Not logged in C071Transcription factor switching drives progression of the classical subtype of pancreatic cancer Rao, Shalini Vasudev; Young, Lisa V.; Cheeseman, Danya; Mack, Stephanie V.; Couturier, Dominique-Laurent; Flynn, Sean V.; Brias, Rebecca; Smith, Amy; Temple, Jill; Jodrell, Duncan; Russell, Alasdair V. Russell; Chernukhin, Igor; Carroll, Jason Share Save
Intratumoral antigen signaling traps CD8+ T cells to confine exhaustion to the tumor site Takahashi, Munetomo; So, Tsz Y.; Chamberlain-Evans, Vitalina; Hughes, Robert; Yam-Puc, Juan Carlos; Kania, Katarzyna; Ruhle, Michelle; Mann, Tiffeney; Schuijs, Martijn J.; Coupland, Paul; Naisbitt, Dean; Halim, Timotheus Y. F.; Lyons, Paul A.; Lio, Pietro; Roychoudhuri, Rahul; Okkenhaug, Klaus; Adams, David J.; Smith, Ken G. C.; Jodrell, Duncan I.; Chapman, Michael A.; Thaventhiran, James E. D. Share Save
Safety and efficacy of AZD8853, an anti-growth and differentiation factor 15 (GDF15) antibody, in patients (pts) with advanced/metastatic solid tumors: First-in-human study Carneiro, Benedito A.; Gbolahan, Olumide; Razak, Albiruni Abdul; Hilton, John F.; Lambert, Arthur; Hood, John; Pluta, Michael; Bragulat, Veronique; Sanai, Elhan; Kumar, Rakesh; Jodrell, Duncan; LoRusso, Patricia Share Save
First-in-human study of AZD8853, an anti-growth and differentiation factor 15 (GDF15) antibody, in patients (pts) with advanced/metastatic solid tumors Carneiro, Benedito A.; Diab, Maria; Van Tine, Brian A.; Shields, Anthony F.; Razak, Albiruni Abdul; Hilton, John F.; Santana-Davila, Rafael; Sanai, Elhan; Zeron-Medina, Jorge; Bragulat, Veronique; Lowery, Kath; Lambert, Arthur; Hood, John; Kumar, Rakesh; Jodrell, Duncan; LoRusso, Patricia Share Save
Clinical and biological markers predictive of treatment response associated with metastatic pancreatic adenocarcinoma Dayimu, Alimu; Di Lisio, Lorena; Anand, Shubha; Roca-Carreras, Isart; Qian, Wendi; Al-Mohammad, Abdulrahman; Basu, Bristi; Valle, Juan W. W.; Jodrell, Duncan; Demiris, Nikos; Corrie, Pippa Share Save
Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging Strittmatter, Nicole; Richards, Frances M.; Race, Alan M.; Ling, Stephanie; Sutton, Daniel; Nilsson, Anna; Wallez, Yann; Barnes, Jennifer; Maglennon, Gareth; Gopinathan, Aarthi; Brais, Rebecca; Wong, Edmond; Serra, Maria Paola; Atkinson, James; Smith, Aaron; Wilson, Joanne; Hamm, Gregory; Johnson, Timothy, I; Dunlop, Charles R.; Kaistha, Brajesh P.; Bunch, Josephine; Sansom, Owen J.; Takats, Zoltan; Andren, Per E.; Lau, Alan; Barry, Simon T.; Goodwin, Richard J. A.; Jodrell, Duncan, I Share Save
Size-tuneable and immunocompatible polymer nanocarriers for drug delivery in pancreatic cancer Popov, Andrea Bistrovic; Melle, Francesca; Linnane, Emily; Gonzalez-Lopez, Cristina; Ahmed, Ishtiaq; Parshad, Badri; Franck, Christoph O.; Rahmoune, Hassan; Richards, Frances M.; Munoz-Espin, Daniel; Jodrell, Duncan, I; Fairen-Jimenez, David; Fruk, Ljiljana Share Save
T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer Li, Dandan; Schaub, Nicholas; Guerin, Theresa M.; Bapiro, Tashinga E.; Richards, Frances M.; Chen, Vicky; Talsania, Keyur; Kumar, Parimal; Gilbert, Debra J.; Schlomer, Jerome J.; Kim, Seong-Jin; Sorber, Rebecca; Teper, Yaroslav; Bautista, Wendy; Palena, Claudia; Ock, Chan-Young; Jodrell, Duncan, I; Pate, Nathan; Mehta, Monika; Zhao, Yongmei; Kozlov, Serguei; Rudloff, Udo Share Save
Quantifying cell cycle-dependent drug sensitivities in cancer using a high throughput synchronisation and screening approach Johnson, Timothy, I; Minteer, Christopher J.; Kottmann, Daniel; Dunlop, Charles R.; Fernandez, Sandra Bernaldo de Quiros; Carnevalli, Larissa S.; Wallez, Yann; Lau, Alan; Richards, Frances M.; Jodrell, Duncan, I Share Save
