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Al-Amin, Rasel A.; Johansson, Lars; Abdurakhmanov, Eldar; Landegren, Nils; Lof, Liza; Arngarden, Linda; Blokzijl, Andries; Svensson, Richard; Hammond, Maria; Lonn, Peter; Haybaeck, Johannes; Kamali-Moghaddam, Masood; Jensen, Annika Jenmalm; Danielson, U. Helena; Artursson, Per; Lundback, Thomas; Landegren, Ulf .png)
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SavePiperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors (vol 60, pg 4279, 2017)Llona-Minguez, Sabin; Hoglund, Andreas; Ghassemian, Artin; Desroses, Matthieu; Calderon-Montano, Jose Manuel; Moron, Estefania Burgos; Valerie, Nicholas C. K.; Wiita, Elisee; Almlof, Ingrid; Koolmeister, Tobias; Mateus, Andre; Cazares-Korner, Cindy; Sanjiv, Kumar; Homan, Evert; Loseva, Olga; Baranczewski, Pawel; Darabi, Masoud; Mehdizadeh, Amir; Fayezi, Shabnam; Jemth, Ann-Sofie; Berglund, Ulrika Warpman; Sigmundsson, Kristmundur; Lundback, Thomas; Jensen, Annika Jenmalm; Artursson, Per; Scobie, Martin; Helleday, Thomas Share Save Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 InhibitorsLlona-Minguez, Sabin; Hoglund, Andreas; Ghassemian, Artin; Desroses, Matthieu; Calderon-Montano, Jose Manuel; Moron, Estefania Burgos; Valerie, Nicholas C. K.; Wiita, Elisee; Almlof, Ingrid; Koolmeister, Tobias; Mateus, Andre; Cazares-Korner, Cindy; Sanjiv, Kumar; Homan, Evert; Loseva, Olga; Baranczewski, Pawel; Darabi, Masoud; Mehdizadeh, Amir; Fayezi, Shabnam; Jemth, Ann-Sofie; Berglund, Ulrika Warpman; Sigmundsson, Kristmundur; Lundback, Thomas; Jensen, Annika Jenmalm; Artursson, Per; Scobie, Martin; Helleday, Thomas Share Save Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1Llona-Minguez, Sabin; Hoglund, Andreas; Wiita, Elisee; Almlof, Ingrid; Mateus, Andre; Calderon-Montano, Jose Manuel; Cazares-Korner, Cindy; Homan, Evert; Loseva, Olga; Baranczewski, Pawel; Jemth, Ann-Sofie; Haggblad, Maria; Martens, Ulf; Lundgren, Bo; Artursson, Per; Lundback, Thomas; Jensen, Annika Jenmalm; Berglund, Ulrika Warpman; Scobie, Martin; Helledayt, Thomas Share Save Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1Llona-Minguez, Sabin; Hoglund, Andreas; Jacques, Sylvain A.; Johanson, Lars; Calderon-Montano, Jose Manuel; Claesson, Magnus; Loseva, Olga; Valerie, Nicholas C. K.; Lundback, Thomas; Piedrafita, Javier; Maga, Giovanni; Crespan, Emmanuele; Meijer, Laurent; Moron, Estefania Burgos; Baranczewski, Pawel; Hagbjork, Ann-Louise; Svensson, Richard; Wiita, Elisee; Almlof, Ingrid; Visnes, Torkild; Jeppsson, Fredrik; Sigmundsson, Kristmundur; Jensen, Annika Jenmalm; Artursson, Per; Jemth, Ann-Sofie; Stenmark, Pal; Berglund, Ulrika Warpman; Scobie, Martin; Helleday, Thomas Share Save Share Save Share Save Share Save The novel tyrosine kinase inhibitor AKN-028 has significant antileukemic activity in cell lines and primary cultures of acute myeloid leukemiaEriksson, A.; Hermanson, M.; Wickstrom, M.; Lindhagen, E.; Ekholm, C.; Jensen, A. Jenmalm; Lothgren, A.; Lehmann, F.; Larsson, R.; Parrow, V.; Hoglund, M. Share Save Share Save Identification of AKN-032, a novel 2-aminopyrazine tyrosine kinase inhibitor, with significant preclinical activity in acute myeloid leukemiaEriksson, Anna; Hoglund, Martin; Lindhagen, Elin; Aleskog, Anna; Hassan, Sadia Bashir; Ekholm, Carina; Fholenhag, Karin; Jensen, Annika Jenmalm; Lothgren, Agneta; Scobie, Martin; Larsson, Rolf; Parrow, Vendela Share Save 
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