logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
J

John F.X. Diffley

The Francis Crick Institute

76H-index
194Paper Count
2.0WCitation Count
Published Papers 77
Publication Date
logo
Publisher Correction: Targeting cancer-specific mutations with RNA-triggered chromatin shredding
errNature
IF48.5
err2026-08-14
err0
PREAI
errJingkun Zeng; Zhiyuan Cheng; Huadong Chen; Zhaojun Wang; Jared Thompson; Kadin T. Crosby; Hesong Han; Arushi Singhal; Wayne Ngo; Chenglong Xia; Daniel Rosas-Rivera; Zeyuan Zhang; Min Hyung Kang; Ying Mao; Morgan E. Diolaiti; Giselle C. Lee; John F. X. Diffley; Yixuan Song; Longhui Qiu; Nathan M. Krah; Niren Murthy; Ryan N. Jackson; Yang Liu; Alan Ashworth; Jennifer A. Doudna
errShare
errSave
Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding
errNature
IF48.5
err2026-06-08
err0
PREAI
errJingkun Zeng; Zhiyuan Cheng; Huadong Chen; Zhaojun Wang; Jared Thompson; Kadin T. Crosby; Hesong Han; Arushi Singhal; Wayne Ngo; Chenglong Xia; Daniel Rosas-Rivera; Zeyuan Zhang; Min Hyung Kang; Ying Mao; Morgan E. Diolaiti; Giselle C. Lee; John F. X. Diffley; Yixuan Song; Longhui Qiu; Nathan M. Krah; Niren Murthy; Ryan N. Jackson; Yang Liu; Alan Ashworth; Jennifer A. Doudna
errShare
errSave
Replisome passage through the cohesin ring
errCell
IF42.5
err2025-09-16
err0
errOAAI
errSamson Glaser; Maxim I. Molodtsov; John F.X. Diffley; Frank Uhlmann
errShare
errSave
Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication
errMolecular Cell
IF16.6
err2025-09-16
err0
PREAI
errMasashi Minamino; John F.X. Diffley; Frank Uhlmann
errShare
errSave
S-phase checkpoint protects from aberrant replication fork processing and degradation
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-08-12
err1
PREAI
errNunez-Martin, Ivan; Drury, Lucy S.; Martinez-Jimenez, Maria, I; Blanco, Luis; Diffley, John F. X.; Aguilera, Andres; Gomez-Gonzalez, Belen
errShare
errSave
Mechanisms for licensing origins of DNA replication in eukaryotic cells
errNature Structural & Molecular Biology
IF10.1
err2025-06-30
err0
PREAI
errBruce Stillman; John F. X. Diffley; Janet H. Iwasa
errShare
errSave
Cell cycle regulation has shaped replication origins in budding yeast
errNature Structural & Molecular Biology
IF10.1
err2025-06-30
err0
errOAAI
errChew Theng Lim; Thomas C. R. Miller; Kang Wei Tan; Saurabh Talele; Anne Early; Philip East; Humberto Sánchez; Nynke H. Dekker; Alessandro Costa; John F. X. Diffley
errShare
errSave
Unwinding of a eukaryotic origin of replication visualized by cryo-EM (vol 31, 1265, 2024)
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-09-09
err0
errOAAI
errHenrikus, Sarah S.; Gross, Marta H.; Willhoft, Oliver; Puhringer, Thomas; Lewis, Jacob S.; McClure, Allison W.; Greiwe, Julia F.; Palm, Giacomo; Nans, Andrea; Diffley, John F. X.; Costa, Alessandro
errShare
errSave
Unwinding of a eukaryotic origin of replication visualized by cryo-EM
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-05-17
err8
errOAAI
errHenrikus, Sarah S.; Gross, Marta H.; Willhoft, Oliver; Puehringer, Thomas; Lewis, Jacob S.; Mcclure, Allison W.; Greiwe, Julia F.; Palm, Giacomo; Nans, Andrea; Diffley, John F. X.; Costa, Alessandro
errShare
errSave
A chromatinized origin reduces the mobility of ORC and MCM through interactions and spatial constraint
errNATURE COMMUNICATIONS
IF15.7
err2023-10-23
err2
errOAAI
errSanchez, Humberto; Liu, Zhaowei; van Veen, Edo; van Laar, Theo; Diffley, John F. X.; Dekker, Nynke H.
