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Guo‐Cheng Yuan

icahn school of medicine at mount sinai

80H-index
343Paper Count
2.9WCitation Count
Published Papers 111
Publication Date
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Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer’s disease
errNature Genetics
IF29
err2026-08-11
err0
PREAI
errDonghoon Lee; James M. Vicari; Christian Porras; Collin Spencer; Milos Pjanic; Xinyi Wang; Seon Kinrot; Philipp Weiler; Roman Kosoy; Jaroslav Bendl; Prashant N M; Konstantina Psychogyiou; Periklis Malakates; Evelyn Hennigan; Jennifer Monteiro Fortes; Shiwei Zheng; Karen Therrien; Deepika Mathur; Steven P. Kleopoulos; Zhiping Shao; Stathis Argyriou; Marcela Alvia; Clara Casey; Aram Hong; Kristin G. Beaumont; Robert Sebra; Christopher P. Kellner; David A. Bennett; Guo-Cheng Yuan; Georgios Voloudakis; Fabian J. Theis; Vahram Haroutunian; Gabriel E. Hoffman; John F. Fullard; Panos Roussos
errShare
errSave
SpaDiff denoises sequence-based spatial transcriptomics via diffusion process
errCell Reports Methods
IF4.5
err2026-07-17
err0
errOAAI
errJiazhang Cai; Yongkai Chen; Luyang Fang; Xinyi Liu; Wenxuan Zhong; Guo-Cheng Yuan; Ping Ma
errShare
errSave
The CARM1 epigenetic enzyme inhibits cross-presenting dendritic cell function in cancer immunity
errScience
IF45.8
err2026-07-09
err0
PREAI
errXixi Zhang; Sherin Xirenayi; Ye Zhao; Wen Wang; Yuyang Han; Miguel Sobral; Shawn Kang; Chi Zhang; Graham L. Barlow; Jason Pyrdol; Jae-Won Cho; Kun Huang; Xiaohan Ning; Martin Hemberg; Guo-Cheng Yuan; Eliezer M. Van Allen; David J. Mooney; Kai W. Wucherpfennig
errShare
errSave
sCCIgen: a high-fidelity spatially resolved transcriptomics data simulator for cell–cell interaction studies
errGenome Biology
IF9.4
err2025-10-17
err0
errOAAI
errXiaoyu Song; Joselyn C. Chavez-Fuentes; Weiping Ma; Weijia Fu; Sujung Crystal Shin; Pei Wang; Guo-Cheng Yuan
errShare
errSave
Giotto Suite: a multiscale and technology-agnostic spatial multiomics analysis ecosystem
errNature Methods
IF32.1
err2025-10-01
err0
errOAAI
errJiaji G. Chen; Joselyn C. Chávez-Fuentes; Matthew O’Brien; Junxiang Xu; Edward C. Ruiz; Wen Wang; Iqra Amin; Jeffrey P. Sheridan; Sujung C. Shin; Sanjana V. Hasyagar; Irzam Sarfraz; Pratishtha Guckhool; Adriana Sistig; Veronica Jarzabek; Guo-Cheng Yuan; Ruben Dries
errShare
errSave
ONTraC characterizes spatially continuous variations of tissue microenvironment through niche trajectory analysis
errGENOME BIOLOGY
IF9.4
err2025-05-08
err0
errOAAI
errWang, Wen; Zheng, Shiwei; Shin, Sujung Crystal; Chavez-Fuentes, Joselyn Cristina; Yuan, Guo-Cheng
errShare
errSave
WEST is an ensemble method for spatial transcriptomics analysis
errCELL REPORTS METHODS
IF4.5
err2024-11-01
err0
errOAAI
errCai, Jiazhang; Cheng, Huimin; Wu, Shushan; Zhong, Wenxuan; Yuan, Guo-Cheng; Ma, Ping
errShare
errSave
Systematic analysis identifies a connection between spatial and genomic variations of chromatin states
errCELL SYSTEMS
IF7.7
err2024-11-01
err0
PREAI
errCao, Xuan; Ma, Terry; Fan, Rong; Yuan, Guo-Cheng
errShare
errSave
Spatial transcriptomics defines injury specific microenvironments and cellular interactions in kidney regeneration and disease
errNATURE COMMUNICATIONS
IF15.7
err2024-09-05
err2
errOAAI
errPolonsky, Michal; Gerhardt, Louisa M. S.; Yun, Jina; Koppitch, Kari; Colon, Katsuya Lex; Amrhein, Henry; Wold, Barbara; Zheng, Shiwei; Yuan, Guo-Cheng; Thomson, Matt; Cai, Long; Mcmahon, Andrew P.
errShare
errSave
Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions
errNATURE COMMUNICATIONS
IF15.7
err2024-02-10
err5
errOAAI
errLiu, Tianxin; Zhu, Qian; Kai, Yan; Bingham, Trevor; Wang, Stacy; Cha, Hye Ji; Mehta, Stuti; Schlaeger, Thorsten M.; Yuan, Guo-Cheng; Orkin, Stuart H.
