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C

Christophe Rochais

universite caen normandie

25H-index
126Paper Count
2.4KCitation Count
Published Papers 63
Publication Date
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Structure-Guided Discovery of a Nonpeptidic MT5-MMP Inhibitor
errACS Medicinal Chemistry Letters
IF4
err2026-05-25
err0
PREAI
errAntoine Magniez; Johanna Giovannini; Pauline Zipfel; Chloé Rémondin; Hassiba Saïdoun; Audrey Davis; Santiago Rivera; Patrick Dallemagne; Christophe Rochais; Alban Lepailleur
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Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer’s Disease
errACS Chemical Neuroscience
IF3.9
err2026-04-13
err0
PREAI
errValentin Travers-Lesage; Marc Since; Alice Wang; Audrey Davis; Dimitri Fayolle; Benoit Bernay; Fabrice Modeste; Florian Nachon; Xavier Brazzalotto; Lucie Crouzier; Jana Sopkova-De Oliveira Santos; Tangui Maurice; Patrick Dallemagne; Christophe Rochais
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Polyfunctionalized N-Arylsulfonyl Indoles: Identification of (E)-N-Hydroxy-3-{3-[(5-(3-(piperidin-1-yl)propoxy]-1H-indol-1-yl)sulfonyl]phenyl}acrylamide (MTP150) for the Epigenetic-based Therapy of Parkinson’s Disease
errInternational Journal of Molecular Sciences
IF4.9
err2026-03-31
err0
errOAAI
errMireia Toledano-Pinedo; Alicia Porro-Pérez; Linda Schäker-Hübner; Daniel Diez-Iriepa; Isabel Iriepa; Agata Siwek; Małgorzata Wolak; Grzegorz Satała; Andrzej J. Bojarski; Agata Doroz-Płonka; Jadwiga Handzlik; Justyna Godyń; Patrick Dallemagne; Christophe Rochais; Audrey Davis; Marc Since; Belén Pérez; Aina Bellver-Sanchis; Alba Irisarri; Mercè Pallàs; Cristina Solana-Manrique; Francisco López-Muñoz; Lhassane Ismaili; Christian Griñán-Ferré; Nuria Paricio; Finn K. Hansen; Anna Więckowska; José Marco-Contelles
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Access to novel potent pleiotropic prodrugs, targeting both butyrylcholinesterase and serotonin reuptake, with anti-amnesic activities in Alzheimer’s disease model.
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-02-12
err0
PREAI
errValentin Travers--Lesage; Lucie Crouzier; Mirjana Antonijevic; Alice Wang; François-Xavier Toublet; Audrey Davis; Fabrice Modeste; Xavier Brazzolotto; Florian Nachon; Marc Since; Tangui Maurice; Christophe Rochais; Patrick Dallemagne
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A combined experimental and computational insights into novel sulfa drug derivatives: Synthesis, DNA binding, molecular docking and DFT studies
errJournal of Molecular Structure
IF4.7
err2025-07-17
err0
PREAI
errUzma Azam; Christophe Rochais; Muhammad Moazzam Naseer
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Targeting together cholinesterases and serotonin reuptake against Alzheimer's disease
errJOURNAL OF PHARMACY AND PHARMACOLOGY
IF3.2
err2025-06-01
err0
PREAI
errGuiselin, Thomas; Lecoutey, Cedric; Rochais, Christophe; Dallemagne, Patrick
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Implication of Central β2 Adrenergic Receptor for the Development of Novel Drugs Against Alzheimer's Disease
errARCHIV DER PHARMAZIE
IF3.6
err2025-04-01
err0
errOAAI
errWang, Alice; Since, Marc; Dallemagne, Patrick; Rochais, Christophe
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Anti-Breast Cancer Properties and In Vivo Safety Profile of a Bis-Carbazole Derivative
errPHARMACEUTICS
IF5.5
err2025-03-25
err0
errOAAI
errCeramella, Jessica; Rosano, Camillo; Iacopetta, Domenico; Ben Toumia, Imene; Chekir-Ghedira, Leila; Maatouk, Mouna; Mariconda, Annaluisa; Longo, Pasquale; Dallemagne, Patrick; Rochais, Christophe; Sinicropi, Maria Stefania
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Analysis of skeletal diversity of multi-target directed ligands (MTDLs) targeting Alzheimer's disease
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-03-01
err0
errOAAI
errAzam, Uzma; Naseer, Muhammad Moazzam; Rochais, Christophe
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Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer's disease by administration through an intranasal route
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-02-01
err0
errOAAI
