Suresh V. Ambudkar - Publications, H-index & Citations

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Suresh V. Ambudkar

NIH

87H-index

475Paper Count

2.9WCitation Count

Published Papers 197

Publication Date

Attenuation of ABCG2-dependent drug efflux by befotertinib restores chemosensitivity in multidrug-resistant non-small cell lung cancer cells

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2026-06-09

OAAI

Yen-Ching Li; Ting-Yu Chen; Hui-Chiau Chuang; Bing-Huan Lin; Megumi Murakami; Yu-Tzu Chang; Yu-Shan Wu; Tai-Ho Hung; Suresh.V. Ambudkar; Chung-Pu Wu

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Functional implications of the conformational landscape of a multidrug transporter revealed by Zebrafish Abcb4 structures

Nature Communications

IF15.7

2026-05-30

OAAI

Jingyu Zhan; Chao-Ming Hsieh; Lothar Esser; Zabrina C. Lang; Abraham J. Morton; Robert Robey; Fei Zhou; Suresh V. Ambudkar; Rick K. Huang; Michael M. Gottesman; Di Xia

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Lirafugratinib attenuates ABCG2-dependent drug efflux and restores chemosensitivity in multidrug-resistant nonsmall cell lung cancer cells

Drug Metabolism and Disposition

IF4

2026-04-01

PREAI

Wu, Chung-Pu; Li, Yen-Ching; Lin, Bing-Huan; Murakami, Megumi; Chang, Yu-Tzu; Wu, Yu-Shan; Hung, Tai-Ho; Ambudkar, Suresh. V.

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Self-assembled verteporfin nanoparticles decrease drug efflux by P-glycoprotein without light activation in drug-resistant cancer cells

Bioengineering & Translational Medicine

IF5.7

2026-03-20

OAAI

Idrisa Rahman; Anju Meda; Kaitlyn A. Moore; Andaleeb Sajid; Suresh V. Ambudkar; Huang Chiao Huang

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(N)-Methanocarba Adenosine Derivatives as Dual Modulators of P-Glycoprotein and ABCG2 Transporters

Journal of Medicinal Chemistry

IF6.8

2026-02-01

PREAI

Murakami, Megumi; Tosh, Dilip K.; Salazar, Paula B.; Jacobson, Kenneth A.; Ambudkar, Suresh V.

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Tetrahydroquinoline/4,5-dihydroisoxazoline derivatives counteract multidrug resistance in cancer cells by inhibiting P-glycoprotein (ABCB1)-mediated transport

Biochimica et Biophysica Acta (BBA) - General Subjects

IF0

2025-12-04

PREAI

Marina Hembecker; Diogo Henrique Kita; Azam Rashidian; Luis C. Vesga; Bruna Estelita Ruginsk; Arnold R. Romero Bohórquez; Stelia Carolina Mendez-Sanchez; Vinicius Goncalves Maltarollo; Fabiane Gomes de Moraes Rego; Geraldo Picheth; Antti Poso; Katalin Goda; Suresh V. Ambudkar; Vivian Rotuno Moure; Thales Kronenberger; Glaucio Valdameri

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Erratum to “The fourth-generation EGFR tyrosine kinase inhibitor BLU-945 resensitizes ABCG2-overexpressing multidrug-resistant non-small cell lung cancer cells to cytotoxic anticancer drugs” [European Journal of Pharmaceutical Sciences (2025) 107337]

European Journal of Pharmaceutical Sciences

IF4.7

2025-12-04

OAAI

Yen-Ching Li; Bing-Huan Lin; Megumi Murakami; Yu-Shan Wu; Tai-Ho Hung; Suresh. V. Ambudkar; Chung-Pu Wu

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Nanoengineered photosensitizers for photodynamic priming to overcome P-glycoprotein-mediated multidrug resistance

PHOTOCHEMISTRY AND PHOTOBIOLOGY

IF2.5

2025-11-01

OAAI

Rahman, Idrisa; Meda, Anju; Moore, Kaitlyn A.; Srivastava, Payal; Dasgupta, Anika; Sajid, Andaleeb; Ambudkar, Suresh V.; Huang, Huang-Chiao

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The Fourth-Generation EGFR Tyrosine Kinase Inhibitor BLU-945 Resensitizes ABCG2-Overexpressing Multidrug-Resistant Non-Small Cell Lung Cancer Cells to Cytotoxic Anticancer Drugs

