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Lukas Cyganek

German Center for Cardiovascular Research
H-index:26
Citation Count:2,547
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Improving optogenetic control over Gi/o-coupled receptor signaling by optimized GIRK channel expression

通过优化GIRK通道表达提高对Gi/o偶联受体信号的光遗传学控制

Science Signaling
IF6.6
2026-10-200
PRE
Brix Mücher; Aida Garrido-Charles; Jonas Wietek; Ina Köhler; Michelle Grömmke; Timo Frischmuth; Lukas Cyganek; Benjamin R. Rost; Tobias Bruegmann; Dietmar Schmitz; Deniz Dalkara; Petra Wahle; Ida Siveke; Stefan Herlitze
Variant U1 snRNAs contribute to cell cycle and differentiation control of human iPS cells

变体U1小核RNA参与人诱导多能干细胞的细胞周期和分化调控

Nature Communications
IF15.7
2026-05-130
OAAI
Yajie Zhu; Konstantinos Sofiadis; Athanasia Mizi; Vasilisa Kalinkina; Matthias Akyel; Milos Nikolic; Lukas Cyganek; Carmelo Ferrai; Argyris Papantonis
Cardiolipin remodeling in diabetic cardiomyopathy: Spotlight on ALCAT1

糖尿病心肌病中心肌脂质的重塑：聚焦ALCAT1

Molecular Therapy
IF12
2026-04-170
PRE
Carolin Knauer; Lukas Cyganek
SLC4A3-related short QT syndrome assessed in human induced pluripotent stem cell-derived cardiomyocytes: mechanisms of ventricular arrhythmia and sudden cardiac death

SLC4A3相关的短QT综合征在人类诱导多能干细胞来源的心肌细胞中的评估：室性心律失常和猝死的机制

European Heart Journal
IF35.6
2026-03-050
PRE
Zenghui Meng; Boldizsar Kovacs; Chen Yan; Christina Hölscher; Saltanat Zhazykbayeva; Oliver Jarkas; Chendan Zou; Lukas Cyganek; Esther Zorio; Aitana Braza-Boils; Juan Pablo Ochoa; Niels Rehbehn; Xuehui Fan; Xinhao Lei; Rui Liu; Siyuan Tong; Feng Liu; Zongqian Xue; Sara L Bober; Binyi Zhao; Firat Duru; Assem Aweimer; Alexandra Köppel; Karin Burau; Andreas Mügge; Wolfgang Berger; Nazha Hamdani; Xiaobo Zhou; Ardan M Saguner; Ibrahim Akin; Michael H Gollob; Ibrahim El-Battrawy
Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR

增强心肌细胞中的KLF15活性: 通过核酸酶缺陷型dCas9VPR预防病理性重编程和纤维化的新方法

Signal Transduction and Targeted Therapy
IF52.7
2026-03-030
OAAI
Eric Schoger; Rosa Kim; Federico Bleckwedel; Tomas Peralta; Laura Priesmeier; Janek Fischer; Laura Stengel; Cheila Rocha; Gabriela L. Santos; Susanne Lutz; Etienne Boileau; Nina Baumgarten; Marcel H. Schulz; Christoph Dieterich; Oliver J. Müller; Lukas Cyganek; Alfredo Cabrera-Orefice; Hanna Eberl; Christoph Maack; Katrin Streckfuss-Bömeke; Mario Pavez-Giani; Shirin Doroudgar; Samuel T. Sossalla; Laura C. Zelarayán
Improved Surface Properties and Enhanced Cell Adhesion on Poly-ε-Caprolactone for Heart Valve Tissue Engineering Applications via H2-N2 Plasma Treatment

通过H2-N2等离子体处理改善聚-ε-己内酯的表面性质并增强细胞粘附，以用于心脏瓣膜组织工程应用

International Journal of Molecular Sciences
IF4.9
2026-02-180
OA
Lutter, Georg; Schutrumpf, Julia; Seiler, Jette Anika; Jesaitis, Laura; Schneider, Viktor; Kersten, Holger; Hasler, Mario; Cyganek, Lukas; Book, Benjamin; Zhang, Xiling; Gorb, Stanislav N.; Sellers, Stephanie; Meier, David; Puehler, Thomas; Pommert, Nina; Frank, Derk; Nia, Monireh Saeid
Roles of Catecholamines and Inflammation in Endothelial Dysfunction: a Study Using Takotsubo Syndrome Patient-specific hiPSC-ECs

