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D

David R. Spring

university of cambridge

67H-index
544Paper Count
2.0WCitation Count
Published Papers 146
Publication Date
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Recent advances in antibody–drug conjugates
errCurrent Opinion in Chemical Biology
IF6.1
err2026-07-16
err0
errOAAI
errJack D. Sydenham; Thomas Wharton; David R. Spring
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errSave
Peptide Marriages: Modular Assembly of Multi-Agonist Therapeutics
errChemistry – A European Journal
IF0
err2026-06-18
err0
errOAAI
errKristina A. Kostadinova; Jan L. Venne; Sona Krajcovicova; James Dodgson; Wouter F. J. Hogendorf; Thomas E. Nielsen; David Hymel; Hannah Bolt; Andie Collinson; Jason Day; Jefferson Revell; David R. Spring
errShare
errSave
On-resin assembly of cysteine-reactive linkers for controlled site-selective antibody bioconjugation
errNature Protocols
IF16
err2026-06-09
err0
PREAI
errSona Krajcovicova; Thomas Wharton; David R. Spring
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errSave
Boosting Peptide Half-Life: Enabling Efficient Generation of Fc-Peptide Conjugates
errchem. sci.
IF0
err2026-05-29
err0
errOAAI
errMahri Park; Friederike M. Dannheim; Monika A. Papworth; Richard Kay; Elpida Tsonou; Daniel Trajkovski; Stephen J Walsh; Daniel Hovdal; Thomas Wharton; Anne-Chloe Nassoy; Jeremy Parker; David R Spring
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errSave
Towards the targeted protein degradation of CK2: design and synthesis of CAM4066-based PROTACs
errBeilstein Journal of Organic Chemistry
IF2.1
err2026-04-22
err0
PREAI
errDay-Riley, Sophie; Krajcovicova, Sona; Sokhal, Aryaman Raj; Venne, Jan L.; Brear, Paul; Hyvonen, Marko; Whitehurst, Benjamin C.; Carroll, Jason S.; Spring, David R.
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errSave
Bismuth Bicycles
errJournal of Peptide Science
IF1.8
err2026-03-01
err0
PREAI
errVoss, Saan; Sagar, Amin; Tiberghien, Arnaud; Hughes, Richard J. L.; Chen, Liuhong; Rioja, Inmaculada; Frigerio, Mark; Skynner, Michael J.; Spring, David R.
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errSave
MMP-Cleavable Linker Platform for Tumour-Responsive Homo- and Heterobivalent Antibody-Drug Conjugates
errChem. Sci.
IF0
err2025-12-04
err0
errOAAI
errAndrew James Counsell; Stephen J Walsh; Nicola Ashman; Mahri Park; Friederike M. Dannheim; Thomas A King; Thomas Wharton; Jason S Carroll; David R Spring
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errSave
Recent progress towards catalytic asymmetric construction of inherently chiral scaffolds
errChem. Soc. Rev.
IF0
err2025-10-20
err0
errOAAI
errKai Zhu; David R. Spring; Bing-Feng Shi; Fengzhi Zhang
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errSave
Exploiting the Cryptic αD Pocket of Casein Kinase 2α (CK2α) to Deliver Highly Potent and Selective Type 1 Inhibitors
errJournal of Medicinal Chemistry
IF6.8
err2025-10-14
err0
errOAAI
errPaul A. Glossop; Paul Brear; Susanne Wright; Neil Flanagan; Melanie S. Glossop; Charlotte A. L. Lane; Richard P. Butt; David R. Spring; Marko Hyvönen; Darren Cawkill
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errSave
Towards a glutathione-cleavable azobenzene linker for antibody-drug conjugates
errCHEMICAL COMMUNICATIONS
IF4.2
err2025-10-01
err0
PREAI
errKapun, Mia; Patel, Roshan; Park, Mahri; Perez-Areales, F. Javier; Kostadinova, Kristina A.; Wharton, Thomas; Carroll, Jason S.; Spring, David R.
errShare
errSave
β-Lactamase cleavable antimicrobial peptide–drug conjugates
errChem. Sci.
IF7.4
err2025-09-19
err0
errOAAI
errTomas Deingruber; Josephine S. Gaynord; Bee Ha Gan; Kristina A. Kostadinova; Thomas J. O'Brien; Yaw Sing Tan; Jeremy S. Parker; Thomas A. Hunt; Jason S. Carroll; Martin Welch; David R. Spring