European Journal of Pharmaceutical Sciences

IF4.7

2025-10-19

OAAI

Yen-Ching Li; Bing-Huan Lin; Megumi Murakami; Yu-Shan Wu; Tai-Ho Hung; Suresh. V. Ambudkar; Chung-Pu Wu

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Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors

Bioorganic Chemistry

IF4.7

2025-09-05

PREAI

Abosede Salami; Ugochi Adiele; Griffin Coate; Morgan Diolaiti; Huadong Chen; Junhao Lu; Alan Ashworth; Manisha Patil; Joshua S. Fleishman; Andhavaram Ramaraju; Akanksha Patel; Himaxi Patel; Ketankumar Patel; Megumi Murakami; Suresh V. Ambudkar; Tanaji T. Talele

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Conversion of Human Multidrug Transporter P-glycoprotein (ABCB1) from Drug Efflux to Uptake Pump: Evidence for a Switch Region Modulating the Direction of Substrate Transport

JOURNAL OF MOLECULAR BIOLOGY

IF4.5

2025-04-01

PREAI

Sajid, Andaleeb; Ahmed, Shafaq; Ranganathan, Nandhini; Guha, Rajan; Murakami, Megumi; Durell, Stewart R.; Ambudkar, Suresh V.

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Vodobatinib overcomes cancer multidrug resistance by attenuating the drug efflux function of ABCB1 and ABCG2

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2025-02-01

PREAI

Li, Yen-Ching; Lin, Bing-Huan; Murakami, Megumi; Wu, Yu-Shan; Hung, Tai-Ho; Chen, Chin-Chuan; V. Ambudkar, Suresh; Wu, Chung-Pu

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Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier (vol 21,27,2024)

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2025-01-03

OAAI

Thomas, Joanna R.; Frye, William J. E.; Robey, Robert W.; Warner, Andrew C.; Butcher, Donna; Matta, Jennifer L.; Morgan, Tamara C.; Edmondson, Elijah F.; Salazar, Paula B.; Ambudkar, Suresh V.; Gottesman, Michael M.

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Editorial: ABC transporters and drug resistance

DRUG RESISTANCE UPDATES

IF21.7

2024-11-01

PREAI

Lu, Qisi; V. Ambudkar, Suresh; Yang, Dong-Hua

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Epertinib counteracts multidrug resistance in cancer cells by antagonizing the drug efflux function of ABCB1 and ABCG2

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-11-01

OAAI

Lin, Bing-Huan; Li, Yen-Ching; Murakami, Megumi; Wu, Yu-Shan; Huang, Yang-Hui; Hung, Tai-Ho; Ambudkar, Suresh. V.; Wu, Chung-Pu

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Reserpine analog modulates transport function of ABCG2

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Ohnuma, Shinobu; Kokubo, Shoji; Sugisawa, Norihiko; Murakami, Megumi; Hatsuzawa, Yuuri; Kobayashi, Minoru; Kajiwara, Taiki; Suzuki, Hideyuki; Karasawa, Hideaki; Watanabe, Kazuhiro; Doi, Takayuki; Ambudkar, Suresh V.; Kamei, Takashi; Unno, Michiaki

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Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2024-03-15

OAAI

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ABCB1-dependent collateral sensitivity of multidrug-resistant colorectal cancer cells to the survivin inhibitor MX106-4C

DRUG RESISTANCE UPDATES

IF21.7

2024-03-01

PREAI

Lei, Zi-Ning; Albadari, Najah; Teng, Qiu-Xu; Rahman, Hadiar; Wang, Jing-Quan; Wu, Zhongzhi; Ma, Dejian; V. Ambudkar, Suresh; Wurpel, John N. D.; Pan, Yihang; Li, Wei; Chen, Zhe-Sheng

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Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-02-01

OAAI

Gerard, Louise; Duvivier, Laurent; Fourrez, Marie; Salazar, Paula; Sprimont, Lindsay; Xia, Di; Ambudkar, Suresh, V; Gottesman, Michael M.; Gillet, Jean-Pierre

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Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport

PHARMACEUTICALS

IF4.8

2023-11-12

OAAI

Wu, Chung-Pu; Murakami, Megumi; Li, Yen-Ching; Huang, Yang-Hui; Chang, Yu-Tzu; Hung, Tai-Ho; Wu, Yu-Shan; Ambudkar, Suresh V.

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Research Directions