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Zhou, Zhicheng; Staropoli, Isabelle; Brelot, Anne; Suzanne, Peggy; Lesnard, Aurelien; Fontaine, Fanny; Perato, Serge; Rault, Sylvain; Helynck, Olivier; Arenzana-Seisdedos, Fernando; Santos, Jana Sopkova-de Oliveira; Lagane, Bernard; Munier-Lehmann, Helene; Colin, Philippe .png)
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SaveA New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant ParasitesBosson-Vanga, Henriette; Primas, Nicolas; Franetich, Jean-Francois; Lavazec, Catherine; Gomez, Lina; Ashraf, Kutub; Tefit, Maurel; Soulard, Valerie; Dereuddre-Bosquet, Nathalie; Le Grand, Roger; Donnette, Melanie; Mustiere, Romain; Amanzougaghene, Nadia; Tajeri, Shahin; Suzanne, Peggy; Malzert-Freon, Aurelie; Rault, Sylvain; Vanelle, Patrice; Hutter, Sebastien; Cohen, Anita; Snounou, Georges; Roques, Pierre; Azas, Nadine; Lagardere, Prisca; Lisowski, Vincent; Masurier, Nicolas; Nguyen, Michel; Paloque, Lucie; Benoit-Vical, Francoise; Verhaeghe, Pierre; Mazier, Dominique Share Save Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerizationCeramella, Jessica; Caruso, Anna; Occhiuzzi, Maria Antonietta; Lacopetta, Domenico; Barbarossa, Alexia; Rizzuti, Bruno; Dallemagne, Patrick; Rault, Sylvain; El-Kashef, Hussein; Saturnino, Carmela; Grande, Fedora; Sinicropi, Maria Stefania Share Save Structure-guided design of pyridoclax derivatives based on Noxa/Mcl-1 interaction modeHedir, Siham; De Giorgi, Marcella; Fogha, Jade; De Pascale, Martina; Weiswald, Louis-Bastien; Brotin, Emilie; Marekha, Bogdan; Denoyelle, Christophe; Denis, Camille; Suzanne, Peggy; Gautier, Fabien; Juin, Philippe; Ligat, Laetitia; Lopez, Frederic; Carlier, Ludovic; Legay, Remi; Bureau, Ronan; Rault, Sylvain; Poulain, Laurent; Santos, Jana Sopkova-de Oliveira; Voisin-Chiret, Anne Sophie Share Save Pyridoclax and its derivatives from oligopyridine family directly inhibit Mcl-1 and exert potent antitumor effects on ovarian cancer in vitro and in vivoHedir, Siham; Weiswald, Louis-Bastien; De Giorgi, Marcella; Fogha, Jade; De Pascale, Martina; Brotin, Emilie; Marekha, Bogdan; Suzanne, Peggy; Gautier, Fabien; Juin, Philippe; Ligat, Laetitia; Lopez, Frederic; Legay, Remi; Bureau, Ronan; Rault, Sylvain; Santos, Jana Sopkova-de Oliveira; Voisin-Chiret, Anne-Sophie; Poulain, Laurent Share Save Share Save Share Save Multifaceted properties of 1,4-dimethylcarbazoles: Focus on trimethoxybenzamide and trimethoxyphenylurea derivatives as novel human topoisomerase II inhibitorsIacopetta, Domenico; Rosano, Camillo; Puoci, Francesco; Parisi, Ortensia Ilaria; Saturnino, Carmela; Caruso, Anna; Longo, Pasquale; Ceramella, Jessica; Malzert-Freon, Aurelie; Dallemagne, Patrick; Rault, Sylvain; Sinicropi, Maria Stefania Share Save The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation ComponentsRaj, Shriya; Krishnan, Karthik; Askew, David S.; Helynck, Olivier; Suzanne, Peggy; Lesnard, Aurelien; Rault, Sylvain; Zeidler, Ute; d'Enfert, Christophe; Latge, Jean-Paul; Munier-Lehmann, Helene; Saveanu, Cosmin Share Save 