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errSave
Pseudomonas aeruginosa PfpI is a methylglyoxalase
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-04-01
err0
errOAAI
errGrimm, Larson; Wijaya, Andre; Askenasy, Isabel; Nazeer, Rahan Rudland; Seki, Hikaru; Brear, Paul D.; Figueroa, Wendy; Spring, David R.; Welch, Martin
errShare
errSave
Methods for the Generation of Single-Payload Antibody-Drug Conjugates
errCHEMMEDCHEM
IF3.4
err2025-03-01
err0
PREAI
errWharton, Thomas; Spring, David R.
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errSave
The 2-methylcitrate cycle and the glyoxylate shunt in Pseudomonas aeruginosa are linked through enzymatic redundancy
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-02-01
err0
errOAAI
errWijaya, Andre J.; Dolan, Stephen K.; Kohlstedt, Michael; Glaeser, Lars; Brear, Paul; Geddis, Stephen; Wittmann, Christoph; Spring, David R.; Welch, Martin
errShare
errSave
Advances in the Release of Amide-Containing Molecules
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2025-01-28
err0
PREAI
errWharton, Thomas; Spring, David R.
errShare
errSave
A platform for SpyCatcher conjugation to native antibodies
errCHEMICAL SCIENCE
IF7.4
err2025-01-01
err0
errOAAI
errKrajcovicova, Sona; Wharton, Thomas; Driscoll, Claudia L.; King, Thomas A.; Howarth, Mark R.; Spring, David R.
errShare
errSave
Novel immunotherapeutics against LGR5 to target multiple cancer types (vol 16, pg 2233, 2024)
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-09-25
err1
errOAAI
errChen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M.; Beke, Flavio; Walsh, Stephen J.; Ashman, Nicola; O'Brien, Louise; Fard, Amir Rafati; Ghodsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J.; Hoare, Matthew; Mair, Richard; Serrao, Eva; Brenton, James D.; Garcia-Gimenez, Alicia; Richardson, Simon E.; Huntly, Brian; Spring, David R.; Skjoedt, Mikkel-Ole; Skjodt, Karsten; de la Roche, Marc; de la Roche, Maike
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errSave
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-27
err0
errOAAI
errStockwell, Simon R.; Scott, Duncan E.; Fischer, Gerhard; Guarino, Estrella; Rooney, Timothy P. C.; Feng, Tzu-Shean; Moschetti, Tommaso; Srinivasan, Rajavel; Alza, Esther; Asteian, Alice; Dagostin, Claudio; Alcaide, Anna; Rocaboy, Mathieu; Blaszczyk, Beata; Higueruelo, Alicia; Wang, Xuelu; Rossmann, Maxim; Perrior, Trevor R.; Blundell, Tom L.; Spring, David R.; Mckenzie, Grahame; Abell, Chris; Skidmore, John; Venkitaraman, Ashok R.; Hyvonen, Marko
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errSave
Novel immunotherapeutics against LGR5 to target multiple cancer types
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-08-21
err1
PREAI
errChen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M.; Beke, Flavio; Walsh, Stephen J.; Ashman, Nicola; O'Brien, Louise; Rafati Fard, Amir; Godsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J.; Hoare, Matthew; Mair, Richard; Serrao, Eva; Brenton, James D.; Garcia-Gimenez, Alicia; Richardson, Simon E.; Huntly, Brian; Spring, David R.; Skjoedt, Mikkel-Ole; Skjodt, Karsten; de la Roche, Marc; de la Roche, Maike
errShare
errSave
Towards the Targeted Protein Degradation of PRMT1
errCHEMMEDCHEM
IF3.4
err2024-06-20
err9
errOAAI
errMartin, Poppy L.; Perez-Areales, Francisco Javier; Rao, Shalini V.; Walsh, Stephen J.; Carroll, Jason S.; Spring, David R.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Juyoung Yoon
H-index: 145 · Papers: 750
D
David P. Lane
H-index: 136 · Papers: 959
K
Kwang S. Kim
H-index: 122 · Papers: 1.1K
T
Tom L. Blundell
H-index: 112 · Papers: 736
W
Wilhelm T. S. Huck
H-index: 101 · Papers: 465
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