Not logged inINA03: A Potent Transferrin-Competitive Antibody-Drug Conjugate against CD71 for Safer Acute Leukemia Treatment
Bratti, Manuela; Stubbs, Elisa; Kolodych, Sergii; Souchet, Herve; Kelly, Lois; Merlin, Johanna; Marchal, Michelle; Castellano, Remy; Josselin, Emmanuelle; Pasquer, Helene; Benajiba, Lina; Puissant, Alexandre; Koniev, Oleksandr; Collette, Yves; Belanger, Coralie; Hermine, Olivier; Monteiro, Renato C.; Launay, Pierre
Share
Saveα-Ag2S nanoparticles: low-temperature syntheses, crystallisation pathway, and first operando luminescence measurements for sodium-ion battery applications
Stroeh, J.; Ohrt, L.; Harder, A.; Collette, Y.; Liers, L.; Teotonio, E.; Novikov, D.; Khadiev, A.; Teske, C. L.; Terraschke, H.
Share
SavePreclinical characterization of ETx-22, a next-generation antibody drug conjugate (ADC) targeting nectin-4
Azim, Hatem; Lhospice, Florence; Preville, Xavier; Fares, Joanna; Lopez, Marc; Crompot, Emerence; Josselin, Emmanuelle; Castellano, Remy; Wehbeh, Maria; Collette, Yves; Elands, Jack; Olive, Daniel
Share
SaveDownregulation of stromal syntenin sustains AML development
Leblanc, Raphael; Ghossoub, Rania; Goubard, Armelle; Castellano, Remy; Fares, Joanna; Camoin, Luc; Audebert, Stephane; Balzano, Marielle; Bou-Tayeh, Berna; Fauriat, Cyril; Vey, Norbert; Garciaz, Sylvain; Borg, Jean-Paul; Collette, Yves; Aurrand-Lions, Michel; David, Guido; Zimmermann, Pascale
Share
SaveCD36 Drives Metastasis and Relapse in Acute Myeloid Leukemia
Farge, Thomas; Nakhle, Jean; Lagarde, Damien; Cognet, Guillaume; Polley, Nathaniel; Castellano, Remy; Nicolau, Marie-Laure; Bosc, Claudie; Sabatier, Marie; Sahal, Ambrine; Saland, Estelle; Jeanson, Yannick; Guiraud, Nathan; Boet, Emeline; Bergoglio, Camille; Gotanegre, Mathilde; Mouchel, Pierre-Luc; Stuani, Lucille; Larrue, Clement; Sallese, Marie; De Mas, Veronique; Moro, Cedric; Dray, Cedric; Collette, Yves; Raymond-Letron, Isabelle; Ader, Isabelle; Recher, Christian; Sarry, Jean-Emmanuel; Cabon, Florence; Vergez, Francois; Carriere, Audrey
Share
SaveFrom a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia
Saez-Ayala, Magali; Hoffer, Laurent; Abel, Sebastien; Ben Yaala, Khaoula; Sicard, Benoit; Andrieu, Guillaume P.; Latiri, Mehdi; Davison, Emma K.; Ciufolini, Marco A.; Bremond, Paul; Rebuffet, Etienne; Roche, Philippe; Derviaux, Carine; Voisset, Edwige; Montersino, Camille; Castellano, Remy; Collette, Yves; Asnafi, Vahid; Betzi, Stephane; Dubreuil, Patrice; Combes, Sebastien; Morelli, Xavier
Share
SaveC/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress-Induced Ferroptosis in FLT3-Mutant Leukemia
Sabatier, Marie; Birsen, Rudy; Lauture, Laura; Mouche, Sarah; Angelino, Paolo; Dehairs, Jonas; Goupille, Lea; Boussaid, Ismael; Heiblig, Mael; Boet, Emeline; Sahal, Ambrine; Saland, Estelle; Santos, Juliana C.; Armengol, Marc; Fernandez-Serrano, Miranda; Farge, Thomas; Cognet, Guillaume; Simonetta, Federico; Pignon, Corentin; Graffeuil, Antoine; Mazzotti, Celine; Avet-Loiseau, Herve; Delos, Oceane; Bertrand-Michel, Justine; Chedru, Amelie; Dembitz, Vilma; Gallipoli, Paolo; Anstee, Natasha S.; Loo, Sun; Wei, Andrew H.; Carroll, Martin; Goubard, Armelle; Castellano, Remy; Collette, Yves; Vergez, Francois; Mansat-De Mas, Veronique; Bertoli, Sarah; Tavitian, Suzanne; Picard, Muriel; Recher, Christian; Bourges-Abella, Nathalie; Granat, Fanny; Kosmider, Olivier; Sujobert, Pierre; Colsch, Benoit; Joffre, Carine; Stuani, Lucille; Swinnen, Johannes V.; Guillou, Herve; Roue, Gael; Hakim, Nawad; Dejean, Anne S.; Tsantoulis, Petros; Larrue, Clement; Bouscary, Didier; Tamburini, Jerome; Sarry, Jean-Emmanuel
