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Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells Wang, Zihao; Thakare, Ritesh P.; Chitale, Shalaka; Mishra, Alok K.; Goldstein, Stanley I.; Fan, Alice C.; Li, Rui; Zhu, Lihua Julie; Brown, Lauren E.; Cencic, Regina; Huang, Sidong; Green, Michael R.; Pelletier, Jerry; Malonia, Sunil K.; Porco, John A. Share Save
A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer Cencic, Regina; Im, Young K.; Naineni, Sai Kiran; Moustafa-Kamal, Mohamed; Jovanovic, Predrag; Sabourin, Valerie; Annis, Matthew G.; Robert, Francis; Schmeing, T. Martin; Koromilas, Antonis; Paquet, Marilene; Teodoro, Jose G.; Huang, Sidong; Siegel, Peter M.; Topisirovic, Ivan; Ursini-Siegel, Josie; Pelletier, Jerry Share Save
Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations Aksoylu, Inci S.; Martin, Pauline; Robert, Francis; Szkop, Krzysztof J.; Redmond, Nicholas E.; Bhattacharyya, Srirupa; Wang, Jennifer; Chen, Shan; Beauchamp, Roberta L.; Nobeli, Irene; Pelletier, Jerry; Larsson, Ola; Ramesh, Vijaya Share Save
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Exploring the targeting spectrum of rocaglates among eIF4A homologs Naineni, Sai Kiran; Cencic, Regina; Robert, Francis; Brown, Lauren E.; Haque, Minza; Scott-Talib, Jordan; Senechal, Patrick; Schmeing, T. Martin; Porco, John A.; Pelletier, Jerry Share Save
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Evolution of naturally arising SARS-CoV-2 defective interfering particles Girgis, Samer; Xu, Zaikun; Oikonomopoulos, Spyros; Fedorova, Alla D.; Tchesnokov, Egor P.; Gordon, Calvin J.; Schmeing, T. Martin; Goette, Matthias; Sonenberg, Nahum; Baranov, Pavel, V; Ragoussis, Jiannis; Hobman, Tom C.; Pelletier, Jerry Share Save
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation Xu, Zhang; Choi, Jung-Hyun; Dai, David L.; Luo, Jun; Ladak, Reese Jalal; Li, Qian; Wang, Yimeng; Zhang, Christine; Wiebe, Shane; Liu, Alex C. H.; Ran, Xiaozhuo; Yang, Jiaqi; Naeli, Parisa; Garzia, Aitor; Zhou, Lele; Mahmood, Niaz; Deng, Qiyun; Elaish, Mohamed; Lin, Rongtuan; Mahal, Lara K.; Hobman, Tom C.; Pelletier, Jerry; Alain, Tommy; Vidal, Silvia M.; Duchaine, Thomas; Mazhab-Jafari, Mohammad T.; Mao, Xiaojuan; Jafarnejad, Seyed Mehdi; Sonenberg, Nahum Share Save
Inhibition of the Translation Initiation Factor eIF4A Enhances Tumor Cell Radiosensitivity Lehman, Stacey L.; Wechsler, Theresa; Schwartz, Kayla; Brown, Lauren E.; Porco, John A., Jr.; Devine, William G.; Pelletier, Jerry; Shankavaram, Uma T.; Camphausen, Kevin; Tofilon, Philip J. Share Save
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Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice Abusarah, Jamilah; Khodayarian, Fatemeh; El-Hachem, Nehme; Salame, Natasha; Olivier, Martin; Balood, Mohammad; Roversi, Katiane; Talbot, Sebastien; Bikorimana, Jean-Pierre; Chen, Jingkui; Jolicoeur, Mario; Trudeau, Louis-Eric; Kamyabiazar, Samaneh; Annabi, Borhane; Robert, Francis; Pelletier, Jerry; El-Kadiry, Abed-El-Hakim; Shammaa, Riam; Rafei, Moutih Share Save
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A forward genetic screen identifies modifiers of rocaglate responsiveness Shen, Leo; Pugsley, Lauren; Cencic, Regina; Wang, HanChen; Robert, Francis; Naineni, Sai Kiran; Sahni, Ananya; Morin, Genevieve; Zhang, Wenhan; Nijnik, Anastasia; Porco, John A., Jr.; Langlais, David; Huang, Sidong; Pelletier, Jerry Share Save
Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A Naineni, Sai Kiran; Liang, Jason; Hull, Kenneth; Cencic, Regina; Zhu, Mingzhao; Northcote, Peter; Teesdale-Spittle, Paul; Romo, Daniel; Nagar, Bhushan; Pelletier, Jerry Share Save
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Eukaryotic Translation Initiation Factor 4AI: A Potential Novel Target in Neuroblastoma Skofler, Christina; Kleinegger, Florian; Krassnig, Stefanie; Birkl-Toeglhofer, Anna Maria; Singer, Georg; Till, Holger; Benesch, Martin; Cencic, Regina; Porco, John A., Jr.; Pelletier, Jerry; Castellani, Christoph; Raicht, Andrea; Izycka-Swieszewska, Ewa; Czapiewski, Piotr; Haybaeck, Johannes Share Save
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