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Andreas M. Kany

helmholtz centre for infection research

15H-index
71Paper Count
591Citation Count
Published Papers 36
Publication Date
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Multiparameter Optimization of Pseudomonas aeruginosa Elastase Inhibitors for Systemic Administration
errJournal of Medicinal Chemistry
IF6.8
err2026-02-05
err0
errOAAI
errAhmed S. Abdelsamie; Jelena Konstantinović; Andreas M. Kany; Christian Schütz; Dominik Kolling; Samira Speicher; Andreas Klein; Roya Shafiei; Mélodie Bouté; Katharina Mundry; Yu Mi Park; Brigitta Loretz; Rolf Müller; Jean-Michel Sallenave; Claus-Michael Lehr; Jesko Koehnke; Katharina Rox; Jörg Haupenthal; Anna K. H. Hirsch
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Microbial Cross-Talk: Unlocking the Cytochalasin Diversity from a Termite-Associated Xylaria
errJACS Au
IF8.7
err2025-12-21
err0
errOAAI
errMarie Dayras; Yaming Liu; Rebecca Kochems; Martinus de Kruijff; Sven Balluff; Sari Rasheed; Andreas M. Kany; Jennifer Herrmann; Sebastian Götze; Bernd Morgenstern; N’Golo A. Koné; Michael Poulsen; Rolf Müller; Christine Beemelmanns
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Toward Anti-Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen
errCHEMMEDCHEM
IF3.4
err2025-11-01
err0
errOAAI
errBerwanger, Aylin; Stein, Saskia Catherina; Brandner, Sarah; Kany, Andreas Martin; Heinz, Sebastian; Loretz, Brigitta; Lehr, Claus-michael; Hirsch, Anna Katharina Herta; Lermyte, Frederik; Schulz, Thomas Friedrich; Empting, Martin
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Engineering an Artificial Myxopyronin Derivative with Enhanced Metabolic Stability via Mutasynthesis
errJACS AU
IF8.7
err2025-11-01
err0
PREAI
errKiefer, Alexander F.; Voltz, Alexander; Scherzer, Domen; Rebersek, Roman; Kany, Andreas M.; Prosser, Gareth; Neuber, Markus; Reiling, Norbert; Hirsch, Anna K. H.; Muller, Rolf
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Design, Synthesis, and Biological Evaluation of Mono- and Diamino-Substituted Squaramide Derivatives as Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthase
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-11-01
err0
PREAI
errPalme, Paul R.; Grover, Shipra; Abdelaziz, Rana; Mann, Lea; Kany, Andreas M.; Ouologuem, Lina; Bartel, Karin; Sonnenkalb, Lindsay; Reiling, Norbert; Hirsch, Anna K. H.; Schnappinger, Dirk; Rubinstein, John L.; Imming, Peter; Richter, Adrian
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Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets
errCELL CHEMICAL BIOLOGY
IF7.2
err2025-04-01
err0
errOAAI
errDeschner, Felix; Mostert, Dietrich; Daniel, Jan-Martin; Voltz, Alexander; Schneider, Dana Carina; Khangholi, Navid; Bartel, Jueurorgen; de Carvalho, Lais Pessanha; Brauer, Madita; Gorelik, Tatiana E.; Kleeberg, Christian; Risch, Timo; Haeckl, F. P. Jake; Benitez, Laura Herraiz; Andreas, Anastasia; Kany, Andreas Martin; Jezequel, Gwenaelle; Hofer, Walter; Muesken, Mathias; Held, Jana; Bischoff, Markus; Seemann, Ralf; Broetz-Oesterhelt, Heike; Schneider, Tanja; Sieber, Stephan; Mueller, Rolf; Herrmann, Jennifer
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From Dyrk1A inhibitors to a novel class of antiviral agents: Targeting Enterovirus EV-A71 with 2-aryl-substituted thiophene scaffolds
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-04-01
err0
PREAI
errKeddis, Parthiena M.; Tu, Tuong-Khanh My; Scherer, Hugo; Kany, Andreas M.; Hafez, Donia E.; Darwish, Sarah S.; Abadi, Ashraf H.; Hirsch, Anna K. H.; Engel, Matthias; Hamed, Mostafa M.; Horng, Jim-Tong; Abdel-Halim, Mohammad
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Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model
errADVANCED SCIENCE
IF14.1
err2025-02-19
err0
errOAAI
errKiefer, AF; Schütz, C; Englisch, CN; Kolling, D; Speicher, S; Kany, AM; Shafiei, R; Wadood, NA; Aljohmani, A; Wirschem, N; Jumde, RP; Klein, A; Sikandar, A; Park, YM; Krasteva-Christ, G; Yildiz, D; Abdelsamie, AS; Rox, K; Köhnke, J; Müller, R; Bischoff, M; Haupenthal, J; Hirsch, AKH
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Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assembly
errCHEMICAL SCIENCE
IF7.4
err2025-01-01
err0
errOAAI
errMostert, Dietrich; Braun, Josef; Zimmerman, Matthew D.; Engelhart, Curtis A.; Berndl, Sara; Quoika, Patrick K.; Kany, Andreas M.; Proietto, Julianna; Penalva-Lopez, Suyapa; Wallach, Joshua B.; Hirsch, Anna K. H.; Zacharias, Martin; Schnappinger, Dirk; Dartois, Veronique; Sieber, Stephan A.
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Structure Revision of Halisphingosine A via Total Synthesis and Bioactivity Studies