Share
SavePotentiation of tumor necrosis factor-induced NF-κB activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of IκBα
Adam, E; Quivy, V; Bex, F; Chariot, A; Collette, Y; Vanhulle, C; Schoonbroodt, S; Goffin, V; Nguyên, TLA; Gloire, G; Carrard, G; Friguet, B; de Launoit, Y; Burny, A; Bours, V; Piette, J; Van Lint, CV
Share
SavePotentiation of tumor necrosis factor-induced NF-κB activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of IκBα (vol 23, pg 6200, 2003)
Adam, E; Quivy, V; Bex, F; Chariot, A; Collette, Y; Vanhulle, C; Schoonbroodt, S; Goffin, W; Nguyen, TLA; Gloire, G; Carrard, G; Friguet, B; de Launoit, Y; Burny, A; Bours, V; Piette, J; Van Lint, C
Share
SaveAlternative Splicing Modulates Autoinhibition and SH3 Accessibility in the Src Kinase Fyn
Brignatz, C.; Paronetto, M. P.; Opi, S.; Cappellari, M.; Audebert, S.; Feuillet, V.; Bismuth, G.; Roche, S.; Arold, S. T.; Sette, C.; Collette, Y.
Share
Save
Share
SaveRAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia
Decroocq, Justine; Birsen, Rudy; Montersino, Camille; Chaskar, Prasad; Mano, Jordi; Poulain, Laury; Friedrich, Chloe; Alary, Anne-Sophie; Guermouche, Helene; Sahal, Ambrine; Fouquet, Guillemette; Gotanegre, Mathilde; Simonetta, Federico; Mouche, Sarah; Gestraud, Pierre; Lescure, Auriane; Del Nery, Elaine; Bosc, Claudie; Grenier, Adrien; Mazed, Fetta; Mondesir, Johanna; Chapuis, Nicolas; Ho, Liza; Boughalem, Aicha; Lelorc'h, Marc; Gobeaux, Camille; Fontenay, Michaela; Recher, Christian; Vey, Norbert; Guille, Arnaud; Birnbaum, Daniel; Hermine, Olivier; Radford-Weiss, Isabelle; Tsantoulis, Petros; Collette, Yves; Castellano, Remy; Sarry, Jean-Emmanuel; Pasmant, Eric; Bouscary, Didier; Kosmider, Olivier; Tamburini, Jerome
Share
SaveCRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation
Carrasco, Kendall; Montersino, Camille; Derviaux, Carine; Saez-Ayala, Magali; Hoffer, Laurent; Restouin, Audrey; Castellano, Remy; Casassa, Justine; Roche, Philippe; Pasquier, Eddy; Combes, Sebastien; Morelli, Xavier; Collette, Yves; Betzi, Stephane
Share
SaveDevelopment of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell-mediated antitumor immune response
De Gassart, Aude; Le, Kieu-Suong; Brune, Patrick; Agaugue, Sophie; Sims, Jennifer; Goubard, Armelle; Castellano, Remy; Joalland, Noemie; Scotet, Emmanuel; Collette, Yves; Valentin, Emmanuel; Ghigo, Clement; Pasero, Christine; Colazet, Magali; Guillen, Jaime; Cano, Carla E.; Marabelle, Aurelien; De Bonno, Johann; Hoet, Rene; Truneh, Alemseged; Olive, Daniel; Frohna, Paul
Share
SaveSynergy and allostery in ligand binding by HIV-1 Nef
Aldehaiman, Abdullah; Momin, Afaque A.; Restouin, Audrey; Wang, Luyao; Shi, Xiaoli; Aljedani, Safia; Opi, Sandrine; Lugari, Adrien; Hameed, Umar F. Shahul; Ponchon, Luc; Morelli, Xavier; Huang, Mingdong; Dumas, Christian; Collette, Yves; Arold, Stefan T.
