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Alex Sparreboom

University System of Ohio

98H-index
842Paper Count
3.1WCitation Count
Published Papers 192
Publication Date
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Zebrafish as a Model Organism of Decitabine-Induced Myelotoxicity
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errHam, Alexander; Anabtawi, Nadeen; Oyman, Konur; Orwick, Shelley; Buelow, Daelynn R.; Sparreboom, Alex; Blaser, Bradley W.; Baker, Sharyn
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Environmental Pollutant PFOS Identified in Untargeted Metabolomics as a Dual Oatp1b Substrate and Inhibitor: Implications for DDI Risk
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errChowdhury, Anika; Ahmed, Eman; Li, Yang Y. L.; Fetsko, Brian; Orwick, Shelley; Drabison, Thomas; Yang, Yan; Cheng, Xioalin; Sparreboom, Alex; Hu, Shuiying
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errSave
A Cardiac-Specific Humanized Mouse Model to Evaluate the Disposition of OCT3 Substrates
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errBoeckman, Mike; Bohnert, Regina; Ahmed, Bagdad; Talebi, Zahra; Ahmed, Eman; Zahedimaram, Pegah; Lemen, Lisa; Wang, Xiangning; Hertlein, Erin; Baker, Sharyn; Addison, Daniel; Schaeffeler, Elke; Schwab, Matthias; Nies, Anne T.; Sparreboom, Alex; Huang, Kevin M.
errShare
errSave
OATP1B2 Deficiency Aggravates Docetaxel-Induced Neutropenia in a Translationally Relevant Mouse Model
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errSteiger, Brandon; Buelow, Daelynn R.; Curry, Jack; Orwick, Shelley; Sparreboom, Alex; Baker, Sharyn; Hu, Shuiying
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errSave
Formulation-Dependent Hepatocellular Transport of Taxanes by OATP1B2: Implications for Drug-Drug Interaction Liabilities With Taxol and Abraxane
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errKleinert, Nicholas; Wang, Xinye; Xu, Yue; Ahmed, Eman; Peterson, Blake r.; Sparreboom, Alex; Hu, Shuiying
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errSave
The Novel OCT3 Inhibitor Peficitinib Attenuates Doxorubicin-Induced Cardiotoxicity
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errBoeckman, Mike; Ahmed, Bagdad; Lin, Zhihong; Kumar, Damu Sunil; Ahmed, Eman; Curry, John; Ham, Alexander; Islam, Mohammad N.; Kooti, Fatemeh; Sitte, Harald; Stockner, Thomas; Corps, Kara; Wu, Meng; Peterson, Blake; Baker, Sharyn; Addison, Daniel; Sparreboom, Alex; Huang, Kevin M.
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errSave
Elucidating the Role of S100A9 in Paclitaxel-Induced Peripheral Neuropathy
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errWang, Ke; Drabison, Thomas; Buelow, Daelynn; Salunkhe, Amruta; Garrity, Katy; Wang, Xinye; Baker, Sharyn D.; Hu, Shuiying; Sparreboom, Alex; Hammond, Luke; Shin, Grace; Eisenmann, Eric D.
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errSave
Development of a Translationally Relevant Strategy to Protect Against Paclitaxel-Induced Peripheral Neuropathy
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errWang, Xinye; Drabison, Thomas; Wang, Ke; Salunkhe, Amruta; Garrity, Katy; Hu, Shuiying; Baker, Sharyn D.; Sparreboom, Alex; Hammond, Luke; Shin, Grace; Eisenmann, Eric D.
