Not logged in Anoikis resistance and metastasis of ovarian cancer can be overcome by CDK8/19 mediator kinase inhibition Monavarian, Mehri; Rajkarnikar, Resha; Page, Emily Faith; Kumari, Asha; Macias, Liz Quintero; Massicano, Felipe; Lee, Nam Y.; Sahoo, Sarthak; Hempel, Nadine; Jolly, Mohit Kumar; Ianov, Lara; Worthey, Elizabeth; Singh, Abhyudai; Roninson, Igor B.; Broude, Eugenia V.; Chen, Mengqian; Mythreye, Karthikeyan Share Save
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CDK8/19 inhibition attenuates G1 arrest induced by BCR-ABL antagonists and accelerates death of chronic myelogenous leukemia cells Khamidullina, Alvina I.; Yastrebova, Margarita A.; Bruter, Alexandra V.; Nuzhina, Julia V.; Vorobyeva, Nadezhda E.; Khrustaleva, Anastasia M.; Varlamova, Ekaterina A.; Tyakht, Alexander V.; Abramenko, Iaroslav E.; Ivanova, Ekaterina S.; Zamkova, Maria A.; Li, Jing; Lim, Chang-Uk; Chen, Mengqian; Broude, Eugenia V.; Roninson, Igor B.; Shtil, Alexander A.; Tatarskiy, Victor V. Share Save
Mediator kinase inhibitors suppress triple- negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors Ding, Xiaokai; Liang, Jiaxin; Sharko, Amanda C.; Hilimire, Thomas A.; Li, Jing; Loskutov, Jurgen; Mack, Zachary T.; Ji, Hao; Schools, Gary P.; Cai, Chao; Pugacheva, Elena N.; Chen, Mengqian; Roninson, Igor B.; Broude, Eugenia V. Share Save
Mediator kinase inhibition reverses castration resistance of advanced cancer Li, Jing; Hilimire, Thomas A.; Liu, Yueying; Wang, Lili; Liang, Jiaxin; Gyorffy, Balazs; Sikirzhytski, Vitali; Ji, Hao; Zhang, Li; Cheng, Chen; Ding, Xiaokai; Kerr, Kendall R.; Dowling, Charles E.; Chumanevich, Alexander A.; Mack, Zachary T.; Schools, Gary P.; Lim, Chang-uk; Ellis, Leigh; Zi, Xiaolin; Porter, Donald C.; Broude, Eugenia V.; McInnes, Campbell; Wilding, George; Lilly, Michael B.; Roninson, Igor B.; Chen, Mengqian Share Save
CDK8/19-regulated transcriptional reprogramming: a druggable driver of castration-resistant prostate cancer Li, Jing; Hilimire, Thomas; Liu, Yueying; Wang, Lili; Liang, Jiaxin; Gyorffy, Balazs; Sikitzhytski, Vitali; Ji, Hao; Zhang, Li; Cheng, Chen; Ding, Xiaokai; Kerr, Kendall; Dowling, Charles; Schools, Gary; Lim, Chang-Uk; Braude, Eugenia; Wilding, George; Lilly, Michael; Roninson, Igor; Chen, Mengqian Share Save
CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins Chen, Mengqian; Li, Jing; Zhang, Li; Wang, Lili; Cheng, Chen; Ji, Hao; Altilia, Serena; Ding, Xiaokai; Cai, Guoshuai; Altomare, Diego; Shtutman, Michael; Byrum, Stephanie D.; Mackintosh, Samuel G.; Feoktistov, Alexey; Soshnikova, Nataliya; Mogila, Vladislav A.; Tatarskiy, Victor; Erokhin, Maksim; Chetverina, Darya; Prawira, Angga; Ni, Yi; Urban, Stephan; McInnes, Campbell; Broude, Eugenia, V; Roninson, Igor B. Share Save
Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes Kokinos, Elena K.; Tsymbal, Sergey A.; Galochkina, Anastasia V.; Bezlepkina, Svetlana A.; Nikolaeva, Julia V.; Vershinina, Sofia O.; Shtro, Anna A.; Tatarskiy, Victor V.; Shtil, Alexander A.; Broude, Eugenia V.; Roninson, Igor B.; Dukhinova, Marina Share Save
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Dual therapeutic targeting of CDK8/19 and mTOR in triple negative breast cancer Ding, Xiaokai; Ji, Hao; Sharko, Amanda C.; Loskutov, Juergen; Mack, Zachary; Myers, Jadyn; Chen, Mengqian; Pugacheva, Elena; Roninson, Igor; Broude, Eugenia Share Save
Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo Ding, Xiaokai; Sharko, Amanda C.; McDermott, Martina S. J.; Schools, Gary P.; Chumanevich, Alexander; Ji, Hao; Li, Jing; Zhang, Li; Mack, Zachary T.; Sikirzhytski, Vitali; Shtutman, Michael; Ivers, Laura; O'Donovan, Norma; Crown, John; Gyorffy, Balazs; Chen, Mengqian; Roninson, Igor B.; Broude, Eugenia, V Share Save
Preventing adaptive therapeutic resistance to CDK4/6 inhibition with CDK8/19 inhibitors Mack, Zachary; Yastrebova, Margarita; Khamidullina, Alvina; Sharko, Amanda; Ding, Xiaokai; Bowe, Stephan; Sashi, Nikitha; Safa, Samantha; Digsby, Kaitlyn; Eckstrom, Amanda; Sikirzhitski, Vitali; Lim, Chang-Uk; Tatarskiy, Victor; Roninson, Igor; Broude, Eugenia Share Save
A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics Zhang, Li; Cheng, Chen; Li, Jing; Wang, Lili; Chumanevich, Alexander A.; Porter, Donald C.; Mindich, Aleksei; Gorbunova, Svetlana; Roninson, Igor B.; Chen, Mengqian; McInnes, Campbell Share Save
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