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Structural determinants for activation of the Tau kinase CDK5 by the serotonin receptor 5-HT7R Ackmann, Jana; Bruege, Alina; Gotina, Lizaveta; Lim, Sungsu; Jahreis, Kathrin; Vollbrecht, Anna-Lena; Kim, Yun Kyung; Pae, Ae Nim; Labus, Josephine; Ponimaskin, Evgeni Share Save
Highly potent and selective PPAR6 agonist reverses memory deficits in mouse models of Alzheimer's disease Kim, Hyeon Jeong; Kim, Haelee; Song, Jaeyoung; Hong, Jun Young; Lee, Elijah Hwejin; Londhe, Ashwini M.; Choi, Ji Won; Park, Sun Jun; Oh, Eunseok; Yoon, Heeseok; Hwang, Hoosang; Hahn, Dongyup; Jung, Kyungjin; Kwon, Sugyeong; Kadayat, Tara Man; Ma, Min Jung; Joo, Jeongmin; Kim, Jina; Bae, Jae Hyun; Hwang, Hayoung; Pae, Ae Nim; Cho, Sung Jin; Park, Jong-Hyun; Chin, Jungwook; Kang, Heonjoong; Park, Ki Duk Share Save
NeuM: A Neuron-Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin-Mediated Endocytosis in Primary Neurons Sung, Yoonsik; Gotina, Lizaveta; Kim, Kyu Hyeon; Lee, Jung Yeol; Shin, Seulgi; Aziz, Hira; Kang, Dong Min; Liu, Xiao; Hong, Na-Kyeong; Lee, Hong-Guen; Lee, Jun-Seok; Ku, Hyeyeong; Jeong, Cherlhyun; Pae, Ae Nim; Lim, Sungsu; Chang, Young-Tae; Kim, Yun Kyung Share Save
Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants Lee, Elliot H.; Park, Jung-eun; Gotina, Lizaveta; Han, Young-Eun; Viswanath, Ambily Nath Indu; Yoo, Seonguk; Moon, Bongjin; Hwang, Jin-Young; Park, Woo Kyu; Cho, Yoonjeong; Song, Chiman; Min, Sun-Joon; Hwang, Eun Mi; Lee, Hyunbeom; Pae, Ae Nim; Roh, Eun Joo; Oh, Soo-Jin Share Save
Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in TauP301L-BiFC mice Lim, Sungsu; Shin, Seulgi; Sung, Yoonsik; Lee, Ha Eun; Kim, Kyu Hyeon; Song, Ji Yeon; Lee, Gwan-Ho; Aziz, Hira; Lukianenko, Nataliia; Kang, Dong Min; Boesen, Nicolette; Jeong, Hyeanjeong; Abdildinova, Aizhan; Lee, Junghee; Yu, Byung-Yong; Lim, Sang Min; Lee, Jun-Seok; Ryu, Hoon; Pae, Ae Nim; Kim, Yun Kyung Share Save
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Highly Potent, Selective, and Competitive Indole-Based MAO-B Inhibitors Protect PC12 Cells against 6-Hydroxydopamine- and Rotenone-Induced Oxidative Stress Elsherbeny, Mohamed H.; Kim, Jushin; Gouda, Noha A.; Gotina, Lizaveta; Cho, Jungsook; Pae, Ae Nim; Lee, Kyeong; Park, Ki Duk; Elkamhawy, Ahmed; Roh, Eun Joo Share Save
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion Kim, Tai Young; Jeon, Sangeun; Jang, Youngho; Gotina, Lizaveta; Won, Joungha; Ju, Yeon Ha; Kim, Sunpil; Jang, Minwoo Wendy; Won, Woojin; Park, Mingu Gordon; Pae, Ae Nim; Han, Sunkyu; Kim, Seungtaek; Lee, C. Justin Share Save
Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model Hwang, Yu Jin; Hyeon, Seung Jae; Kim, Younghee; Lim, Sungsu; Lee, Min Young; Kim, Jieun; Londhe, Ashwini M.; Gotina, Lizaveta; Kim, Yunha; Pae, Ae Nim; Cho, Yong Seo; Seong, Jihye; Seo, Hyemyung; Kim, Yun Kyung; Choo, Hyunah; Ryu, Hoon; Min, Sun-Joon Share Save
The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents Kim, TaeHun; Morshed, Mohammad N.; Londhe, Ashwini M.; Lim, Ji W.; Lee, Ha E.; Cho, Suengmok; Cho, Sung J.; Hwang, Hayoung; Lim, Sang M.; Lee, Jae Y.; Lee, Jiyoun; Pae, Ae N. Share Save
Discovery ofN-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B Elkamhawy, Ahmed; Paik, Sora; Kim, Hyeon Jeong; Park, Jong-Hyun; Londhe, Ashwini M.; Lee, Kyeong; Pae, Ae Nim; Park, Ki Duk; Roh, Eun Joo Share Save
PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates Choi, Ji-Woo; Ju, Yeon Ha; Choi, Yunsook; Hyeon, Seung Jae; Gadhe, Changdev G.; Park, Jong-Hyun; Kim, Mun Seok; Baek, Seungyeop; Kim, YoungSoo; Park, Ki Duk; Pae, Ae Nim; Ryu, Hoon; Lee, C. Justin; Cho, Bong Rae Share Save
Visualization of soluble tau oligomers in TauP301L-BiFC transgenic mice demonstrates the progression of tauopathy Shin, Seulgi; Kim, Dohee; Song, Ji Yeon; Jeong, Hyeanjeong; Hyeon, Seung Jae; Kowall, Neil W.; Ryu, Hoon; Pae, Ae Nim; Lim, Sungsu; Kim, Yun Kyung Share Save
Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents Elkamhawy, Ahmed; Kim, Nam Youn; Hassan, Ahmed H. E.; Park, Jung-eun; Paik, Sora; Yang, Jeong-Eun; Oh, Kwang-Seok; Lee, Byung Ho; Lee, Mi Young; Shin, Kye Jung; Pae, Ae Nim; Lee, Kyung-Tae; Roh, Eun Joo Share Save
CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual Yun, Yeomin; Hong, Sung-Ah; Kim, Ka-Kyung; Baek, Daye; Lee, Dongsu; Londhe, Ashwini M.; Lee, Minhyung; Yu, Jihyeon; McEachin, Zachary T.; Bassell, Gary J.; Bowser, Robert; Hales, Chadwick M.; Cho, Sung-Rae; Kim, Janghwan; Pae, Ae Nim; Cheong, Eunji; Kim, Sangwoo; Boulis, Nicholas M.; Bae, Sangsu; Ha, Yoon Share Save
A novel chalcone derivative as Nrf2 activator attenuates learning and memory impairment in a scopolamine-induced mouse model Kim, Hyeon Jeong; Jang, Bo Ko; Park, Jong-Hyun; Choi, Ji Won; Park, Sun Jun; Byeon, Seong Rim; Pae, Ae Nim; Lee, Yang Sup; Cheong, Eunji; Park, Ki Duk Share Save
Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy Kim, Byung-Hak; Lee, Haeri; Song, Yeonghun; Park, Joon-Suk; Gadhe, Changdev G.; Choi, Jiwon; Lee, Chung-Gi; Pae, Ae Nim; Kim, Sanghee; Ye, Sang-Kyu Share Save
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