Not logged in Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit Senatorov, Ilya S.; Bowman, Joel; Jansson, Keith H.; Alilin, Aian Neil; Capaldo, Brian J.; Lake, Ross; Riba, Morgan; Abbey, Yasmine C.; Mcknight, Crystal; Zhang, Xiaohu; Raj, Sonam; Beshiri, Michael L.; Shinn, Paul; Nguyen, Holly; Thomas, Craig J.; Corey, Eva; Kelly, Kathleen Share Save
Stem cell dynamics and cellular heterogeneity across lineage subtypes of castrate-resistant prostate cancer Beshiri, Michael L.; Capaldo, Brian J.; Lake, Ross; Ku, Anson T.; Burner, Danielle; Tice, Caitlin M.; Tran, Crystal; Kostas, Julianna; Alilin, Aian Neil; Yin, Juanjuan; Agarwal, Supreet; Morris, Samantha A.; Karzai, Fatima H.; Lotan, Tamara L.; Dahut, William L.; Sowalsky, Adam G.; Kelly, Kathleen Share Save
Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models Agarwal, Supreet; Fang, Lei; Mcgowen, Kerry; Yin, Juanjuan; Bowman, Joel; Ku, Anson T.; Alilin, Aian Neil; Corey, Eva; Roudier, Martine P.; True, Lawrence D.; Dumpit, Ruth; Coleman, Ilsa; Lee, John K.; Nelson, Peter S.; Capaldo, Brian J.; Mariani, Aida; Hoover, Clare; Senatorov, Ilya S.; Beshiri, Michael; Sowalsky, Adam G.; Hurt, Elaine M.; Kelly, Kathleen Share Save
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Targeting the PI3K/AKT Pathway Overcomes Enzalutamide Resistance by Inhibiting Induction of the Glucocorticoid Receptor Adelaiye-Ogala, Remi; Gryder, Berkley E.; Yen Thi Minh Nguyen; Alilin, Aian Neil; Grayson, Adlai R.; Bajwa, Wardah; Jansson, Keith H.; Beshiri, Michael L.; Agarwal, Supreet; Rodriguez-Nieves, Jose Antonio; Capaldo, Brian; Kelly, Kathleen; VanderWeele, David J. Share Save
CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer Hwang, Justin H.; Seo, Ji-Heui; Beshiri, Michael L.; Wankowicz, Stephanie; Liu, David; Cheung, Alexander; Li, Ji; Qiu, Xintao; Hong, Andrew L.; Botta, Ginevra; Golumb, Lior; Richter, Camden; So, Jonathan; Sandoval, Gabriel J.; Giacomelli, Andrew O.; Ly, Seav Huong; Han, Celine; Dai, Chao; Pakula, Hubert; Sheahan, Anjali; Piccioni, Federica; Gjoerup, Ole; Loda, Massimo; Sowalsky, Adam G.; Ellis, Leigh; Long, Henry; Root, David E.; Kelly, Kathleen; Van Allen, Eliezer M.; Freedman, Matthew L.; Choudhury, Atish D.; Hahn, William C. Share Save
The Indenoisoquinoline TOP1 Inhibitors Selectively Target Homologous Recombination-Deficient and Schlafen 11-Positive Cancer Cells and Synergize with Olaparib Marzi, Laetitia; Szabova, Ludmila; Gordon, Melanie; Ohler, Zoe Weaver; Sharan, Shyam K.; Beshiri, Michael L.; Etemadi, Moudjib; Murai, Junko; Kelly, Kathleen; Pommier, Yves Share Save
EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis Li, Lechen; Ameri, Amir H.; Wang, Simeng; Jansson, Keith H.; Casey, Orla M.; Yang, Qi; Beshiri, Michael L.; Fang, Lei; Lake, Ross G.; Agarwal, Supreet; Alilin, Aian N.; Xu, Wanhai; Yin, JuanJuan; Kelly, Kathleen Share Save
Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations Karzai, Fatima; VanderWeele, David; Madan, Ravi A.; Owens, Helen; Cordes, Lisa M.; Hankin, Amy; Couvillon, Anna; Nichols, Erin; Bilusic, Marijo; Beshiri, Michael L.; Kelly, Kathleen; Krishnasamy, Venkatesh; Lee, Sunmin; Lee, Min-Jung; Yuno, Akira; Trepel, Jane B.; Merino, Maria J.; Dittamore, Ryan; Marte, Jennifer; Donahue, Renee N.; Schlom, Jeffrey; Killian, Keith J.; Meltzer, Paul S.; Steinberg, Seth M.; Gulley, James L.; Lee, Jung-Min; Dahut, William L. Share Save