Mechanisms Underlying Vascular Endothelial Growth Factor Receptor Inhibition-Induced Hypertension The HYPAZ Trial Maki-Petaja, Kaisa M.; McGeoch, Adam; Yang, Lucy L.; Hubsch, Annette; McEniery, Carmel M.; Meyer, Paul A. R.; Mir, Fraz; Gajendragadkar, Parag; Ramenatte, Nicola; Anandappa, Gayathri; Franco, Sara Santos; Bond, Simon J.; Schonlieb, Carola-Bibiane; Boink, Yoeri; Brune, Christoph; Wilkinson, Ian B.; Jodrell, Duncan, I; Cheriyan, Joseph Share Save
CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response Biasci, Daniele; Smoragiewicz, Martin; Connell, Claire M.; Wang, Zhikai; Gao, Ya; Thaventhiran, James E. D.; Basu, Bristi; Magiera, Lukasz; Johnson, T. Isaac; Bax, Lisa; Gopinathan, Aarthi; Isherwood, Christopher; Gallagher, Ferdia A.; Pawula, Maria; Hudecova, Irena; Gale, Davina; Rosenfeld, Nitzan; Barmpounakis, Petros; Popa, Elizabeta Cristina; Brais, Rebecca; Godfrey, Edmund; Mir, Fraz; Richards, Frances M.; Fearo, Douglas T.; Janowitz, Tobias; Jodrell, Duncan I. Share Save
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models Dunlop, Charles R.; Wallez, Yann; Johnson, Timothy Isaac; Fernandez, Sandra Bernaldo de Quiros; Durant, Stephen T.; Cadogan, Elaine B.; Lau, Alan; Richards, Frances M.; Jodrell, Duncan, I Share Save
Opportunities for Quantitative Translational Modeling in Oncology Yates, James W. T.; Byrne, Helen; Chapman, Sonya C.; Chen, Tao; Cucurull-Sanchez, Lourdes; Delgado-SanMartin, Juan; Di Veroli, Giovanni; Dovedi, Simon J.; Dunlop, Carina; Jena, Rajesh; Jodrell, Duncan; Martin, Emma; Mercier, Francois; Ramos-Montoya, Antonio; Struemper, Herbert; Vicini, Paolo Share Save
Scheduling nab-paclitaxel combined with gemcitabine as first-line treatment for metastatic pancreatic adenocarcinoma Corrie, P. G.; Qian, W.; Basu, B.; Valle, J. W.; Falk, S.; Iwuji, C.; Wasan, H.; Palmer, D.; Scott-Brown, M.; Wadsley, J.; Arif, S.; Bridgewater, J.; Propper, D.; Gillmore, R.; Gopinathan, A.; Skells, R.; Bundi, P.; Brais, R.; Dalchau, K.; Bax, L.; Chhabra, A.; Machin, A.; Dayim, A.; McAdam, K.; Cummins, S.; Wall, L.; Ellis, R.; Anthoney, A.; Evans, J.; Ma, Y. T.; Isherwood, C.; Neesse, A.; Tuveson, D.; Jodrell, D., I Share Save
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Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors Sale, Matthew J.; Minihane, Emma; Monks, Noel R.; Gilley, Rebecca; Richards, Frances M.; Schifferli, Kevin P.; Andersen, Courtney L.; Davies, Emma J.; Vicente, Mario Aladren; Ozono, Eiko; Markovets, Aleksandra; Dry, Jonathan R.; Drew, Lisa; Flemington, Vikki; Proia, Theresa; Jodrell, Duncan I.; Smith, Paul D.; Cook, Simon J. Share Save
A Highly Porous Metal-Organic Framework System to Deliver Payloads for Gene Knockdown Teplensky, Michelle H.; Fantham, Marcus; Poudel, Chetan; Hockings, Colin; Lu, Meng; Guna, Alina; Aragones-Anglada, Marta; Moghadam, Peyman Z.; Li, Peng; Farha, Omar K.; Fernandez, Sandra Bernaldo de Quiros; Richards, Frances M.; Jodrell, Duncan, I; Schierle, Gabriele Kaminski; Kaminski, Clemens F.; Fairen-Jimenez, David Share Save
Quantifying Drug-Induced Bone Marrow Toxicity Using a Novel Haematopoiesis Systems Pharmacology Model Fornari, Chiara; O'Connor, Lenka Oplustil; Pin, Carmen; Smith, Aaron; Yates, James W. T.; Cheung, S. Y. Amy; Jodrell, Duncan, I; Mettetal, Jerome T.; Collins, Teresa A. Share Save
SPARC dependent collagen deposition and gemcitabine delivery in a genetically engineered mouse model of pancreas cancer Ramu, Iswarya; Buchholz, Soeren M.; Patzak, Melanie S.; Goetze, Robert G.; Singh, Shiv K.; Richards, Frances M.; Jodrell, Duncan, I; Sipos, Bence; Stroebel, Philipp; Ellenrieder, Volker; Hessmann, Elisabeth; Neesse, Albrecht Share Save
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