儿茶酚胺和炎症在血管内皮功能障碍中的作用：一项使用Tako-tsubo综合征患者特异性的hiPSC-ECs的研究

Stem Cell Reviews and Reports
IF4.2
2026-02-060
PRE
Guoqiang Yang; Luyi Zhong; Jiayue Wang; Chenyu Yang; Lukas Cyganek; Nazha Hamdani; Xiaobo Zhou; Xuehui Fan; Ibrahim El-Battrawy; Ibrahim Akin
Promoting differentiation of human-induced pluripotent stem cells into sinoatrial node-like cells through programmed regulation of AMPK signalling pathway

通过程序化调控AMPK信号通路促进人诱导多能干细胞向窦房结样细胞的分化

EUROPACE
IF7.4
2025-11-010
OAAI
Liu, Feng; Xue, Zongqian; Lan, Huan; Wan, Juyi; Yang, Chenyu; Cyganek, Lukas; Hamdani, Nazha; Yu, Fengxu; Liao, Bin; Zhou, Xiaobo; El-Battrawy, Ibrahim; Akin, Ibrahim
Automated patch-clamp for high throughput characterization of subtype-specific induced pluripotent stem cell derived cardiomyocytes

自动化膜片钳技术用于高通量表征亚型特异性诱导多能干细胞来源的心肌细胞

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
OAAI
Stoelzle-Feixa, Sonja; Seibertza, Fitzwilliam; Gerloffb, Marcus Lluis; Rapediusa, Markus; Liutkuteb, Aiste; Cyganekc, Lukas; Haarmanna, Claudia; Georgea, Michael; Voigtb, Niels; Fertiga, Niels
Exosomal mir-126-3p derived from endothelial cells induces ion channel dysfunction by targeting RGS3 signaling in cardiomyocytes: a novel mechanism in Takotsubo cardiomyopathy
STEM CELL RESEARCH & THERAPY
IF7.3
2025-02-040
OAAI
Fan, Xuehui; Yang, Guoqiang; Wang, Yinuo; Shi, Haojie; Nitschke, Katja; Sattler, Katherine; Abumayyaleh, Mohammad; Cyganek, Lukas; Nuhn, Philipp; Worst, Thomas; Liao, Bin; Dobreva, Gergana; Duerschmied, Daniel; Zhou, Xiaobo; El-Battrawy, Ibrahim; Akin, Ibrahim
Esophageal Cancer-Related Gene-4 Contributes to Lipopolysaccharide-Induced Ion Channel Dysfunction in hiPSC-Derived Cardiomyocytes
inflammation research
IF4.1
2024-12-010
OA
Xu, Qiang; Zhang, Xiangjie; Hao, Maolin; Dang, Xitong; Xu, Qianqian; Cyganek, Lukas; Akin, Ibrahim; Tang, Dan; Liao, Bin; Zhou, Xiaobo; Lan, Huan
CardioMEA: comprehensive data analysis platform for studying cardiac diseases and drug responses
FRONTIERS IN PHYSIOLOGY
IF3.4
2024-10-300
OAAI
Lee, Jihyun; Duperrex, Eliane; El-Battrawy, Ibrahim; Hohn, Alyssa; Saguner, Ardan M.; Duru, Firat; Emmenegger, Vishalini; Cyganek, Lukas; Hierlemann, Andreas; Ulusan, Hasan
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
CELL REPORTS
IF6.9
2024-07-012
OAAI
Busley, Alexandra Viktoria; Gutierrez-Gutierrez, Oscar; Hammer, Elke; Koitka, Fabian; Mirzaiebadizi, Amin; Steinegger, Martin; Pape, Constantin; Boehmer, Linda; Schroeder, Henning; Kleinsorge, Mandy; Engler, Melanie; Cirstea, Ion Cristian; Gremer, Lothar; Willbold, Dieter; Altmuller, Janine; Marbach, Felix; Hasenfuss, Gerd; Zimmermann, Wolfram-Hubertus; Ahmadian, Mohammad Reza; Wollnik, Bernd; Cyganek, Lukas
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants
MOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
2024-03-012
OAAI
Knauer, Carolin; Haltern, Henrike; Schoger, Eric; Kuegler, Sebastian; Roos, Lennart; Zelarayan, Laura C.; Hasenfuss, Gerd; Zimmermann, Wolfram-Hubertus; Wollnik, Bernd; Cyganek, Lukas
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development
CARDIOVASCULAR RESEARCH
IF13.3
2023-09-079
OAAI
Seibertz, Fitzwilliam; Rubio, Tony; Springer, Robin; Popp, Fiona; Ritter, Melanie; Liutkute, Aiste; Bartelt, Lena; Stelzer, Lea; Haghighi, Fereshteh; Pietras, Jan; Windel, Hendrik; Diaz i Pedrosa, Nuria; Rapedius, Markus; Doering, Yannic; Solano, Richard; Hindmarsh, Robin; Shi, Runzhu; Tiburcy, Malte; Bruegmann, Tobias; Kutschka, Ingo; Streckfuss-Boemeke, Katrin; Kensah, George; Cyganek, Lukas; Zimmermann, Wolfram H.; Voigt, Niels
Strain- induced Cardiac Arrhythmias Caused By A Noonan Syndrome Mutation In Raf1 Can Be Suppressed By Modulation Of The Rasmapk Pathway In Vitro
CIRCULATION RESEARCH
IF16.2
2023-08-040
PRE
Haghighi, Fereshteh; Boehmker, Leonie; Liutkute, Aiste; Kleemann, Karolin; Busley, Alexandra V.; Pietras, Jan P.; Fakaude, Funsho E.; Seibertz, Fitzwilliam; Rubio, Tony; Kutschka, Ingo; Zenker, Martin; Voigt, Niels; Cyganek, Lukas; Kensah, George
Impaired Calcium Homeostasis Underlies Lamin A/C Mutation R331Q Associated Atrial Fibrillation
CIRCULATION RESEARCH
IF16.2
2023-08-040
PRE
Liutkute, Aiste; Pavez-Giani, Mario; Sobitov, Izzatullo; van Wijk, Stan; Sossalla, Samuel; Cyganek, Lukas; Brundel, Bianca J. Jjm; Voigt, Niels
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome

