Not logged in Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement Velcicky, Juraj; Langlois, Jean-Baptiste; Wright, Michael; Janser, Philipp; Angst, Daniela; Arnold, Christelle; Beltz, Karen; Brenneisen, Silke; Dubois, Celine; Dawson, Janet; Fischer, Christian; Gommermann, Nina; Heizmann, Andreas; Ilic, Slavica; Machauer, Rainer; Maschlej, Magdalena; Monnerat, Sarah; Pflieger, Daniel; Ristov, Jacinda; Rubert, Joelle; Schwalm, Gunther; Smith, Daniel R.; Srinivas, Honnappa; Steiner, Roland; Stojanovic, Aleksandar; Troxler, Thomas; Unterreiner, Adeline; Vangrevelinghe, Eric; von Burg, Nicole; Wunderlich, Jennifer; Farady, Christopher J.; Mackay, Angela Share Save
[18F]NP3-627, a Candidate PET Imaging Agent Targeting the NLRP3 Inflammasome in the Central Nervous System Whitehead, David M.; Fischer, Christian; Briard, Emmanuelle; Farady, Christopher J.; Graveleau, Nadege; Karrer, Joel; Kaupmann, Klemens; Lapointe, Guillaume; Mackay, Angela; Reichert, Lisa; Wright, Michael; Mu, Linjing; Auberson, Yves P. Share Save
Discovery of NP3-253, a Potent Brain Penetrant Inhibitor of the NLRP3 Inflammasome Mackay, Angela; Velcicky, Juraj; Gommermann, Nina; Mattes, Henri; Janser, Philipp; Wright, Michael; Dubois, Celine; Brenneisen, Silke; Ilic, Slavica; Vangrevelinghe, Eric; Stiefl, Nikolaus; Boettcher, Andreas; Schoenboerner, Michel; Vogelsanger, Melanie; Muller-Bentz, Sophie; Kamke, Marion; Rubert, Joelle; Kauffmann, Muriel; Desrayaud, Sandrine; Trunzer, Markus; Srinivas, Honnappa; Hinniger, Alexandra; von Burg, Nicole; Beltz, Karen; Dekker, Carien; Farady, Christopher J. Share Save
The Lancet Commission on self-harm Moran, Paul; Chandler, Amy; Dudgeon, Pat; Kirtley, Olivia J.; Knipe, Duleeka; Pirkis, Jane; Sinyor, Mark; Allister, Rosie; Ansloos, Jeffrey; Ball, Melanie A.; Chan, Lai Fong; Darwin, Leilani; Derry, Kate L.; Hawton, Keith; Heney, Veronica; Hetrick, Sarah; Li, Ang; Machado, Daiane B.; Mcallister, Emma; Mcdaid, David; Mehra, Ishita; Niederkrotenthaler, Thomas; Nock, Matthew K.; O'Keefe, Victoria M.; Oquendo, Maria A.; Osafo, Joseph; Patel, Vikram; Pathare, Soumitra; Peltier, Shanna; Roberts, Tessa; Robinson, Jo; Shand, Fiona; Stirling, Fiona; Stoor, Jon P. A.; Swingler, Natasha; Turecki, Gustavo; Venkatesh, Svetha; Waitoki, Waikaremoana; Wright, Michael; Yip, Paul S. F.; Spoelma, Michael J.; Kapur, Navneet; O'Connor, Rory C.; Christensen, Helen Share Save
Discovery of ginisortamab, a potent and novel anti-gremlin-1 antibody in clinical development for the treatment of cancer Davies, Gareth C. G.; Dedi, Neesha; Jones, Paul S.; Kevorkian, Lara; McMillan, David; Ottone, Cristina; Schulze, Monika-Sarah E. D.; Scott-Tucker, Anthony; Tewari, Roohi; West, Shauna; Wright, Michael; Rowley, Tania F. Share Save
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Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling Goldstein, Nathaniel B.; Steel, Andrea; Barbulescu, Chauncey C.; Koster, Maranke, I; Wright, Michael J.; Jones, Kenneth L.; Gao, Bifeng; Ward, Brian; Woessner, Brian; Trottier, Zachary; Pakieser, Jen; Hu, Junxiao; Lambert, Karoline A.; Shellman, Yiqun G.; Fujita, Mayumi; Robinson, William A.; Roop, Dennis R.; Norris, David A.; Birlea, Stanca A. Share Save
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Structurally Mapping Antibody Repertoires Krawczyk, Konrad; Kelm, Sebastian; Kovaltsuk, Aleksandr; Galson, Jacob D.; Kelly, Dominic; Trueck, Johannes; Regep, Cristian; Leem, Jinwoo; Wong, Wing K.; Nowak, Jaroslaw; Snowden, James; Wright, Michael; Starkie, Laura; Scott-Tucker, Anthony; Shi, Jiye; Deane, Charlotte M. Share Save
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Activation Of RHOJ signaling in human hair follicle bulge melanocytes is a key-factor In NBUVB induction of vitiligo repigmentation Goldstein, N.; Pakieser, J.; Wright, M.; Caldwell, C.; Krug, A.; Koster, M.; Jones, K.; Gao, B.; Ward, B.; Venkataraman, S.; Lambert, K.; Shellman, Y.; Fujita, M.; Roop, D. R.; Norris, D.; Birlea, S. Share Save
Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the β-Catenin Pathway in the Hair Follicle Bulge Stem Cells Goldstein, Nathaniel B.; Koster, Maranke I.; Jones, Kenneth L.; Gao, Bifeng; Hoaglin, Laura G.; Robinson, Steven E.; Wright, Michael J.; Birlea, Smaranda I.; Luman, Abigail; Lambert, Karoline A.; Shellman, Yiqun G.; Fujita, Mayumi; Robinson, William A.; Roop, Dennis R.; Norris, David A.; Birlea, Stanca A. Share Save
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Design and Synthesis of Novel, Selective GPR40 AgoPAMs Plummer, Christopher W.; Clements, Matthew J.; Chen, Helen; Rajagopalan, Murali; Josien, Hubert; Hagmann, William K.; Miller, Michael; Trujillo, Maria E.; Kirkland, Melissa; Kosinski, Daniel; Mane, Joel; Pachanski, Michele; Cheewatrakoolpong, Boonlert; Nolting, Andrew F.; Orr, Robert; Christensen, Melodie; Campeau, Louis-Charles; Wright, Michael J.; Bugianesi, Randal; Souza, Sarah; Zhang, Xiaoping; Di Salvo, Jerry; Weinglass, Adam B.; Tschirret-Guth, Richard; Nargund, Ravi; Howard, Andrew D.; Colletti, Steven L. Share Save
Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein: protein interaction and modulates its downstream signaling Adams, Ralph; Burnley, Rebecca J.; Valenzano, Chiara R.; Qureshi, Omar; Doyle, Carl; Lumb, Simon; Lopez, Maria del Carmen; Griffin, Robert; McMillan, David; Taylor, Richard D.; Meier, Chris; Mori, Prashant; Griffin, Laura M.; Wernery, Ulrich; Kinne, Joerg; Rapecki, Stephen; Baker, Terry S.; Lawson, Alastair D. G.; Wright, Michael; Ettorre, Anna Share Save
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