gaughan, Luke; Spencer, Gary; Somervaille, Tim; Burns, Julie; Knowles, Margaret; Brooks, Nigel
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Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia
err2018-03-01
err153
errOAAI
errMaiques-Diaz, Alba; Spencer, Gary J.; Lynch, James T.; Ciceri, Filippo; Williams, Emma L.; Amaral, Fabio M. R.; Wiseman, Daniel H.; Harris, William J.; Li, Yaoyong; Sahoo, Sudhakar; Hitchin, James R.; Mould, Daniel P.; Fairweather, Emma E.; Waszkowycz, Bohdan; Jordan, Allan M.; Smith, Duncan L.; Somervaille, Tim C. P.
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Derepression of the Iroquois Homeodomain Transcription Factor Gene IRX3 Confers Differentiation Block in Acute Leukemia
err2018-01-01
err20
errOAAI
errSomerville, Tim D. D.; Simeoni, Fabrizio; Chadwick, John A.; Williams, Emma L.; Spencer, Gary J.; Boros, Katalin; Wirth, Christopher; Tholouli, Eleni; Byers, Richard J.; Somervaille, Tim C. P.
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Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1
err2017-09-21
err38
errOAAI
errMould, Daniel P.; Alli, Cristina; Bremberg, Ulf; Cartic, Sharon; Jordan, Allan M.; Geitmann, Matthis; Maiques-Diaz, Alba; McGonagle, Alison E.; Somervaille, Tim C. P.; Spencer, Gary J.; Turlais, Fabrice; Ogilvie, Donald
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Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells
err2016-12-05
err49
errOAAI
errJones, Stuart; Ahmet, Jonathan; Ayton, Kelly; Ball, Matthew; Cockerill, Mark; Fairweather, Emma; Hamilton, Nicola; Harper, Paul; Hitchin, James; Jordan, Allan; Levy, Colin; Lopez, Ruth; McKenzie, Eddie; Packer, Martin; Plant, Darren; Simpson, Iain; Simpson, Peter; Sinclair, Ian; Somervaille, Tim C. P.; Small, Helen; Spencer, Gary J.; Thomson, Graeme; Tonge, Michael; Waddell, Ian; Walsh, Jarrod; Waszkowycz, Bohdan; Wigglesworth, Mark; Wiseman, Daniel H.; Ogilvie, Donald
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A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival
err2014-03-31
err63
errOAAI
errJude, J. G.; Spencer, G. J.; Huang, X.; Somerville, T. D. D.; Jones, D. R.; Divecha, N.; Somervaille, T. C. P.
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Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells
errLEUKEMIA
IF13.4
err2013-10-29
err33
errOAAI
errHuang, X.; Spencer, G. J.; Lynch, J. T.; Ciceri, F.; Somerville, T. D. D.; Somervaille, T. C. P.
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TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells
err2013-04-04
err17
errOAAI
errLynch, J. T.; Somerville, T. D. D.; Spencer, G. J.; Huang, X.; Somervaille, T. C. P.
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Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells
err2009-02-01
err339
errOAAI
errSomervaille, Tim C. P.; Matheny, Christina J.; Spencer, Gary J.; Iwasaki, Masayuki; Rinn, John L.; Witten, Daniela M.; Chang, Howard Y.; Shurtleff, Sheila A.; Downing, James R.; Cleary, Michael L.
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Expression profiling and functional analysis of Wnt signaling mechanisms in mesenchymal stem cells
err2008-12-23
err359
errOAAI
errEtheridge, SL; Spencer, GJ; Heath, DJ; Genever, PG
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Current perspectives on NMDA-type glutamate signalling in bone
err2007-01-01
err36
PREAI
errSpencer, Gary J.; McGrath, Catherine J.; Genever, Paul G.
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Emerging neuroskeletal signalling pathways: a review
err2004-01-23
err53
errOAAI
errSpencer, GJ; Hitchcock, IS; Genever, PG
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