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Comprehensive metabolomics combined with machine learning for the identification of SARS-CoV-2 and other viruses directly from upper respiratory samples Hogan, Catherine A.; Le, Anthony T.; Khan, Afraz; Su, LingHui David; Huang, Chunhong; Sahoo, Malaya K.; Lo, Chieh-Wen; Karim, Marwah; Stein, Karin Ann; Einav, Shirit; Cowan, Tina M.; Pinsky, Benjamin A. Share Save
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Synthesis of 3-heteroaryl-pyrrolo[2,3-b]pyridines as potent inhibitors of AP-2-associated protein kinase 1 (AAK1) with antiviral activity Ravi, Nitha Panikkassery; Van Eynde, Wout; Karim, Marwah; Tran, Do Hoang Nhu; Agrawal, Aditi; Schols, Dominique; Voet, Arnout; Einav, Shirit; Dehaen, Wim; De Jonghe, Steven Share Save
Numb-associated kinases regulate sandfly-borne Toscana virus entry Moalem, Yarden; Katz, Rodolfo; Subramaniam, Anand G.; Malis, Yehonathan; Yaffe, Yakey; Borenstein-Auerbach, Nofit; Tadmor, Keshet; Raved, Roey; Maoz, Ben M.; Yoo, Ji Seung; Lustig, Yaniv; Luxenburg, Chen; Perlson, Eran; Einav, Shirit; Sklan, Ella H. Share Save
Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors Gerninghaus, Joshua; Zhubi, Rezart; Kra''mer, Andreas; Karim, Marwah; Tran, Do Hoang Nhu; Joerger, Andreas C.; Schreiber, Christian; Berger, Lena M.; Berger, Benedict-Tilman; Ehret, Theresa A. L.; Elson, Lewis; Lenz, Christopher; Saxena, Krishna; Mu''ller, Susanne; Einav, Shirit; Knapp, Stefan; Hanke, Thomas Share Save
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations Westberg, Michael; Su, Yichi; Zou, Xinzhi; Huang, Pinghan; Rustagi, Arjun; Garhyan, Jaishree; Patel, Puja Bhavesh; Fernandez, Daniel; Wu, Yan; Hao, Chenzhou; Lo, Chieh-Wen; Karim, Marwah; Ning, Lin; Beck, Aimee; Saenkham-Huntsinger, Panatda; Tat, Vivian; Drelich, Aleksandra; Peng, Bi-Hung; Einav, Shirit; Tseng, Chien-Te K.; Blish, Catherine; Lin, Michael Z. Share Save
Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans Ratnasiri, Kalani; Zheng, Hong; Toh, Jiaying; Yao, Zhiyuan; Duran, Veronica; Donato, Michele; Roederer, Mario; Kamath, Megha; Todd, John-Paul M.; Gagne, Matthew; Foulds, Kathryn E.; Francica, Joseph R.; Corbett, Kizzmekia S.; Douek, Daniel C.; Seder, Robert A.; Einav, Shirit; Blish, Catherine A.; Khatri, Purvesh Share Save
Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach Ghita, Luca; Yao, Zhiyuan; Xie, Yike; Duran, Veronica; Cagirici, Halise Busra; Samir, Jerome; Osman, Ilham; Rebellon-Sanchez, David Esteban; Agudelo-Rojas, Olga Lucia; Sanz, Ana Maria; Sahoo, Malaya Kumar; Robinson, Makeda L.; Gelvez-Ramirez, Rosa Margarita; Bueno, Nathalia; Luciani, Fabio; Pinsky, Benjamin A.; Montoya, Jose G.; Estupinan-Cardenas, Maria Isabel; Villar-Centeno, Luis Angel; Rojas-Garrido, Elsa Marina; Rosso, Fernando; Quake, Stephen R.; Zanini, Fabio; Einav, Shirit Share Save
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses Lubow, Jay; Levoir, Lisa M.; Ralph, Duncan K.; Belmont, Laura; Contreras, Maya; Cartwright-Acar, Catiana H.; Kikawa, Caroline; Kannan, Shruthi; Davidson, Edgar; Duran, Veronica; Rebellon-Sanchez, David E.; Sanz, Ana M.; Rosso, Fernando; Doranz, Benjamin J.; Einav, Shirit; Matsen, Frederick A.; Goo, Leslie Share Save
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Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics Robinson, Makeda L.; Glass, David R.; Duran, Veronica; Rojas, Olga Lucia Agudelo; Sanz, Ana Maria; Consuegra, Monika; Sahoo, Malaya Kumar; Hartmann, Felix J.; Bosse, Marc; Gelvez, Rosa Margarita; Bueno, Nathalia; Pinsky, Benjamin A.; Montoya, Jose G.; Maecker, Holden; Cardenas, Maria Isabel Estupinan; Centeno, Luis Angel Villar; Garrido, Elsa Marina Rojas; Rosso, Fernando; Bendall, Sean C.; Einav, Shirit Share Save
Synthesis and evaluation of 3-alkynyl-5-aryl-7-aza-indoles as broad-spectrum antiviral agents Martinez-Gualda, Belen; Graus, Mirthe; Camps, Anita; Vanhulle, Emiel; Saul, Sirle; Azari, Siavash; Do Hoang Nhu Tran; Vangeel, Laura; Chiu, Winston; Neyts, Johan; Schols, Dominique; Einav, Shirit; Vermeire, Kurt; De Jonghe, Steven Share Save
Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX Shirasaki, Takayoshi; Feng, Hui; Duyvesteyn, Helen M. E.; Fusco, William G.; McKnight, Kevin L.; Xie, Ling; Boyce, Mark; Kumar, Sathish; Barouch-Bentov, Rina; Gonzalez-Lopez, Olga; McNamara, Ryan; Wang, Li; Hertel-Wulff, Adriana; Chen, Xian; Einav, Shirit; Duncan, Joseph A.; Kapustina, Maryna; Fry, Elizabeth E.; Stuart, David, I; Lemon, Stanley M. Share Save
The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection Schor, Stanford; Pu, Szuyuan; Nicolaescu, Vlad; Azari, Siavash; Koivomagi, Mardo; Karim, Marwah; Cassonnet, Patricia; Saul, Sirle; Neveu, Gregory; Yueh, Andrew; Demeret, Caroline; Skotheim, Jan M.; Jacob, Yves; Randall, Glenn; Einav, Shirit Share Save
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The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection Yao, Zhiyuan; Zanini, Fabio; Kumar, Sathish; Karim, Marwah; Saul, Sirle; Bhalla, Nishank; Panpradist, Nuttada; Muniz, Avery; Narayanan, Aarthi; Quake, Stephen R.; Einav, Shirit Share Save
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