Not logged inReal-time evaluation of macozinone activity against Mycobacterium tuberculosis through bacterial nanomotion analysis
Vocat, Anthony; Luraschi-Eggemann, Amanda; Antoni, Claudia; Cathomen, Gino; Cichocka, Danuta; Greub, Gilbert; Riabova, Olga; Makarov, Vadim; Opota, Onya; Mendoza, Alfonso; Cole, Stewart T.; Sturm, Alexander .png)
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SaveDiscovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active Against Multidrug Resistant TuberculosisDashti, Yousef; Mohammadipanah, Fatemeh; Zhang, Yu; Cerqueira Diaz, Pietra M.; Vocat, Anthony; Zabala, Daniel; Fage, Christopher D.; Romero-Canelon, Isolda; Bunk, Boyke; Sproer, Cathrin; Alkhalaf, Lona M.; Overmann, Joerg; Cole, Stewart T.; Challis, Gregory L. Share Save Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation PathwayKarabanovich, Galina; Fabianova, Viktoria; Vocat, Anthony; Dusek, Jan; Valaskova, Lenka; Stolarikova, Jirina; Kitson, Russell R. A.; Pavek, Petr; Vavrova, Katerina; Djaout, Kamel; Mikusova, Katarina; Baulard, Alain R.; Cole, Stewart T.; Kordulakova, Jana; Roh, Jaroslav Share Save Synthesis and In Vitro Biological Evaluation of Quinolinyl Pyrimidines Targeting Type II NADH-Dehydrogenase (NDH-2)Lu, Lu; Akerbladh, Linda; Ahmad, Shabbir; Konda, Vivek; Cao, Sha; Vocat, Anthony; Maes, Louis; Cole, Stewart T.; Hughes, Diarmaid; Larhed, Mats; Brandt, Peter; Karlen, Anders; Mowbray, Sherry L. Share Save Development and validation of a multiplex real-time qPCR assay using GMP-grade reagents for leprosy diagnosisManta, Fernanda Saloum de Neves; Jacomasso, Thiago; Pontello Rampazzo, Rita de Cassia; Moreira, Suelen Justo Maria; Zahra, Najua; Cole, Stewart; Avanzi, Charlotte; Leal-Calvo, Thyago; Vasconcellos, Sidra Ezidio Goncalves; Suffys, Phillip; Ribeiro-Alves, Marcelo; Krieger, Marco Aurelio; Costa, Alexandre Dias Tavares; Moraes, Milton Ozorio Share Save Share Save Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial ActivityMonakhova, Natalia; Kordulakova, Jana; Vocat, Anthony; Egorova, Anna; Lepioshkin, Alexander; Salina, Elena G.; Nosek, Jozef; Repkova, Eva; Zemanova, Julia; Jurdakova, Helena; Gorova, Renata; Roh, Jaroslav; Degiacomi, Giulia; Sammartino, Jose Camilla; Pasca, Maria Rosalia; Cole, Stewart T.; Mikusova, Katarina; Makarov, Vadim Share Save FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence of Mycobacterium tuberculosisMondino, Sonia; Vazquez, Cristina L.; Cabruja, Matias; Sala, Claudia; Cazenave-Gassiot, Amaury; Blanco, Federico C.; Wenk, Markus R.; Bigi, Fabiana; Cole, Stewart T.; Gramajo, Hugo; Gago, Gabriela Share Save 6,11-Dioxobenzo[f]pyrido[1,2-a]indoles Kill Mycobacterium tuberculosis by Targeting Iron-Sulfur Protein Rv0338c (IspQ), A Putative Redox SensorSzekely, Rita; Rengifo-Gonzalez, Monica; Singh, Vinayak; Riabova, Olga; Benjak, Andrej; Piton, Jeremie; Cimino, Mena; Kornobis, Etienne; Mizrahi, Valerie; Johnsson, Kai; Manina, Giulia; Makarov, Vadim; Cole, Stewart