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Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy Garai, Sumanta; Leo, Luciana M.; Szczesniak, Anna-Maria; Hurst, Dow P.; Schaffer, Peter C.; Zagzoog, Ayat; Black, Tallan; Deschamps, Jeffrey R.; Miess, Elke; Schulz, Stefan; Janero, David R.; Straiker, Alex; Pertwee, Roger G.; Abood, Mary E.; Kelly, Melanie E. M.; Reggio, Patricia H.; Laprairie, Robert B.; Thakur, Ganesh A. Share Save
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Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators Garai, Sumanta; Kulkarni, Pushkar M.; Schaffer, Peter C.; Leo, Luciana M.; Brandt, Asher L.; Zagzoog, Ayat; Black, Tallan; Lin, Xiaoyan; Hurst, Dow P.; Janero, David R.; Abood, Mary E.; Zimmowitch, Anaelle; Straiker, Alex; Pertwee, Roger G.; Kelly, Melanie; Szczesniak, Anna-Maria; Denovan-Wright, Eileen M.; Mackie, Ken; Hohmann, Andrea G.; Reggio, Patricia H.; Laprairie, Robert B.; Thakur, Ganesh A. Share Save
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Human Cannabinoid Receptor 2 Ligand-Interaction Motif: Transmembrane Helix 2 Cysteine, C2.59(89), as Determinant of Classical Cannabinoid Agonist Activity and Binding Pose Zhou, Han; Peng, Yan; Halikhedkar, Aneetha; Fan, Pusheng; Janero, David R.; Thakur, Ganesh A.; Mercier, Richard W.; Sun, Xin; Ma, Xiaoyu; Makriyannis, Alexandros Share Save
Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor Laprairie, Robert B.; Kulkarni, Pushkar M.; Deschamps, Jeffrey R.; Kelly, Melanie E. M.; Janero, David R.; Cascio, Maria G.; Stevenson, Lesley A.; Pertwee, Roger G.; Kenakin, Terrence P.; Denovan-Wright, Eileen M.; Thakur, Ganesh A. Share Save
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Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe Laprairie, Robert B.; Kulkarni, Abhijit R.; Kulkarni, Pushkar M.; Hurst, Dow P.; Lynch, Diane; Reggio, Patricia H.; Janero, David R.; Pertwee, Roger G.; Stevenson, Lesley A.; Kelly, Melanie E. M.; Denovan-Wright, Eileen M.; Thakur, Ganesh A. Share Save
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Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s) Kulkarni, Pushkar M.; Kulkarni, Abhijit R.; Korde, Anisha; Tichkule, Ritesh B.; Laprairie, Robert B.; Denovan-Wright, Eileen M.; Zhou, Han; Janero, David R.; Zvonok, Nikolai; Makriyannis, Alexandros; Cascio, Maria G.; Pertwee, Roger G.; Thakur, Ganesh A. Share Save
Molecular-Interaction and Signaling Profiles of AM3677, a Novel Covalent Agonist Selective for the Cannabinoid 1 Receptor Janero, David R.; Yaddanapudi, Suma; Zvonok, Nikolai; Subramanian, Kumar V.; Shukla, Vidyanand G.; Stahl, Edward; Zhou, Lei; Hurst, Dow; Wager-Miler, James; Bohn, Laura M.; Reggio, Patricia H.; Mackie, Ken; Makriyannis, Alexandros Share Save
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