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Ahmed A. Al‐Karmalawy

horus university

51H-index
232Paper Count
7.2KCitation Count
Published Papers 126
Publication Date
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Covalent Molecular Glues: Mechanisms, Design Principles, and Emerging Therapeutic Opportunities in Targeted Protein Degradation
errArchiv der Pharmazie
IF3.6
err2026-05-22
err0
PREAI
errAhmed A. Al-Karmalawy; Mohamed Ibrahim Attia; Tarek A. Yousef; Mohammed Bashar Al-Qazzan; Mohammed Al-Akeedi; Arwa Omar Al Khatib; Samia S. Hawas
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Discovery of Caralluma-derived pregnane glycosides as potent and selective cholinesterase inhibitors: integrated in silico and in vitro evaluation
errrsc adv.
IF0
err2026-05-15
err0
errOAAI
errAhmed A. Al-Karmalawy; Mohamed Ibrahim Attia; Radwan Alnajjar; Riham A. El-Shiekh; Arwa Omar Al Khatib; Tarek A. Yousef; Essam Abdel-Sattar
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Designing Telomerase Inhibitors for Cancer Therapy: Mechanistic Insights, Medicinal Chemistry Strategies, Challenges, and Future Directions
errArchiv der Pharmazie
IF3.6
err2026-05-12
err0
PREAI
errAhmed A. Al-Karmalawy; Mohamed Ibrahim Attia; Marwa Sharaky; Arwa Omar Al Khatib; Tarek A. Yousef; Samia S. Hawas
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Designing the Next Generation of Antibiotics: Structure, SAR, and Strategy in Medicinal Chemistry (2000-2025)
errMedicinal Research Reviews
IF11.6
err2026-05-01
err0
PREAI
errAl-Karmalawy, Ahmed A.; Al-Dakhil, Abdullah; Ashour, Nada A.; Yousef, Tarek A.; Mabrouk, Samar S.; Al Khatib, Arwa Omar; Hawas, Samia S.
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Integrated metabolite profiling and molecular docking reveal anti-aging potential of Clerodendrum infortunatum L. fractions
errScientific Reports
IF3.9
err2026-04-22
err0
errOAAI
errFatma Atef; Mostafa A. Abdelkawy; Basma M. Eltanany; Laura Pont; Ahmed A. Al-Karmalawy; Fernando Benavente; Inas Y. Younis; Asmaa M. Otify
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Antiviral activity and chemical characterization of Egyptian Ziziphus spina-christi against human respiratory viruses
errScientific Reports
IF3.9
err2026-04-19
err0
errOAAI
errAmany Elkhrsawy; Omnia Kutkat; Yassmin Moatasim; Mohamed S. Refaey; Ahmed A. Al-Karmalawy; Eman Elabd; Amr Keshta; Kamal Shaltout; Rabeh El-Shesheny
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Hybrid benzylidene thiazolidine-2; 4-diones as potent apoptosis-inducing anticancer agents: design-driven optimization; cytotoxic profiling; and mechanistic validation in prostate cancer
errrsc adv.
IF0
err2026-04-17
err0
errOAAI
errSaad Shaaban †; Samia S. Hawas †; Marwa Sharaky; Hussein Ba-Ghazal; Ayman Abo Elmaaty; Khadra B. Alomari; Mohamed Alaasar; Asma M. Elsharif; Fatema S. Alatawi; Mohamed Alaa Mohamed; Arwa Omar Al Khatib; Ahmed A. Al-Karmalawy
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Targeting the Menin–KMT2A Interface: Medicinal Chemistry Rules Governing Reversible, Covalent, and Degrader Inhibitors
errChemical Biology & Drug Design
IF3.3
err2026-04-04
err0
PREAI
errAhmed A. Al-Karmalawy; Mohamed E. Eissa; Tarek A. Yousef; Marwa Sharaky; Arwa Omar Al Khatib; Samia S. Hawas
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PTC-Assisted Chemoselective S-Alkylation of 5-Mercapto-1,3,4-Oxadiazol Derivative: Multi-Target Anticancer via EGFR, Telomerase, and Thymidylate Synthase Inhibition With Apoptosis Induction
errDrug Development Research
IF4.2
err2026-03-29
err0
PREAI
errZakaria, Asmaa; Al-Karmalawy, Ahmed A.; Hawas, Samia S.; Ali, Ali Khalil; Elsayed, Galal A.; Al Khatib, Arwa Omar; Abbass, Eslam M.
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Synthesis, characterization, molecular modelling, and antimicrobial evaluation of novel drug–polymer composites grafted with polyvinylpyrrolidone
errJournal of Molecular Structure
IF4.7
err2026-03-03
err0
PREAI
errZahraa Mokhtar; Mohamed E. Eissa; Mohammed Bashar Al-Qazzan; Violet Kasabri; Mohammed Al-Akeedi; Sana Hitur Awad; Tarek A. Yousef; Ahmed A. Al-Karmalawy
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Targeting cell cycle and apoptotic pathways with newly synthesized diselenide-linked imidazolone analogues with strong CDK6-targeting potential
errrsc adv.
IF0
err2026-02-05
err0
