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Jeffrey A. Medin

medical college of wisconsin

45H-index
283Paper Count
7.6KCitation Count
Published Papers 130
Publication Date
Reduced-intensity conditioning in LV-mediated gene therapy for Fabry disease targeting HSPCs
err2025-08-13
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PREAI
errAneal Khan; Dwayne L. Barber; Ronan Foley; Armand Keating; Michael L. West; Jeffrey A. Medin
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Fabry disease biomarker evaluation during a five-year gene therapy clinical trial
err2025-02-01
err0
PREAI
errAuray-Blais, Christiane; Lavoie, Pamela; Martineau, Tristan; Rupar, Tony; Barber, Dwayne L.; Keating, Armand; Foley, Ronan; Khan, Aneal; West, Michael L.; Medin, Jeffrey A.
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Lentiviral gene therapy for Fabry disease-5 Year end of study analysis for the FACTS trial
err2025-02-01
err0
PREAI
errKhan, Aneal; Barber, Dwayne; Rupar, Tony; Auray-Blais, Christiane; Fraser, Graeme; Fowler, Daniel; Foley, Ronan; Keating, Armand; West, Michael L.; Medin, Jeffrey A.
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Lentivirus-mediated gene therapy for Fabry disease: 5-year End-of-Study results from the Canadian FACTs trial
err2025-01-10
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errOAAI
errKhan, Aneal; Barber, Dwayne L.; Mckillop, William M.; Rupar, C. Anthony; Auray-Blais, Christiane; Fraser, Graeme; Fowler, Daniel H.; Berger, Alexandra; Foley, Ronan; Keating, Armand; West, Michael L.; Medin, Jeffrey A.
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Cardiac dysfunction and altered gene expression in acid ceramidase-deficient mice
err2025-01-01
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PREAI
errKleynerman, A; Rybova, J; Mckillop, WM; Dlugi, TA; Faber, ML; Fuller, M; O'Meara, CC; Medin, JA
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Hematopoietic stem cell transplantation leads to biochemical and functional correction in two mouse models of acid ceramidase deficiency
err2024-10-01
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errOAAI
errRybova, Jitka; Sundararajan, Teresa; Kuchar, Ladislav; Dlugi, Theresa A.; Ruzicka, Petr; McKillop, William M.; Medin, Jeffrey A.
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Ceramide metabolism alterations contribute to Tumor Necrosis Factor-induced melanoma dedifferentiation and predict resistance to immune checkpoint inhibitors in advanced melanoma patients
err2024-07-29
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errOAAI
errDufau, Carine; Genais, Matthieu; Mucher, Elodie; Jung, Benjamin; Garcia, Virginie; Montfort, Anne; Tosolini, Marie; Clarke, Christopher J.; Medin, Jeffrey A.; Levade, Thierry; Delord, Jean-Pierre; Meyer, Nicolas; Pancaldi, Vera; Andrieu-Abadie, Nathalie; Segui, Bruno
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Novel anti-CD30/CD3 bispecific antibodies activate human T cells and mediate potent anti-tumor activity
err2023-08-14
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errOAAI
errFaber, Mary L.; Oldham, Robyn A. A.; Thakur, Archana; Rademacher, Mary Jo; Kubicka, Ewa; Dlugi, Theresa A.; Gifford, Steven A.; Mckillop, William M.; Schloemer, Nathan J.; Lum, Lawrence G.; Medin, Jeffrey A.
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A mass spectrometry assay for detection of endogenous and lentiviral engineered hemoglobin in cultured cells and sickle cell disease mice
err2023-07-17
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PREAI
errWang, Xuejun; McKillop, William M.; Dlugi, Theresa A.; Faber, Mary L.; Alvarez-Argote, Juliana; Chambers, Christopher B.; Wilber, Andrew; Medin, Jeffrey A.
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Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency
err2023-05-25
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errOAAI
errNagree, Murtaza S.; Rybova, Jitka; Kleynerman, Annie; Ahrenhoerster, Carissa J.; Saville, Jennifer T.; Xu, TianMeng; Bachochin, Maxwell; McKillop, William M.; Lawlor, Michael W.; Pshezhetsky, Alexey V.; Isaeva, Olena; Budde, Matthew D.; Fuller, Maria; Medin, Jeffrey A.
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Pathophysiological characterization of the Townes mouse model for sickle cell disease
err2023-04-01
err7
PREAI
errAlvarez-Argote, Juliana; Dlugi, Theresa A.; Sundararajan, Teresa; Kleynerman, Annie; Faber, Mary L.; McKillop, William M.; Medin, Jeffrey A.
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Autologous, lentivirus-modified, T-rapa cell micropharmacies for lysosomal storage disorders
err2022-03-17
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errOAAI
errNagree, Murtaza S.; Felizardo, Tania C.; Faber, Mary L.; Rybova, Jitka; Rupar, C. Anthony; Foley, S. Ronan; Fuller, Maria; Fowler, Daniel H.; Medin, Jeffrey A.
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Gene therapy for Fabry disease: Progress, challenges, and outlooks on gene-editing
err2021-09-01
err28
PREAI
errDomm, Jakob M.; Wootton, Sarah K.; Medin, Jeffrey A.; West, Michael L.
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Sarcoma IL-12 overexpression facilitates NK cell immunomodulation
err2021-04-15
err13
errOAAI
errRademacher, Mary Jo; Cruz, Anahi; Faber, Mary; Oldham, Robyn A. A.; Wang, Dandan; Medin, Jeffrey A.; Schloemer, Nathan J.
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Lentivirus-mediated gene therapy for Fabry disease
err2021-02-25
err73
errOAAI
errKhan, Aneal; Barber, Dwayne L.; Huang, Ju; Rupar, C. Anthony; Rip, Jack W.; Auray-Blais, Christiane; Boutin, Michel; O'Hoski, Pamela; Gargulak, Kristy; McKillop, William M.; Fraser, Graeme; Wasim, Syed; LeMoine, Kaye; Jelinski, Shelly; Chaudhry, Ahsan; Prokopishyn, Nicole; Morel, Chantal F.; Couban, Stephen; Duggan, Peter R.; Fowler, Daniel H.; Keating, Armand; West, Michael L.; Foley, Ronan; Medin, Jeffrey A.
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Targeting oncoproteins with a positive selection assay for protein degraders
err2021-02-05
err29
errOAAI
errKoduri, Vidyasagar; Duplaquet, Leslie; Lampson, Benjamin L.; Wang, Adam C.; Sabet, Amin H.; Ishoey, Mette; Paulk, Joshiawa; Teng, Mingxing; Harris, Isaac S.; Endress, Jennifer E.; Liu, Xiaoxi; Dasilva, Ethan; Paulo, Joao A.; Briggs, Kimberly J.; Doench, John G.; Ott, Christopher J.; Zhang, Tinghu; Donovan, Katherine A.; Fischer, Eric S.; Gygi, Steven P.; Gray, Nathanael S.; Bradner, James; Medin, Jeffrey A.; Buhrlage, Sara J.; Oser, Matthew G.; Kaelin, William G., Jr.
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Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner
err2020-09-01
err9
PREAI
errBayerle, Aline; Marsching, Christian; Rabionet, Mariona; Dworski, Shaalee; Kamani, Mustafa A.; Chitraju, Chandramohan; Gluchowski, Nina L.; Gabriel, Katlyn R.; Herzer, Silke; Jennemann, Richard; Levade, Thierry; Medin, Jeffrey A.; Sandhoff, Roger
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