T. Share Save Share Save Emergence of Mycobacterium leprae Rifampin Resistance Evaluated by Whole-Genome Sequencing after 48 Years of Irregular TreatmentAvanzi, Charlotte; Maia, Raquel Cristina; Benjak, Andrej; Nery, Jose Augusto; Sales, Anna Maria; Miranda, Alice; Duppre, Nadia Cristina; Fontes, Amanda Nogueira Brum; da Silva, Tatiana Pereira; Pinheiro, Roberta Olmo; Neves-manta, Fernanda; Moreira, Suelen Justo Maria; Busso, Philippe; Sarno, Euzenir Nunes; Suffys, Phillip Noel; Cole, Stewart Thomas; Moraes, Milton Ozorio Share Save Genomic Characterization ofMycobacterium lepraeto Explore Transmission Patterns Identifies New Subtype in BangladeshTio-Coma, Maria; Avanzi, Charlotte; Verhard, Els M.; Pierneef, Louise; van Hooij, Anouk; Benjak, Andrej; Roy, Johan Chandra; Khatun, Marufa; Alam, Khorshed; Corstjens, Paul; Cole, Stewart T.; Richardus, Jan Hendrik; Geluk, Annemieke Share Save Population Genomics of Mycobacterium leprae Reveals a New Genotype in Madagascar and the ComorosAvanzi, Charlotte; Lecorche, Emmanuel; Rakotomalala, Fetra Angelot; Benjak, Andrej; Rabenja, Fahafahantsoa Rapelanoro; Ramarozatovo, Lala S.; Cauchoix, Bertrand; Rakoto-Andrianarivelo, Mala; Tio-Coma, Maria; Leal-Calvo, Thyago; Busso, Philippe; Boy-Roettger, Stefanie; Chauffour, Aurelie; Rasamoelina, Tahinamandrato; Andrianarison, Aina; Sendrasoa, Fandresena; Spencer, John S.; Singh, Pushpendra; Dashatwar, Digambar Ramchandra; Narang, Rahul; Berland, Jean-Luc; Jarlier, Vincent; Salgado, Claudio G.; Moraes, Milton O.; Geluk, Annemieke; Randrianantoandro, Andriamira; Cambau, Emmanuelle; Cole, Stewart T. Share Save Structural and DNA binding properties of mycobacterial integration host factor mIHFOdermatt, Nina T.; Lelli, Moreno; Herrmann, Torsten; Abriata, Luciano A.; Japaridze, Aleksandre; Voilquin, Hubert; Singh, Rajkumar; Piton, Jeremie; Emsley, Lyndon; Dietler, Giovanni; Cole, Stewart T. Share Save New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosisLupien, Andreanne; Foo, Caroline Shi-Yan; Savina, Svetlana; Vocat, Anthony; Piton, Jeremie; Monakhova, Natalia; Benjak, Andrej; Lamprecht, Dirk A.; Steyn, Adrie J. C.; Pethe, Kevin; Makarov, Vadim A.; Cole, Stewart T. Share Save Synthesis and Structure-Activity Relationship Studies of C2-Modified Analogs of the Antimycobacterial Natural Product PyridomycinKienle, Maryline; Eisenring, Patrick; Stoessel, Barbara; Horlacher, Oliver P.; Hasler, Samuel; van Colen, Gwenaelle; Hartkoorn, Ruben C.; Vocat, Anthony; Cole, Stewart T.; Altmann, Karl-Heinz Share Save Share Save Share Save Synthesis, biology, computational studies and in vitro controlled release of new isoniazid-based adamantane derivativesPapageorgiou, Andria; Foscolos, Angeliki-Sofia; Papanastasiou, Ioannis P.; Vlachou, Marilena; Siamidi, Angeliki; Vocat, Anthony; Cole, Stewart T.; Kellici, Tahsin F.; Mavromoustakos, Thomas; Tsotinis, Andrew Share Save Share Save 
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