Andreas O. Frank - Publications, H-index & Citations

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Andreas O. Frank

novartis

30H-index

155Paper Count

3.0KCitation Count

Published Papers 31

Publication Date

Targeted Transcriptional Repression by Induced Proximity

ACS Central Science

IF10.4

2026-06-11

OAAI

Christian E. Stieger; Xinru Chen; Christina C. Kuismi; Dustin Dovala; Daniel Fuller; Andreas O. Frank; Mikias Woldegiorgis; Megan Bruce-Smythe; Fabian Wu; Nicolas Pizzato; Jeffrey McKenna; Cory Johannessen; Barna D. Fodor; Markus Schirle; Daniel K. Nomura

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Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-09-27

OAAI

Barkan, David T.; Garland, Keira; Zhang, Lei; Eastman, Richard T.; Hesse, Matthew; Knapp, Mark; Ornelas, Elizabeth; Tang, Jenny; Cortopassi, Wilian Augusto; Wang, Yu; King, Frederick; Jia, Weiping; Nguyen, Zachary; Frank, Andreas O.; Chan, Ryan; Fang, Eric; Fuller, Daniel; Busby, Scott; Carias, Heidi; Donahue, Kristine; Tandeske, Laura; Diagana, Thierry T.; Jarrousse, Nadine; Moser, Heinz; Sarko, Christopher; Dovala, Dustin; Moquin, Stephanie; Marx, Vanessa M.

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Improving the Emergency Management of Unstable Ankle Fractures in a District General Hospital: A Quality Improvement Project

BRITISH JOURNAL OF SURGERY

IF8.7

2023-08-30

OAAI

Frank, A.; King, A.; Cunnington, R.; Bradman, H.

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Rational Chemical Design of Molecular Glue Degraders (vol 9, pg 915, 2023)

ACS CENTRAL SCIENCE

IF10.4

2023-07-21

OAAI

Toriki, Ethan S.; Papatzimas, James W.; Nishikawa, Kaila; Dovala, Dustin; Frank, Andreas O.; Hesse, Matthew J.; Dankova, Daniela; Song, Jae-Geun; Bruce-Smythe, Megan; Struble, Heidi; Garcia, Francisco J.; Brittain, Scott M.; Kile, Andrew C.; McGregor, Lynn M.; McKenna, Jeffrey M.; Tallarico, John A.; Schirle, Markus; Nomura, Daniel K.

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Rational Chemical Design of Molecular Glue Degraders

ACS CENTRAL SCIENCE

IF10.4

2023-04-11

OAAI

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Deubiquitinase-targeting chimeras for targeted protein stabilization

NATURE CHEMICAL BIOLOGY

IF13.7

2022-02-24

160

OAAI

Henning, Nathaniel J.; Boike, Lydia; Spradlin, Jessica N.; Ward, Carl C.; Liu, Gang; Zhang, Erika; Belcher, Bridget P.; Brittain, Scott M.; Hesse, Matthew J.; Dovala, Dustin; McGregor, Lynn M.; Misiolek, Rachel Valdez; Plasschaert, Lindsey W.; Rowlands, David J.; Wang, Feng; Frank, Andreas O.; Fuller, Daniel; Estes, Abigail R.; Randal, Katelyn L.; Panidapu, Anoohya; McKenna, Jeffrey M.; Tallarico, John A.; Schirle, Markus; Nomura, Daniel K.

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Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-02-17

PREAI

Han, Wooseok; Ma, Xiaolei; Balibar, Carl J.; Rath, Christopher M. Baxter; Benton, Bret; Bermingham, Alun; Casey, Fergal; Chie-Leon, Barbara; Cho, Min-Kyu; Frank, Andreas O.; Frommlet, Alexandra; Ho, Chi-Min; Lee, Patrick S.; Li, Min; Lingel, Andreas; Ma, Sylvia; Merritt, Hanne; Ornelas, Elizabeth; De Pascale, Gianfranco; Prathapam, Ramadevi; Prosen, Katherine R.; Rasper, Dita; Ruzin, Alexey; Sawyer, William S.; Shaul, Jacob; Shen, Xiaoyu; Shia, Steven; Steffek, Micah; Subramanian, Sharadha; Vo, Jason; Wang, Feng; Wartchow, Charles; Uehara, Tsuyoshi

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A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses

ELIFE

IF0

2020-01-21

OAAI

Kane, Joshua R.; Fong, Susan; Shaul, Jacob; Frommlet, Alexandra; Frank, Andreas O.; Knapp, Mark; Bussiere, Dirksen E.; Kim, Peter; Ornelas, Elizabeth; Cuellar, Carlos; Hyrina, Anastasia; Abend, Johanna R.; Wartchow, Charles A.