errShare
errSave
Multi-omic profiling of the developing human cerebral cortex at the single-cell level
errSCIENCE ADVANCES
IF12.5
err2023-10-13
err24
errOAAI
errZhu, Kaiyi; Bendl, Jaroslav; Rahman, Samir; Vicari, James M.; Coleman, Claire; Clarence, Tereza; Latouche, Ovaun; Tsankova, Nadejda M.; Li, Aiqun; Brennand, Kristen J.; Lee, Donghoon; Yuan, Guo-Cheng; Fullard, John F.; Roussos, Panos
errShare
errSave
Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC
errBMC GENOMICS
IF3.7
err2023-10-13
err1
errOAAI
errKai, Yan; Liu, Nan; Orkin, Stuart H.; Yuan, Guo-Cheng
errShare
errSave
Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation
errDEVELOPMENTAL CELL
IF8.7
err2023-05-01
err9
errOAAI
errZhou, Pingzhu; Vandusen, Nathan J.; Zhang, Yanchun; Cao, Yangpo; Sethi, Isha; Hu, Rong; Zhang, Shuo; Wang, Guangyu; Ye, Lincai; Mazumdar, Neil; Chen, Jian; Zhang, Xiaoran; Guo, Yuxuan; Li, Bin; Ma, Qing; Lee, Julianna Y.; Gu, Weiliang; Yuan, Guo-Cheng; Ren, Bing; Chen, Kaifu; Pu, William T.
errShare
errSave
Differential Cofactor Requirements for Histone Eviction from Two Nucleosomes at the Yeast PHO84 Promoter Are Determined by Intrinsic Nucleosome Stability
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err35
errOAAI
errWippo, Christian J.; Krstulovic, Bojana Silic; Ertel, Franziska; Musladin, Sanja; Blaschke, Dorothea; Stuerzl, Sabrina; Yuan, Guo-Cheng; Hoerz, Wolfram; Korber, Philipp; Barbaric, Slobodan
errShare
errSave
Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err51
errOAAI
errHu, Tiancen; Yeh, Jennifer E.; Pinello, Luca; Jacob, Jaison; Chakravarthy, Srinivas; Yuan, Guo-Cheng; Chopra, Rajiv; Frank, David A.
errShare
errSave
Differential Roles of Sall4 Isoforms in Embryonic Stem Cell Pluripotency
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err168
errOAAI
errRao, Sridhar; Zhen, Shao; Roumiantsev, Sergei; McDonald, Lindsay T.; Yuan, Guo-Cheng; Orkin, Stuart H.
errShare
errSave
STAT5 Outcompetes STAT3 To Regulate the Expression of the Oncogenic Transcriptional Modulator BCL6
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err82
errOAAI
errWalker, Sarah R.; Nelson, Erik A.; Yeh, Jennifer E.; Pinello, Luca; Yuan, Guo-Cheng; Frank, David A.
errShare
errSave
Construction of a cross-species cell landscape at single-cell level
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-08-05
err45
errOAAI
errWang, Renying; Zhang, Peijing; Wang, Jingjing; Ma, Lifeng; Weigao, E.; Suo, Shengbao; Jiang, Mengmeng; Li, Jiaqi; Chen, Haide; Sun, Huiyu; Fei, Lijiang; Zhou, Ziming; Zhou, Yincong; Chen, Yao; Zhang, Weiqi; Wang, Xinru; Mei, Yuqing; Sun, Zhongyi; Yu, Chengxuan; Shao, Jikai; Fu, Yuting; Xiao, Yanyu; Ye, Fang; Fang, Xing; Wu, Hanyu; Guo, Qile; Fang, Xiunan; Li, Xia; Gao, Xianzhi; Wang, Dan; Xu, Peng-Fei; Zeng, Rui; Xu, Gang; Zhu, Lijun; Wang, Lie; Qu, Jing; Zhang, Dan; Ouyang, Hongwei; Huang, He; Chen, Ming; Ng, Shyh-Chang; Liu, Guang-Hui; Yuan, Guo-Cheng; Guo, Guoji; Han, Xiaoping
errShare
errSave
Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer's disease: review, recommendation, implementation and application
errMOLECULAR NEURODEGENERATION
IF17.5
err2022-03-02
err51
errOAAI
errWang, Minghui; Song, Won-min; Ming, Chen; Wang, Qian; Zhou, Xianxiao; Xu, Peng; Krek, Azra; Yoon, Yonejung; Ho, Lap; Orr, Miranda E.; Yuan, Guo-Cheng; Zhang, Bin
errShare
errSave
MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
errMOLECULAR CELL
IF16.6
err2022-03-01
err35
errOAAI
errOlsen, Sarah Naomi; Godfrey, Laura; Healy, James P.; Choi, Yoolim A.; Kai, Yan; Hatton, Charles; Perner, Florian; Haarer, Elena L.; Nabet, Behnam; Yuan, Guo-Cheng; Armstrong, Scott A.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
S
Stuart H. Orkin
H-index: 179 · Papers: 795
A
Andrew P. McMahon
H-index: 173 · Papers: 477
D
David Mooney
H-index: 172 · Papers: 1.7K
E
Eric P. Winer
H-index: 170 · Papers: 1.6K
R
Roderick T. Bronson
H-index: 164 · Papers: 1.1K
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