High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer Jansson, Keith H.; Tucker, John B.; Stahl, Lauren E.; Simmons, John K.; Fuller, Caitlyn; Beshiri, Michael L.; Agarwal, Supreet; Fang, Lei; Hynes, Paul G.; Alilin, Aian Neil; Lake, Ross; Abbey, Yasmine C.; Cawley, Jacob; Tice, Caitlin M.; Yin, JuanJuan; McKnight, Crystal; Klummp-Thomas, Carleen; Zhang, Xiaohu; Guha, Rajarshi; Hoover, Shelley; Simpson, R. Mark; Nguyen, Holly M.; Corey, Eva; Thomas, Craig J.; Proia, David A.; Kelly, Kathleen Share Save
A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening Beshiri, Michael L.; Tice, Caitlin M.; Tran, Crystal; Nguyen, Holly M.; Sowalsky, Adam G.; Agarwal, Supreet; Jansson, Keith H.; Yang, Qi; McGowen, Kerry M.; Yin, JuanJuan; Alilin, Aian Neil; Karzai, Fatima H.; Dahut, William L.; Corey, Eva; Kelly, Kathleen Share Save
PDX-derived and patient-derived prostate cancer organoids as a clinically relevant platform for translational research. Beshiri, Michael L.; Tice, Caitlin M.; Tran, Crystal; Nguyen, Holly M.; Sowalsky, Adam G.; Agarwal, Supreet; Jansson, Keith H.; McGowen, Kerry; Alilin, Aian Neil; Yin, JuanJuan; Karzai, Fatima H.; Dahut, William L.; Corey, Eva; Kelly, Kathleen Share Save
A high-throughput screen identifies HSP90 inhibitors as potent therapeutics across multiple clinically representative organoid models of advanced prostate cancer Jansson, Keith H.; Tucker, John B.; Stahl, Lauren E.; Simmons, John K.; Fuller, Caitlyn; Beshiri, Michael L.; Agarwal, Supreet; Abbey, Yasmine; Fang, Lei; Hynes, Paul G.; Neil, Alilin Aian; Cawley, Jacob; Lake, Ross; Tran, Crystal; Tice, Caitlin M.; Yin, JuanJuan; Zhang, Xiahu; Guha, Rajarshi; Hoover, Shelley; Simpson, R. Mark; Nguyen, Holly; Corey, Eva; Thomas, Craig J.; Proia, David; Kelly, Kathleen Share Save
High-throughput screen identifies HSP90 as a potential therapeutic target in models of advanced CRPC Jansson, Keith H.; Tucker, John; Stahl, Lauren; Fuller, Caitlyn; Beshiri, Michael; Simmons, John K.; Agarwal, Supreet; Fang, Lei; Alilin, Aian Neil; Lake, Ross; Tran, Crystal; Hynes, Paul G.; Cawley, Jacob; Yin, JuanJuan; Zhang, Xiaohu; Guha, Rajarshi; Hoover, Shelley; Simpson, R. Mark; Nguyen, Holly; Corey, Eva; Thomas, Craig; Proia, David; Kelly, Kathleen Share Save
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation Beshiri, Michael L.; Holmes, Katherine B.; Richter, William F.; Hess, Samuel; Islam, Abul B. M. M. K.; Yan, Qin; Plante, Lydia; Litovchick, Larisa; Gevry, Nicolas; Lopez-Bigas, Nuria; Kaelin, William G., Jr.; Benevolenskaya, Elizaveta V. Share Save
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 Lin, Wenchu; Cao, Jian; Liu, Jiayun; Beshiri, Michael L.; Fujiwara, Yuko; Francis, Joshua; Cherniack, Andrew D.; Geisen, Christoph; Blair, Lauren P.; Zou, Mike R.; Shen, Xiaohua; Kawamori, Dan; Liu, Zongzhi; Grisanzio, Chiara; Watanabe, Hideo; Minamishima, Yoji Andrew; Zhang, Qing; Kulkarni, Rohit N.; Signoretti, Sabina; Rodig, Scott J.; Bronson, Roderick T.; Orkin, Stuart H.; Tuck, David P.; Benevolenskaya, Elizaveta V.; Meyerson, Matthew; Kaelin, William G., Jr.; Yan, Qin Share Save
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