在Barth综合征的敲入小鼠模型中，从脂肪酸氧化到糖酵解的代谢转换

EMBO MOLECULAR MEDICINE
IF8.3
2023-08-035
OAAI
Chowdhury, Arpita; Boshnakovska, Angela; Aich, Abhishek; Methi, Aditi; Leon, Ana Maria Vergel; Silbern, Ivan; Luechtenborg, Christian; Cyganek, Lukas; Prochazka, Jan; Sedlacek, Radislav; Lindovsky, Jiri; Wachs, Dominic; Nichtova, Zuzana; Zudova, Dagmar; Koubkova, Gizela; Fischer, Andre; Urlaub, Henning; Bruegger, Britta; Katschinski, Doerthe M.; Dudek, Jan; Rehling, Peter
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues
COMMUNICATIONS BIOLOGY
IF5.1
2023-06-2113
OAAI
Nakhaei-Rad, Saeideh; Haghighi, Fereshteh; Bazgir, Farhad; Dahlmann, Julia; Busley, Alexandra Viktoria; Buchholzer, Marcel; Kleemann, Karolin; Schaenzer, Anne; Borchardt, Andrea; Hahn, Andreas; Koetter, Sebastian; Schanze, Denny; Anand, Ruchika; Funk, Florian; Kronenbitter, Annette Vera; Scheller, Juergen; Piekorz, Roland P.; Reichert, Andreas S.; Volleth, Marianne; Wolf, Matthew J.; Cirstea, Ion Cristian; Gelb, Bruce D.; Tartaglia, Marco; Schmitt, Joachim P.; Krueger, Martina; Kutschka, Ingo; Cyganek, Lukas; Zenker, Martin; Kensah, George; Ahmadian, Mohammad R.
Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes

人诱导多能干细胞来源的心肌细胞长期培养过程中的电生理和钙处理发育

BASIC RESEARCH IN CARDIOLOGY
IF8
2023-04-0516
OAAI
Seibertz, Fitzwilliam; Sutanto, Henry; Duelk, Rebekka; Pronto, Julius Ryan D.; Springer, Robin; Rapedius, Markus; Liutkute, Aiste; Ritter, Melanie; Jung, Philipp; Stelzer, Lea; Huesgen, Luisa M.; Klopp, Marie; Rubio, Tony; Fakuade, Funsho E.; Mason, Fleur E.; Hartmann, Nico; Pabel, Steffen; Streckfuss-Boemeke, Katrin; Cyganek, Lukas; Sossalla, Samuel; Heijman, Jordi; Voigt, Niels

Research Directions

The data has not been retrieved yet.
I
Ibrahim El‐Battrawy
H-index:41Papers:370Citations:6,168
X
Xiaobo Zhou
H-index:31Papers:154Citations:2,941
İ
İbrahim Akın
H-index:51Papers:878Citations:1.5万
H
Huan Lan
H-index:17Papers:55Citations:1,047
W
Wolfram‐Hubertus Zimmermann
H-index:54Papers:283Citations:1.1万
S
Siegfried Lang
H-index:39Papers:328Citations:5,464
T
Thomas Wieland
H-index:75Papers:471Citations:2.4万
M
Martin Borggrefe
H-index:65Papers:501Citations:2.1万
J
Jochen Utikal
H-index:87Papers:908Citations:4.5万
G
Gerd Hasenfuß
H-index:107Papers:1,765Citations:5.4万