3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1 (2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progressionRizza, Pietro; Pellegrino, Michele; Caruso, Anna; Iacopetta, Domenico; Sinicropi, Maria Stefania; Rault, Sylvain; Lancelot, Jean Charles; El-Kashef, Hussein; Lesnard, Aurelien; Rochais, Christophe; Dallemagne, Patrick; Saturnino, Carmela; Giordano, Francesca; Catalano, Stefania; Ando, Sebastiano Share Save Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of PlasmodiumCohen, Anita; Suzanne, Peggy; Lancelot, Jean-Charles; Verhaeghe, Pierre; Lesnard, Aurelien; Basmaciyan, Louise; Hutter, Sebastien; Laget, Michele; Dumetre, Aurelien; Paloque, Lucie; Deharo, Eric; Crozet, Maxime D.; Rathelot, Pascal; Dallemagne, Patrick; Lorthiois, Audrey; Sibley, Carol Hopkins; Vanelle, Patrice; Valentin, Alexis; Mazier, Dominique; Rault, Sylvain; Azas, Nadine Share Save Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one seriesKieffer, Charline; Cohen, Anita; Verhaeghe, Pierre; Paloque, Lucie; Hutter, Sebastien; Castera-Ducros, Caroline; Laget, Michele; Rault, Sylvain; Valentin, Alexis; Rathelot, Pascal; Azas, Nadine; Vanelle, Patrice Share Save Share Save Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one seriesKieffer, Charline; Cohen, Anita; Verhaeghe, Pierre; Hutter, Sebastien; Castera-Ducros, Caroline; Laget, Michele; Remusat, Vincent; M'Rabet, Manel Kraiem; Rault, Sylvain; Rathelot, Pascal; Azas, Nadine; Vanelle, Patrice Share Save First Evidence That Oligopyridines, α-Helix Foldamers, Inhibit Mcl-1 and Sensitize Ovarian Carcinoma Cells to Bcl-xL-Targeting StrategiesGloaguen, Celine; Voisin-Chiret, Anne Sophie; Santos, Jana Sopkova-de Oliveira; Fogha, Jade; Gautier, Fabien; De Giorgi, Marcella; Burzicki, Gregory; Perato, Serge; Petigny-Lechartier, Cecile; Simonin-Le Jeune, Karin; Brotin, Emilie; Goux, Didier; N'Diaye, Monique; Lambert, Bernard; Louis, Marie-Helene; Ligat, Laetitia; Lopez, Frederic; Juin, Philippe; Bureau, Ronan; Rault, Sylvain; Poulain, Laurent Share Save Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agentsPrimas, Nicolas; Suzanne, Peggy; Verhaeghe, Pierre; Hutter, Sebastien; Kieffer, Charline; Laget, Michele; Cohen, Anita; Broggi, Julie; Lancelot, Jean-Charles; Lesnard, Aurelien; Dallemagne, Patrick; Rathelot, Pascal; Rault, Sylvain; Vanelle, Patrice; Azas, Nadine Share Save Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and PolypharmacologyLepailleur, Alban; Freret, Thomas; Lemaitre, Stephane; Boulouard, Michel; Dauphin, Francois; Hinschberger, Antoine; Dulin, Fabienne; Lesnard, Aurelien; Bureau, Ronan; Rault, Sylvain Share Save Share Save N-substituted Piperazinopyridylsteroid Derivatives as Abiraterone Analogues Inhibit Growth and Induce Pro-apoptosis in Human Hormone-independent Prostate Cancer Cell LinesBrossard, Dominique; Zhang, Ying; Haider, Shozeb M.; Sgobba, Miriam; Khalid, Mohamed; Legay, Remi; Duterque-Coquillaud, Martine; Galera, Philippe; Rault, Sylvain; Dallemagne, Patrick; Moslemi, Safa; El Kihel, Laila Share Save Share Save 
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