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Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex (vol 85, pg 231, 2019)

NATURE CHEMICAL BIOLOGY

IF13.7

2020-01-15

OAAI

Bussiere, Dirksen E.; Xie, Lili; Srinivas, Honnappa; Shu, Wei; Burke, Ashley; Be, Celine; Zhao, Junping; Godbole, Adarsh; King, Dan; Karki, Rajeshri G.; Hornak, Viktor; Xu, Fangmin; Cobb, Jennifer; Carte, Nathalie; Frank, Andreas O.; Frommlet, Alexandra; Graff, Patrick; Knapp, Mark; Fazal, Aleem; Okram, Barun; Jiang, Songchun; Michellys, Pierre-Yves; Beckwith, Rohan; Voshol, Hans; Wiesmann, Christian; Solomon, Jonathan M.; Paulk, Joshiawa

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Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

NATURE CHEMICAL BIOLOGY

IF13.7

2019-12-09

165

PREAI

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First Crystal Structure of a Nonstructural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein

JOURNAL OF VIROLOGY

IF3.8

2019-07-01

OAAI

Proudfoot, Andrew; Hyrina, Anastasia; Holdorf, Meghan; Frank, Andreas O.; Bussiere, Dirksen

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Helicobacter-negative gastritis: polymerase chain reaction for Helicobacter DNA is a valuable tool to elucidate the diagnosis

ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IF6.7

2016-02-17

OAAI

Kiss, S.; Zsikla, V.; Frank, A.; Willi, N.; Cathomas, G.

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Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication ProteinA

CHEMMEDCHEM

IF3.4

2016-01-08

OAAI

Patrone, James D.; Pelz, Nicholas F.; Bates, Brittney S.; Souza-Fagundes, Elaine M.; Vangamudi, Bhavatarini; Camper, Demarco V.; Kuznetsov, Alexey G.; Browning, Carrie F.; Feldkamp, Michael D.; Frank, Andreas O.; Gilston, Benjamin A.; Olejniczak, Edward T.; Rossanese, Olivia W.; Waterson, Alex G.; Chazin, Walter J.; Fesik, Stephen W.

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cis-Peptide Bonds: A Key for Intestinal Permeability of Peptides?

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2015-09-04

PREAI

Marelli, Udaya Kiran; Ovadia, Oded; Frank, Andreas Oliver; Chatterjee, Jayanta; Gilon, Chaim; Hoffman, Amnon; Kessler, Horst

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Discovery of probes to evaluate the disruption of the protein-protein interactions mediated by RPA70N

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Waterson, Alex G.; Kennedy, Phillip; Patrone, James D.; Pelz, Nicholas F.; Frank, Andreas O.; Vangamudi, Bhavatarini; Camper, DeMarco V.; Souza-Fagundes, Elaine M.; Feldkamp, Michael D.; Olejniczak, Edward T.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W.

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Diphenylpyrazoles as Replication Protein A Inhibitors

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2014-12-02

OAAI

Waterson, Alex G.; Kennedy, J. Phillip; Patrone, James D.; Pelz, Nicholas F.; Feldkamp, Michael D.; Frank, Andreas O.; Vangamudi, Bhavatarini; Souza-Fagundes, Elaine M.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W.

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Optimization of a potent stapled helix peptide that binds to Replication Protein A

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Waterson, Alex G.; Frank, Andreas O.; Vandgamudi, Bhavatarini; Feldkamp, Michael D.; Souza-Fagundes, Elaine M.; Luzwick, Jessica W.; Cortez, David; Olejniczak, Edward T.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W.

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Receptor-Bound Conformation of Cilengitide Better Represented by Its Solution-State Structure than the Solid-State Structure

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2014-09-22

PREAI

Marelli, Udaya Kiran; Frank, Andreas O.; Wahl, Bernhard; La Pietra, Valeria; Novellino, Ettore; Marinelli, Luciana; Herdtweck, Eberhardt; Groll, Michael; Kessler, Horst

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Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-02-19

OAAI

Frank, Andreas O.; Vangamudi, Bhavatarini; Feldkamp, Michael D.; Souza-Fagundes, Elaine M.; Luzwick, Jessica W.; Cortez, David; Olejniczak, Edward T.; Waterson, Alex G.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W.

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Discovery of a Potent Inhibitor of Replication Protein A Protein- Protein Interactions Using a Fragment-Linking Approach

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-11-11

OAAI

Frank, Andreas O.; Feldkamp, Michael D.; Kennedy, J. Philip; Waterson, Alex G.; Pelz, Nicholas F.; Patrone, James D.; Vangamudi, Bhavatarini; Camper, DeMarco V.; Rossanese, Olivia W.; Chazin, Walter J.; Fesik, Stephen W.

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Research Directions