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Exploring Long Arm Amide-Linked Side Chains in the Design of Antifungal Azole Inhibitors of Sterol 14α-Demethylase (CYP51) Alsulaimany, Marwa; Keniya, Mikhail V.; Alanazi, Rehab S.; Ruma, Yasmeen N.; Hughes, Carwyn S.; Jones, Arwyn T.; Tyndall, Joel D. A.; Parker, Josie E.; Monk, Brian C.; Simons, Claire Share Save
Exploring medium and long arm extensions of 1,2,4-triazole derivatives as Candida albicans 14α-demethylase (CYP51) inhibitors Alsulaimany, Marwa; Binjubair, Faizah A.; Tatar, Esra; Kelly, Diane E.; Kelly, Steven L.; Warrilow, Andrew G.; Keniya, Mikhail V.; Monk, Brian C.; Parker, Josie E.; Simons, Claire Share Save
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The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species Xie, Jinhong; Rybak, Jeffrey M.; Martin-Vicente, Adela; Guruceaga, Xabier; Thorn, Harrison I.; Nywening, Ashley V.; Ge, Wenbo; Parker, Josie E.; Kelly, Steven L.; Rogers, P. David; Fortwendel, Jarrod R. Share Save
A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1 Rybak, Jeffrey M.; Xie, Jinhong; Martin-Vicente, Adela; Guruceaga, Xabier; Thorn, Harrison I.; Nywening, Ashley V.; Ge, Wenbo; Souza, Ana C. O.; Shetty, Amol C.; McCracken, Carrie; Bruno, Vincent M.; Parker, Josie E.; Kelly, Steven L.; Snell, Hannah M.; Cuomo, Christina A.; Rogers, P. David; Fortwendel, Jarrod R. Share Save
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In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris Rybak, Jeffrey M.; Barker, Katherine S.; Munoz, Jose F.; Parker, Josie E.; Ahmad, Suhail; Mokaddas, Eiman; Abdullah, Aneesa; Elhagracy, Rehab S.; Kelly, Steve L.; Cuomo, Christina A.; Rogers, P. David Share Save
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Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2AΔ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis Ollinger, Tomye L.; Vu, Bao; Murante, Daniel; Parker, Josie E.; Simonicova, Lucia; Doorley, Laura; Stamnes, Mark A.; Kelly, Steven L.; Rogers, P. David; Moye-Rowley, W. Scott; Krysana, Damian J. Share Save
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Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris Rybak, Jeffrey M.; Munoz, Jose F.; Barker, Katherine S.; Parker, Josie E.; Esquivel, Brooke D.; Berkow, Elizabeth L.; Lockhart, Shawn R.; Gade, Lalitha; Palmer, Glen E.; White, Theodore C.; Kelly, Steve L.; Cuomo, Christina A.; Rogers, P. David Share Save
Small-Molecule Inhibitors Targeting Sterol 14α-Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation AgainstCandida albicans Binjubair, Faizah A.; Parker, Josie E.; Warrilow, Andrew G.; Puri, Kalika; Braidley, Peter J.; Tatar, Esra; Kelly, Steven L.; Kelly, Diane E.; Simons, Claire Share Save
Controlled in vitro delivery of voriconazole and diclofenac to the cornea using contact lenses for the treatment of Acanthamoeba keratitis Morgan, Sian R.; Pilia, Nicole; Hewitt, Melissa; Moses, Rachael L.; Moseley, Ryan; Lewis, Philip N.; Morrison, Peter W. J.; Kelly, Steven L.; Parker, Josie E.; Whitaker, David; Quantock, Andrew J.; Heard, Charles M. Share Save
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The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus Furukawa, Takanori; van Rhijn, Norman; Fraczek, Marcin; Gsaller, Fabio; Davies, Emma; Carr, Paul; Gago, Sara; Fortune-Grant, Rachael; Rahman, Sayema; Gilsenan, Jane Mabey; Houlder, Emma; Kowalski, Caitlin H.; Raj, Shriya; Paul, Sanjoy; Cook, Peter; Parker, Josie E.; Kelly, Steve; Cramer, Robert A.; Latge, Jean-Paul; Moye-Rowley, Scott; Bignell, Elaine; Bowyer, Paul; Bromley, Michael J. Share Save
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