errShare
errSave
Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation
errNATURE COMMUNICATIONS
IF15.7
err2023-04-14
err9
errOAAI
errRamirez Montero, Daniel; Sanchez, Humberto; van Veen, Edo; van Laar, Theo; Solano, Belen; Diffley, John F. X.; Dekker, Nynke H.
errShare
errSave
Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err143
errOAAI
errWang, X; Ira, G; Tercero, JA; Holmes, AM; Diffley, JFX; Haber, JE
errShare
errSave
A DNA replication fork-centric view of the budding yeast DNA damage response
errDNA REPAIR
IF2.7
err2022-11-01
err10
errOAAI
errMcClure, Allison W.; Canal, Berta; Diffley, John F. X.
errShare
errSave
The Initiation of Eukaryotic DNA Replication
errANNUAL REVIEW OF BIOCHEMISTRY
IF20.5
err2022-06-21
err93
errOAAI
errCosta, Alessandro; Diffley, John F. X.
errShare
errSave
Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2021-12-28
err25
errOAAI
errGreiwe, Julia F.; Miller, Thomas C. R.; Locke, Julia; Martino, Fabrizio; Howell, Steven; Schreiber, Anne; Nans, Andrea; Diffley, John F. X.; Costa, Alessandro
errShare
errSave
Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
errELIFE
IF0
err2021-08-13
err0
errOAAI
errMcClure, Allison W.; Diffley, John F. X.
errShare
errSave
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase
errBIOCHEMICAL JOURNAL
IF4.3
err2021-07-02
err37
errOAAI
errBasu, Souradeep; Mak, Tiffany; Ulferts, Rachel; Wu, Mary; Deegan, Tom; Fujisawa, Ryo; Tan, Kang Wei; Lim, Chew Theng; Basier, Clovis; Canal, Berta; Curran, Joseph F.; Drury, Lucy S.; McClure, Allison W.; Roberts, Emma L.; Weissmann, Florian; Zeisner, Theresa U.; Beale, Rupert; Cowling, Victoria H.; Howell, Michael; Labib, Karim; Diffley, John F. X.
errShare
errSave
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease
errBIOCHEMICAL JOURNAL
IF4.3
err2021-07-02
err45
errOAAI
errLim, Chew Theng; Tan, Kang Wei; Wu, Mary; Ulferts, Rachel; Armstrong, Lee A.; Ozono, Eiko; Drury, Lucy S.; Milligan, Jennifer C.; Zeisner, Theresa U.; Zeng, Jingkun; Weissmann, Florian; Canal, Berta; Bineva-Todd, Ganka; Howell, Michael; O'Reilly, Nicola; Beale, Rupert; Kulathu, Yogesh; Labib, Karim; Diffley, John F. X.
errShare
errSave
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease
errBIOCHEMICAL JOURNAL
IF4.3
err2021-07-02
err32
errOAAI
errCanal, Berta; McClure, Allison W.; Curran, Joseph F.; Wu, Mary; Ulferts, Rachel; Weissmann, Florian; Zeng, Jingkun; Bertolin, Agustina P.; Milligan, Jennifer C.; Basu, Souradeep; Drury, Lucy S.; Deegan, Tom D.; Fujisawa, Ryo; Roberts, Emma L.; Basier, Clovis; Labib, Karim; Beale, Rupert; Howell, Michael; Diffley, John F. X.
errShare
errSave
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease
errBIOCHEMICAL JOURNAL
IF4.3
err2021-07-02
err30
errOAAI
errMilligan, Jennifer . C.; Zeisner, Theresa U.; Papageorgiou, George; Joshi, Dhira; Soudy, Christelle; Ulferts, Rachel; Wu, Mary; Lim, Chew Theng; Tan, Kang Wei; Weissmann, Florian; Canal, Berta; Fujisawa, Ryo; Deegan, Tom; Nagaraj, Hema; Bineva-Todd, Ganka; Basier, Clovis; Curran, Joseph F.; Howell, Michael; Beale, Rupert; Labib, Karim; Reilly, Nicola. O.; Diffley, John F. X.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
S
Stephen J. Elledge
H-index: 172 · Papers: 542
J
Jennifer A. Doudna
H-index: 149 · Papers: 672
C
Chris P. Ponting
H-index: 135 · Papers: 518
J
James E. Haber
H-index: 124 · Papers: 539
A
Alan Ashworth
H-index: 121 · Papers: 1.0K
View more