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SaveCrystal packing modifies ligand binding affinity: The case of aldose reductase
Cousido-Siah, Alexandra; Petrova, Tatiana; Hazemann, Isabelle; Mitschler, Andre; Ruiz, Francesc X.; Howard, Eduardo; Ginell, Stephan; Atmanene, Cedric; Van Dorsselaer, Alain; Sanglier-Cianferani, Sarah; Joachimiak, Andrzej; Podjarny, Alberto
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SaveFactorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex
Petrova, T; Steuber, H; Hazemann, I; Cousido-Siah, A; Mitschler, A; Chung, R; Oka, M; Icebe, G; El-Kabbani, O; Joachimiak, A; Podjarny, A
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SaveDiscovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (Lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
Van Zandt, MC; Jones, ML; Gunn, DE; Geraci, LS; Jones, JH; Sawicki, DR; Sredy, J; Jacot, JL; DiCioccio, AT; Petrova, T; Mitschler, A; Podjarny, AD
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