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The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells Wolf, Gernot; Craigon, Conner; Teoh, Shao Thing; Essletzbichler, Patrick; Onstein, Svenja; Cassidy, Diane; Uijttewaal, Esther C. H.; Dvorak, Vojtech; Cao, Yuting; Bensimon, Ariel; Elling, Ulrich; Ciulli, Alessio; Superti-Furga, Giulio Share Save
Human genetic variants in SLC39A8 impact uptake and steady-state metal levels within the cell Wang, Wen-An; Garofoli, Andrea; Ferrada, Evandro; Klimek, Christoph; Steurer, Barbara; Ingles-Prieto, Alvaro; Osthushenrich, Tanja; Macnamara, Aidan; Malarstig, Anders; Wiedmer, Tabea; Superti-Furga, Giulio Share Save
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Image-based quantification of mitochondrial iron uptake via Mitoferrin-2 Polesel, Marcello; Wildschut, Mattheus H. E.; Doucerain, Cedric; Kuhn, Michael; Flace, Anna; Zanetti, Leandro Sa; Steck, Anna -Lena; Wilhelm, Maria; Ingles-Prieto, Alvaro; Wiedmer, Tabea; Superti-Furga, Giulio; Manolova, Vania; Durrenberger, Franz Share Save
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AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells Hellweg, Lars; Pfeifer, Martin; Tarnawski, Miroslaw; Thing-Teoh, Shao; Chang, Lena; Bergner, Andrea; Kress, Jana; Hiblot, Julien; Wiedmer, Tabea; Superti-Furga, Giulio; Reinhardt, Jueurorgen; Johnsson, Kai; Leippe, Philipp Share Save
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP Cigler, Marko; Imrichova, Hana; Frommelt, Fabian; Caramelle, Lucie; Depta, Laura; Rukavina, Andrea; Kagiou, Chrysanthi; Hannich, J. Thomas; Mayor-Ruiz, Cristina; Superti-Furga, Giulio; Sievers, Sonja; Forrester, Alison; Laraia, Luca; Waldmann, Herbert; Winter, Georg E. Share Save
EU-LIFE charter of independent life science research institutes Superti-Furga, Giulio; Agostinho, Marta; Bury, Jo; Cook, Simon; Durinx, Christine; Ender, Anita; van Luenen, Henri; Lund, Anders H.; Medema, Rene H.; Miaczynska, Marta; Nickel, Dorthe; Pelicci, Pier Giuseppe; Puisieux, Alain; Ripatti, Samuli; Sander, Maike; Schubeler, Dirk; Serrano, Luis; Sommer, Thomas; Sonne-Hansen, Katrine; Tomancak, Pavel; Vives, Joan; Vontas, John; Bettencourt-Dias, Monica Share Save
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling Ng, Amanda; Offensperger, Fabian; Cisneros, Jose A.; Scholes, Natalie S.; Malik, Monika; Villanti, Ludovica; Rukavina, Andrea; Ferrada, Evandro; Hannich, J. Thomas; Koren, Anna; Kubicek, Stefan; Superti-Furga, Giulio; Winter, Georg E. Share Save
Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling Chen, Xudong; Xie, Min; Zhang, Sensen; Monguio-Tortajada, Marta; Yin, Jian; Liu, Chang; Zhang, Youqi; Delacretaz, Maeva; Song, Mingyue; Wang, Yixue; Dong, Lin; Ding, Qiang; Zhou, Boda; Tian, Xiaolin; Deng, Haiteng; Xu, Lina; Liu, Xiaohui; Yang, Zi; Chang, Qing; Na, Jie; Zeng, Wenwen; Superti-Furga, Giulio; Rebsamen, Manuele; Yang, Maojun Share Save
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity Boeszoermenyi, Andras; Bernaleau, Lea; Chen, Xudong; Kartnig, Felix; Xie, Min; Zhang, Haobo; Zhang, Sensen; Delacretaz, Maeva; Koren, Anna; Hopp, Ann-Katrin; Dvorak, Vojtech; Kubicek, Stefan; Aletaha, Daniel; Yang, Maojun; Rebsamen, Manuele; Heinz, Leonhard X.; Superti-Furga, Giulio Share Save
Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels Gueldenpfennig, Anka; Hopp, Ann-Katrin; Muskalla, Lukas; Manetsch, Patrick; Raith, Fabio; Hellweg, Lars; Doerdelmann, Cyril; Pedrioli, Deena M. Leslie; Johnsson, Kai; Superti-Furga, Giulio; Hottiger, Michael O. Share Save
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Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors Dvorak, Vojtech; Casiraghi, Andrea; Colas, Claire; Koren, Anna; Tomek, Tatjana; Offensperger, Fabian; Rukavina, Andrea; Tin, Gary; Hahn, Elisa; Dobner, Sarah; Frommelt, Fabian; Boeszoermenyi, Andras; Bernada, Viktoriia; Hannich, Thomas; Ecker, Gerhard F.; Winter, Georg E.; Kubicek, Stefan; Superti-Furga, Giulio Share Save
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