errGroo, Anne-Claire; Curel, Thomas; Malzert-Freon, Aurelie; Seguy, Line; Bento, Ophelie; Corvaisier, Sophie; Culerier, Thomas; Legrand, Romain; Callizot, Noelle; Henriques, Alexandre; Culley, Georgia; Claeysen, Sylvie; Rochais, Christophe; Dallemagne, Patrick
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Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT4 receptors with potential interest in the treatment of Alzheimer's disease
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-12-01
err0
errOAAI
errRochais, Christophe; Lecoutey, Cedric; Lalut, Julien; Davis, Audrey; Duval, Emilie; Gaven, Florence; Largilliere, Stacy; Nee, Gerald; Corvaisier, Sophie; Santos, Jana Sopkova de Oliveira; Since, Marc; Freret, Thomas; Legrand, Romain; Callizot, Noelle; Claeysen, Sylvie; Boulouard, Michel; Dallemagne, Patrick
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Indirect influence on the BDNF/TrkB receptor signaling pathway via GPCRs, an emerging strategy in the treatment of neurodegenerative disorders
errMEDICINAL RESEARCH REVIEWS
IF11.6
err2024-08-24
err0
errOAAI
errAntonijevic, Mirjana; Dallemagne, Patrick; Rochais, Christophe
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Studies on the mechanisms of action of MR33317
errNAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
IF3.1
err2024-06-10
err1
errOAAI
errNeumann, Joachim; Hesse, C.; Yahiaoui, S.; Dallemagne, P.; Rochais, C.; Hofmann, B.; Gergs, U.
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Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy
errNATURE COMMUNICATIONS
IF15.7
err2024-05-16
err1
errOAAI
errMistretta, Maxime; Cimino, Mena; Campagne, Pascal; Volant, Stevenn; Kornobis, Etienne; Hebert, Olivier; Rochais, Christophe; Dallemagne, Patrick; Lecoutey, Cedric; Tisnerat, Camille; Lepailleur, Alban; Ayotte, Yann; LaPlante, Steven R.; Gangneux, Nicolas; Zahorszka, Monika; Kordulakova, Jana; Vichier-Guerre, Sophie; Bonhomme, Frederic; Pokorny, Laura; Albert, Marvin; Tinevez, Jean-Yves; Manina, Giulia
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Synthesis and interest in medicinal chemistry of β-phenylalanine derivatives (β-PAD): an update (2010-2022)
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2024-05-09
err0
PREAI
errRemondin, Chloe; Mignani, Serge; Rochais, Christophe; Dallemagne, Patrick
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Development of Pleiotropic TrkB and 5-HT4 Receptor Ligands as Neuroprotective Agents
errMOLECULES
IF4.6
err2024-01-19
err4
errOAAI
errAntonijevic, Mirjana; Charou, Despoina; Davis, Audrey; Curel, Thomas; Valcarcel, Maria; Ramos, Isbaal; Villace, Patricia; Claeysen, Sylvie; Dallemagne, Patrick; Gravanis, Achille; Charalampopoulos, Ioannis; Rochais, Christophe
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Conceptual Framework of the Design of Pleiotropic Drugs against Alzheimer's Disease
errPHARMACEUTICS
IF5.5
err2023-09-26
err6
errOAAI
errGuiselin, Thomas; Lecoutey, Cedric; Rochais, Christophe; Dallemagne, Patrick
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Inducing neuronal regeneration and differentiation via the BDNF/TrkB signaling pathway: a key target against neurodegenerative diseases?
errNEURAL REGENERATION RESEARCH
IF6.7
err2023-07-20
err5
errOAAI
errAntonijevic, Mirjana; Dallemagne, Patrick; Rochais, Christophe
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Design, synthesis and biological characterization of novel activators of the TrkB neurotrophin receptor
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-02-01
err5
errOAAI
errAntonijevic, Mirjana; Charou, Despoina; Ramos, Isbaal; Valcarcel, Maria; Gravanis, Achille; Villace, Patricia; Callizot, Noelle; Since, Marc; Dallemagne, Patrick; Charalampopoulos, Ioannis; Rochais, Christophe
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C3-Symmetric Ligands in Drug Design: When the Target Controls the Aesthetics of the Drug
errMOLECULES
IF4.6
err2023-01-10
err7
errOAAI
errAntonijevic, Mirjana; Rochais, Christophe; Dallemagne, Patrick
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Research Directions

No research directions
Co-authors
Cooperation Journals
J
Joël Bockaert
H-index: 101 · Papers: 589
L
Laurent Meijer
H-index: 93 · Papers: 541
J
Joel L. Sussman
H-index: 92 · Papers: 510
B
Brigitte Gicquel
H-index: 87 · Papers: 417
I
Israel Silman
H-index: 82 · Papers: 434
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