errOAAI
errMarwa Abdel-Motaal †; Saad Shaaban †; Samia S. Hawas †; Asma M. Elsharif; Marwa Sharaky; Fatema S. Alatawi; Mohamed E. Eissa; Arwa Omar Al Khatib; Hany M. Abd El-Lateef; Medhat Asem; Ahmed A. Al-Karmalawy
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Organoselenium-based Schiff bases and amidic acid derivatives as promising anticancer agents targeting breast cancer by downregulating BCL-2: design; synthesis; and biological evaluation
errrsc adv.
IF0
err2026-02-02
err0
errOAAI
errSaad Shaaban; Samia S. Hawas; Asma M. Elsharif; Marwa Sharaky; Hussein Ba-Ghazal; Mohamed Alaasar; Fatema S. Alatawi; Khadra B. Alomari; Mohamed E. Eissa; Arwa Omar Al Khatib; Radwan Alnajjar; Ahmed A. Al-Karmalawy
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Bridging mechanism and design: modern medicinal chemistry approaches to thymidylate synthase inhibitors
errrsc adv.
IF0
err2026-01-30
err0
errOAAI
errAhmed A. Al-Karmalawy; Mohamed E. Eissa; Tarek A. Yousef; Arwa Omar Al Khatib; Samia S. Hawas
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Editorial Expression of Concern: Bioactive fraction from Plumeria obtusa L. attenuates LPS‑induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF‑MS and molecular docking
errInflammopharmacology
IF5.3
err2025-12-03
err0
errOAAI
errYousra T. Eloutify; Riham A. El‑Shiekh; Khaled Meselhy Ibrahim; Ahmed R. Hamed; Ahmed A. Al‑Karmalawy; Aya A. Shokry; Yasmine H. Ahmed; Bharathi Avula; Kumar Katragunta; Ikhlas A. Khan; Meselhy R. Meselhy
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Multi-target design of fused cyclic pyrimidine-2-thione candidates as DNA intercalators and topoisomerase I/II inhibitors
errFuture Medicinal Chemistry
IF3.4
err2025-12-01
err0
PREAI
errKhalil, Mahmoud S.; Al-Karmalawy, Ahmed A.; Abo Elmaaty, Ayman; Elsayed, Galal A.; Hassan, A. M. A.
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Exploring the apoptosis-inducing potential of Syzygium cimini leaves in cancer treatment; LC-ESI-MS/MS analysis, biological assessments, and computational studies
errScientific African
IF3.3
err2025-11-24
err0
errOAAI
errAhmed A. Al-Karmalawy; Mohamed E. Eissa; Rehab F. Taher; Tarek A. Yousef; Arwa Omar Al Khatib; Marwa Sharaky; Radwan Alnajjar; Haidy A. Abbas
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Leveraging the Fragment Merging Approach for Synthetizing Novel Selanyl Phenyl Acetamide Thiazolidinedione Hybrids Endowed With Apoptotic Potential for Cancer Treatment
errDrug Development Research
IF4.2
err2025-11-17
err0
PREAI
errSaad Shaaban; Ayman Abo Elmaaty; Aya Yaseen Mahmood Alabdali; Hussein Ba-Ghazal; Marwa Sharaky; Mohamed Alaa Mohamed; Mai A. E. Mourad; Mohamed Alaasar; Fatema Suliman Alatawi; Tarek A. Yousef; Arwa Omar Al Khatib; Ahmed A. Al-Karmalawy
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Design and development of potent roflumilast analogues targeting PDE-4B: selectivity and pharmacokinetic insights
errBioorganic Chemistry
IF4.7
err2025-11-04
err0
PREAI
errAhmed M. Moussa; Heba Abdelrasheed Allam; Ahmed A. Al-Karmalawy; Abdelrahman K. Salem; Radwan Alnajjar; Sally T. Mahmoud; Marwa A. Fouad; Mohamed K. El-Ashrey
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Design; synthesis; and anticancer evaluation of novel pyrazole–thiophene hybrid derivatives as multitarget inhibitors of wild EGFR; mutant (T790M) EGFR; and VEGFR-2
errRSC Adv.
IF0
err2025-10-22
err0
errOAAI
errMohammed N. Sallam †; Ahmed A. Al-Karmalawy †; Eslam M. Abbass; Samia S. Hawas; Abeer M. El-Naggar; A. M. A. Hassan
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Comprehensive phytochemical mapping and biomedical evaluation of Lawsonia inermis L: a potential natural treatment for diabetic foot ulcers with wound healing and antimicrobial effects
errFitoterapia
IF2.6
err2025-10-17
err0
PREAI
errSafaa M. Kotb; Mai M. Farid; Ahmed A. Al-Karmalawy; Magdy A.H. Zahran; Briksam S. Mohamed; Abdelnaser A. Gadallah; Bishoy El-Aarag
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Research Directions

No research directions
Co-authors
Cooperation Journals
A
Alisdair R. Fernie
H-index: 170 · Papers: 1.7K
C
Claudiu T. Supuran
H-index: 152 · Papers: 4.2K
R
Richard J. Webby
H-index: 106 · Papers: 763
T
Túlio de Oliveira
H-index: 84 · Papers: 536
D
Darren P. Martin
H-index: 77 · Papers: 394
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