Share
SaveMitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
Stuani, Lucille; Sabatier, Marie; Saland, Estelle; Cognet, Guillaume; Poupin, Nathalie; Bosc, Claudie; Castelli, Florence A.; Gales, Lara; Turtoi, Evgenia; Montersino, Camille; Farge, Thomas; Boet, Emeline; Broin, Nicolas; Larrue, Clement; Baran, Natalia; Cisse, Madi Y.; Conti, Marc; Loric, Sylvain; Kaoma, Tony; Hucteau, Alexis; Zavoriti, Aliki; Sahal, Ambrine; Mouchel, Pierre-Luc; Gotanegre, Mathilde; Cassan, Cedric; Fernando, Laurent; Wang, Feng; Hosseini, Mohsen; Chu-Van, Emeline; Le Cam, Laurent; Carroll, Martin; Selak, Mary A.; Vey, Norbert; Castellano, Remy; Fenaille, Francois; Turtoi, Andrei; Cazals, Guillaume; Bories, Pierre; Gibon, Yves; Nicolay, Brandon; Ronseaux, Sebastien; Marszalek, Joseph R.; Takahashi, Koichi; DiNardo, Courtney D.; Konopleva, Marina; Pancaldi, Vera; Collette, Yves; Bellvert, Floriant; Jourdan, Fabien; Linares, Laetitia K.; Recher, Christian; Portais, Jean-Charles; Sarry, Jean-Emmanuel
Share
SaveICOS is widely expressed in cutaneous T-cell lymphoma, and its targeting promotes potent killing of malignant cells
Amatore, Florent; Ortonne, Nicolas; Lopez, Marc; Orlanducci, Florence; Castellano, Remy; Ingen-Housz-Oro, Saskia; De Croos, Amandine; Salvado, Clementine; Gorvel, Laurent; Goubard, Arrnelle; Collette, Yves; Bouabdallah, Reda; Schiano, Jean-Marc; Bonnet, Nathalie; Grob, Jean-Jacques; Gaulard, Philippe; Bagot, Martine; Bensussan, Armand; Berbis, Philippe; Olive, Daniel
Share
SaveIn silicomolecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
Ariey-Bonnet, Jeremy; Carrasco, Kendall; Le Grand, Marion; Hoffer, Laurent; Betzi, Stephane; Feracci, Mikael; Tsvetkov, Philipp; Devred, Francois; Collette, Yves; Morelli, Xavier; Ballester, Pedro; Pasquier, Eddy
Share
SaveCD95L Cell Surface Cleavage Triggers a Prometastatic Signaling Pathway in Triple-Negative Breast Cancer (vol 73, pg 6711, 2013)
Malleter, Marine; Tauzin, Sebastien; Bessede, Alban; Castellano, Remy; Goubard, Armelle; Godey, Florence; Leveque, Jean; Jezequel, Pascal; Campion, Loic; Campone, Mario; Ducret, Thomas; MacGrogan, Gaetan; Debure, Laure; Collette, Yves; Vacher, Pierre; Legembre, Patrick
Share
SaveA gain-of-function RAC2 mutation is associated with bone marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency
Lagresle-Peyrou, Chantal; Olichon, Aurelien; Sadek, Hanem; Roche, Philippe; Tardy, Claudine; Da Silva, Cindy; Garrigue, Alexandrine; Fischer, Alain; Moshous, Despina; Collette, Yves; Picard, Capucine; Casanova, Jean Laurent; Andre, Isabelle; Cavazzana, Marina
Share
Save