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errSave
Ribociclib is not a substrate or inhibitor of Oatp1b-mediated uptake in vivo
errCancer Chemotherapy and Pharmacology
IF2.3
err2026-04-07
err0
errOAAI
errThomas Drabison; Eman A. Ahmed; Nathan Colasanti; Robert H. Weber; Alex Sparreboom; Eric D. Eisenmann
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errSave
Pacific Blue Derivatives of Paclitaxel as Fluorescent Probes of OATP1B-Type Transporters
errClinical and Translational Science
IF2.8
err2026-01-27
err0
errOAAI
errMahesh R. Nepal; Yue Xu; Yan Jin; Peng Hu; Xiaojun Hu; Digamber S. Rane; Angelo E. Andres; Eman A. Ahmed; Brandon Steiger; Alex Sparreboom; Blake R. Peterson; Shuiying Hu
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errSave
Role of SLC transporters in the biodistribution and toxicity of chemotherapeutic drugs
errPharmacological Reviews
IF17.3
err2026-01-16
err0
errOAAI
errMike Boeckman; Thomas Drabison; Arthur Germakovski; Allison Warmuth; Bagdad Ahmed; Anika Chowdhury; Shuiying Hu; Jason A. Sprowl; Alex Sparreboom; Kevin M. Huang
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errSave
OATP2B1 Deficiency Ameliorates Irinotecan-Induced Gastrointestinal Toxicity
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2025-12-29
err0
errOAAI
errTaheri, Hanieh; de Bruijn, Peter; Li, Yang; Kleinert, Nicholas R.; Corps, Kara N.; Mathijssen, Ron H. J.; Huang, Kevin M.; Sparreboom, Alex; Hu, Shuiying
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errSave
Drug–drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors
errExpert Review of Clinical Pharmacology
IF3
err2025-12-24
err0
errOAAI
errJack C. Stromatt; Anika T. Chowdhury; Kevin M. Huang; Shuiying Hu; Alex Sparreboom; Sharyn D. Baker; Eric D. Eisenmann
errShare
errSave
Regulation of hepatic OATP1B-type transport function by the protein kinase LYN
errDrug Metabolism and Disposition
IF4
err2025-07-30
err0
PREAI
errVivian Xu; Mahesh R. Nepal; Eman Ahmed; Benjamin D. Kaczynski; Yue Xu; James M. Gallo; Kevin M. Huang; Alex Sparreboom; Shuiying Hu; Jason A. Sprowl
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errSave
Determination and Disposition of the Aromatase Inhibitor Exemestane in CYP3A-Deficient Mice
errMOLECULES
IF4.6
err2025-03-24
err0
errOAAI
errTaheri, Hanieh; Ahmed, Eman; Hu, Peng; Sparreboom, Alex; Hu, Shuiying
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errSave
AML-Dependent Transcriptional Repression of Hepatic Transporters
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errStromatt, Jack C.; Orwick, Shelley; Buelow, Daelynn R.; Pabla, Navjot S.; Sparreboom, Alex; Baker, Sharyn D.
errShare
errSave
P-glycoprotein (P-gp) Deficiency Exacerbates Vincristine-Induced Peripheral Neuropathy
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errChowdhury, Anika; Drabison, Thomas; Ahmed, Eman; Buelow, Daelynn R.; Peterson, Blake R.; Huang, Kevin M.; Eisenmann, Eric D.; Kulkarni, Chetan P.; Kroetz, Deanna; Baker, Sharyn D.; Sparreboom, Alex; Hu, Shuying
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errSave
Interaction of Neuropathic Tubulin Poison Payloads with OATP1B-type Transporters
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errHuang, Kevin; Jakate, Anushree; Partey, Alexandra; Hu, Shuying; Sparreboom, Alex
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errSave
Identification of OCT3 Inhibitors for Preventing Cardiac Accumulation of Toxic Substrates
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errBoeckman, Mike; Lin, Zhihong; Huang, Kevin M.; Steenrod, Levi; Wu, Meng; Peterson, Blake R.; Baker, Sharyn D.; Addison, Daniel; Sparreboom, Alex
errShare
errSave
Targeting S100A9 to Protect Against Paclitaxel-Induced Peripheral Neuropathy
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errDrabison, Thomas; Li, Yang; Buelow, Daelynn R.; Ahmed, Eman; Colasanti, Nathan; Lopatin, Sergey; Baker, Sharyn D.; Hu, Shuiying; Sparreboom, Alex; Eisenmann, Eric D.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Mary V. Relling
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Jos H. Beijnen
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A
Andrej Săli
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