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SavePlasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS
Chatterjee, Madhurima; Ozdemir, Selcuk; Fritz, Christian; Mobius, Wiebke; Kleineidam, Luca; Mandelkow, Eckhard; Biernat, Jacek; Dogdu, Cem; Peters, Oliver; Cosma, Nicoleta Carmen; Wang, Xiao; Schneider, Luisa-Sophia; Priller, Josef; Spruth, Eike; Kuhn, Andrea A.; Krause, Patricia; Klockgether, Thomas; Vogt, Ina R.; Kimmich, Okka; Spottke, Annika; Hoffmann, Daniel C.; Fliessbach, Klaus; Miklitz, Carolin; McCormick, Cornelia; Weydt, Patrick; Falkenburger, Bjorn; Brandt, Moritz; Guenther, Rene; Dinter, Elisabeth; Wiltfang, Jens; Hansen, Niels; Bahr, Mathias; Zerr, Inga; Floel, Agnes; Nestor, Peter J.; Duzel, Emrah; Glanz, Wenzel; Incesoy, Enise; Burger, Katharina; Janowitz, Daniel; Perneczky, Robert; Rauchmann, Boris S.; Hopfner, Franziska; Wagemann, Olivia; Levin, Johannes; Teipel, Stefan; Kilimann, Ingo; Goerss, Doreen; Prudlo, Johannes; Gasser, Thomas; Brockmann, Kathrin; Mengel, David; Zimmermann, Milan; Synofzik, Matthis; Wilke, Carlo; Selma-Gonzalez, Judit; Turon-Sans, Janina; Santos-Santos, Miguel Angel; Alcolea, Daniel; Rubio-Guerra, Sara; Fortea, Juan; Carbayo, Alvaro; Lleo, Alberto; Rojas-Garcia, Ricardo; Illan-Gala, Ignacio; Wagner, Michael; Frommann, Ingo; Roeske, Sandra; Bertram, Lucas; Heneka, Michael T.; Brosseron, Frederic; Ramirez, Alfredo; Schmid, Matthias; Beschorner, Rudi; Halle, Annett; Herms, Jochen; Neumann, Manuela; Barthelemy, Nicolas R.; Bateman, Randall J.; Rizzu, Patrizia; Heutink, Peter; Dols-Icardo, Oriol; Hoeglinger, Guenter; Hermann, Andreas; Schneider, Anja Share Save Initiation and modulation of Tau protein phase separation by the drug suraminPrince, Prabhu Rajaiah; Hochmair, Janine; Brognaro, Hevila; Gevorgyan, Susanna; Franck, Maximilian; Schubert, Robin; Lorenzen, Kristina; Yazici, Selin; Mandelkow, Eckhard; Wegmann, Susanne; Betzel, Christian Share Save Share Save Unbiased proteomic profiling reveals the IP3R modulator AHCYL1/IRBIT as a novel interactor of microtubule-associated protein tauWischhof, Lena; Adhikari, Aasha; Mondal, Mrityunjoy; Marsal-Cots, Anaies; Biernat, Jacek; Mandelkow, Eva Maria; Mandelkow, Eckhard; Ehninger, Dan; Nicotera, Pierluigi; Bano, Daniele Share Save Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensatesHochmair, Janine; Exner, Christian; Franck, Maximilian; Dominguez-Baquero, Alvaro; Diez, Lisa; Brognaro, Hevila; Kraushar, Matthew L.; Mielke, Thorsten; Radbruch, Helena; Kaniyappan, Senthil; Falke, Sven; Mandelkow, Eckhard; Betzel, Christian; Wegmann, Susanne Share Save A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitroAillaud, Isabelle; Kaniyappan, Senthilvelrajan; Chandupatla, Ram Reddy; Ramirez, Lisa Marie; Alkhashrom, Sewar; Eichler, Jutta; Horn, Anselm H. C.; Zweckstetter, Markus; Mandelkow, Eckhard; Sticht, Heinrich; Funke, Susanne Aileen Share Save Share Save Share Save Share Save Share Save Share Save Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolutionUkmar-Godec, T.; Fang, P.; de Opakua, A. Ibanez; Henneberg, F.; Godec, A.; Pan, K-T; Cima-Omori, M-S; Chari, A.; Mandelkow, E.; Urlaub, H.; Zweckstetter, M. Share Save FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filamentsKaniyappan, Senthilvelrajan; Tepper, Katharina; Biernat, Jacek; Chandupatla, Ram Reddy; Huebschmann, Sabrina; Irsen, Stephan; Bicher, Sandra; Klatt, Christoph; Mandelkow, Eva-Maria; Mandelkow, Eckhard Share Save Lysine/RNA-interactions drive and regulate biomolecular condensationUkmar-Godec, Tina; Hutten, Saskia; Grieshop, Matthew P.; Rezaei-Ghaleh, Nasrollah; Cima-Omori, Maria-Sol; Biernat, Jacek; Mandelkow, Eckhard; Soeding, Johannes; Dormann, Dorothee; Zweckstetter, Markus Share Save Share Save Share Save Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease (vol 99, pg 925, 2018)Eftekharzadeh, Bahareh; Daigle, J. Gavin; Kapinos, Larisa E.; Coyne, Alyssa; Schiantarelli, Julia; Carlomagno, Yari; Cook, Casey; Miller, Sean J.; Dujardin, Simon; Amaral, Ana S.; Grima, Jonathan C.; Bennett, Rachel E.; Tepper, Katharina; DeTure, Michael; Vanderburg, Charles R.; Corjuc, Bianca T.; DeVos, Sarah L.; Gonzalez, Jose Antonio; Chew, Jeannie; Vidensky, Svetlana; Gage, Fred H.; Mertens, Jerome; Troncoso, Juan; Mandelkow, Eckhard; Salvatella, Xavier; Lim, Roderick Y. H.; Petrucelli, Leonard; Wegmann, Susanne; Rothstein, Jeffrey D.; Hyman, Bradley T. Share Save Share Save Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complexOroz, Javier; Chang, Bliss J.; Wysoczanski, Piotr; Lee, Chung-Tien; Perez-Lara, Angel; Chakraborty, Pijush; Hofele, Romina V.; Baker, Jeremy D.; Blair, Laura J.; Biernat, Jacek; Urlaub, Henning; Mandelkow, Eckhard; Dickey, Chad A.; Zweckstetter, Markus Share Save 
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