Not logged inNeuropilin Antagonists (NRPas) Block the Phosphorylation of the Cancer Therapeutic Key Factor p38α Kinase Triggering Cell Death
Borriello, Lucia; Jarray, Rafika; Rignault-Bricard, Rachel; Montes, Matthieu; Lopez, Nicolas; Maciel, Thiago Trovati; Hermine, Olivier; Raynaud, Francoise; Demange, Luc; Lepelletier, Yves .png)
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SaveShare Save Share Save A Potent Solution for Tumor Growth and Angiogenesis Suppression via an ELR+CXCL-CXCR1/2 Pathway InhibitorGrytsai, Oleksandr; Dufies, Maeva; Le Du, Julie; Rastoin, Olivia; Goncalves, Leticia Christina Pires; Mateo, Lou; Lacas-Gervais, Sandra; Cao, Yihai; Demange, Luc; Pages, Gilles; Benhida, Rachid; Ronco, Cyril Share Save Share Save Share Save Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinomaDumond, Aurore; Brachet, Etienne; Durivault, Jerome; Vial, Valerie; Puszko, Anna K.; Lepelletier, Yves; Montemagno, Christopher; Pagnuzzi-Boncompagni, Marina; Hermine, Olivier; Garbay, Christiane; Lagarde, Nathalie; Montes, Matthieu; Demange, Luc; Grepin, Renaud; Pages, Gilles Share Save New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatmentsDufies, Maeva; Grytsai, Oleksandr; Ronco, Cyril; Camara, Oumar; Ambrosetti, Damien; Hagege, Anais; Parola, Julien; Mateo, Lou; Ayrault, Marion; Giuliano, Sandy; Grepin, Renaud; Lagarde, Nathalie; Montes, Matthieu; Auberger, Patrick; Demange, Luc; Benhida, Rachid; Pages, Gilles Share Save NRPa-308, a new neuropilin-1 antagonist, exerts in vitro anti-angiogenic and anti-proliferative effects and in vivo anti-cancer effects in a mouse xenograft modelLiu, Wang-Qing; Lepelletier, Yves; Montes, Matthieu; Borriello, Lucia; Jarray, Rafika; Grepin, Renaud; Leforban, Bertrand; Loukaci, Ali; Benhida, Rachid; Hermine, Olivier; Dufour, Sylvie; Pages, Gilles; Garbay, Christiane; Raynaud, Francoise; Hadj-Slimane, Reda; Demange, Luc Share Save Share Save Share Save Share Save Disruption of phactr-1 pathway triggers pro-inflammatory and pro-atherogenic factors: New insights in atherosclerosis developmentJarray, Rafika; Pavoni, Serena; Borriello, Lucia; Allain, Barbara; Lopez, Nicolas; Bianco, Sara; Liu, Wang-Qing; Biard, Denis; Demange, Luc; Hermine, Olivier; Garbay, Christiane; Raynaud, Francoise; Lepelletier, Yves Share Save Share Save Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer modelBorriello, Lucia; Montes, Matthieu; Lepelletier, Yves; Leforban, Bertrand; Liu, Wang-Qing; Demange, Luc; Delhomme, Brigitte; Pavoni, Serena; Jarray, Rafika; Boucher, Jean Luc; Dufour, Sylvie; Hermine, Olivier; Garbay, Christiane; Hadj-Slimane, Reda; Raynaud, Francoise Share Save The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonistMoulin, Aline; Brunel, Luc; Boeglin, Damien; Demange, Luc; Ryan, Johanne; M'Kadmi, Celine; Denoyelle, Severine; Martinez, Jean; Fehrentz, Jean-Alain Share Save Share Save Share Save Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1Oumata, Nassima; Bettayeb, Karima; Ferandin, Yoan; Demange, Luc; Lopez-Giral, Angela; Goddard, Marie-Lorene; Myrianthopoulos, Vassilios; Mikros, Emmanuel; Flajolet, Marc; Greengard, Paul; Meijer, Laurent; Galons, Herve Share Save New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluationsMoulin, Aline; Demange, Luc; Ryan, Joanne; Mousseaux, Delphine; Sanchez, Pierre; Berge, Gilbert; Gagne, Didier; Perrissoud, Daniel; Locatelli, Vittorio; Torsello, Antonio; Galleyrand, Jean-Claude; Fehrentz, Jean-Alain; Martinez, Jean Share Save 
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