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-11-21
err0
errOAAI
errSauer, Maria; Kany, Andreas M.; Goetze, Sebastian; Mueller, Rolf; Beemelmanns, Christine
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errSave
In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens
errACS INFECTIOUS DISEASES
IF3.8
err2024-11-20
err1
errOAAI
errKany, Andreas M.; Fries, Franziska; Seyfert, Carsten E.; Porten, Christoph; Deckarm, Selina; Ortiz, Mariia Chacon; Dubarry, Nelly; Vaddi, Swapna; Grosse, Miriam; Bernecker, Steffen; Sandargo, Birthe; Muller, Alison V.; Bacque, Eric; Stadler, Marc; Herrmann, Jennifer; Muller, Rolf
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Thermo-amplifier circuit in probiotic E. coli for stringently temperature-controlled release of a novel antibiotic
errJOURNAL OF BIOLOGICAL ENGINEERING
IF6.5
err2024-11-12
err1
errOAAI
errDey, Sourik; Seyfert, Carsten E.; Fink-Straube, Claudia; Kany, Andreas M.; Mueller, Rolf; Sankaran, Shrikrishnan
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Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err0
errOAAI
errAbdelsamie, Ahmed S.; Hamed, Mostafa M.; Schuetz, Christian; Roehrig, Teresa; Kany, Andreas M.; Schmelz, Stefan; Blankenfeldt, Wulf; Hirsch, Anna K. H.; Hartmann, Rolf W.; Empting, Martin
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Targeting Plasmodium falciparum IspD in the Methyl-D-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-20
err1
errOAAI
errWillocx, Daan; Bizzarri, Lorenzo; Alhayek, Alaa; Kannan, Deepika; Bravo, Patricia; Illarionov, Boris; Rox, Katharina; Lohse, Jonas; Fischer, Markus; Kany, Andreas M.; Hahne, Hannes; Rottmann, Matthias; Witschel, Matthias; Odom John, Audrey; Hamed, Mostafa M.; Diamanti, Eleonora; Hirsch, Anna K. H.
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Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-20
err0
errOAAI
errMielniczuk, Sebastian; Hoff, Katharina; Baselious, Fady; Li, Yunqi; Haupenthal, Joerg; Kany, Andreas M.; Riedner, Maria; Rohde, Holger; Rox, Katharina; Hirsch, Anna K. H.; Krimm, Isabelle; Sippl, Wolfgang; Holl, Ralph
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Target-Directed Dynamic Combinatorial Chemistry Affords Binders of Mycobacterium tuberculosis IspE
errACS OMEGA
IF4.3
err2024-08-29
err1
errOAAI
errBraun-Cornejo, Maria; Ornago, Camilla; Sonawane, Vidhisha; Haupenthal, Joerg; Kany, Andreas M.; Diamanti, Eleonora; Jezequel, Gwenaelle; Reiling, Norbert; Blankenfeldt, Wulf; Maas, Peter; Hirsch, Anna K. H.
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Functionalization of Chlorotonils: Dehalogenil as Promising Lead Compound for In Vivo Application
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-04-03
err1
errOAAI
errHofer, Walter; Deschner, Felix; Jezequel, Gwenaelle; Pessanha de Carvalho, Lais; Abdel-Wadood, Noran; Paetzold, Linda; Bernecker, Steffen; Morgenstern, Bernd; Kany, Andreas M.; Grosse, Miriam; Stadler, Marc; Bischoff, Markus; Hirsch, Anna K. H.; Held, Jana; Herrmann, Jennifer; Mueller, Rolf
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Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-04-01
err6
errOAAI
errAl-Saad, Omar M.; Gabr, Moustafa; Darwish, Sarah S.; Rullo, Mariagrazia; Pisani, Leonardo; Miniero, Daniela Valeria; Liuzzi, Grazia Maria; Kany, Andreas M.; Hirsch, Anna K. H.; Abadi, Ashraf H.; Engel, Matthias; Catto, Marco; Abdel-Halim, Mohammad
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Isocyanides inhibit bacterial pathogens by covalent targeting of essential metabolic enzymes
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err0
errOAAI
errGeissler, Alexandra; Junca, Howard; Kany, Andreas M.; Daumann, Lena J.; Hirsch, Anna K. H.; Pieper, Dietmar H.; Sieber, Stephan A.
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New Genetically Engineered Derivatives of Antibacterial Darobactins Underpin Their Potential for Antibiotic Development
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-11-21
err9
errOAAI
errSeyfert, Carsten E.; Mueller, Alison V.; Walsh, Danica J.; Birkelbach, Joy; Kany, Andreas M.; Porten, Christoph; Yuan, Biao; Krug, Daniel; Herrmann, Jennifer; Marlovits, Thomas C.; Hirsch, Anna K. H.; Mueller, Rolf
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Research Directions

No research directions
Co-authors
Cooperation Journals
C
Claus‐Michael Lehr
H-index: 95 · Papers: 629
R
Rolf Müller
H-index: 94 · Papers: 1.2K
T
Tim Sparwasser
H-index: 82 · Papers: 351
T
Thomas F. Schulz
H-index: 79 · Papers: 547
R
Robert Bals
H-index: 74 · Papers: 916
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