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G

Guangping Gao

university of massachusetts medical school

92H-index
503Paper Count
3.5WCitation Count
Published Papers 234
Publication Date
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Intravenous administration of an engineered AAV9-gene-silencing vector suppresses human SOD1 and extends survival in an ALS mouse model
errNature Communications
IF15.7
err2026-06-25
err0
errOAAI
errFang Wan; Jinchen He; Hong Ma; Debora PiresFerreira; Veena Kumanan; Ji Sun Lee; Xiupeng Chen; Ran He; Qin Su; Thomas L. Gallagher; Sha Zhu; Gabriela Toro Cabrera; Lingzhi Zhao; Joan Shen; Alisha Gruntman; Robert H. Brown; Zuoshang Xu; Guangping Gao; Jun Xie
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errSave
USP24-dependent STAT2 stabilization mediates physiologic and pathologic bone formation
errCell Death & Disease
IF9.6
err2026-05-30
err0
errOAAI
errJung-Min Kim; Yeon-Suk Yang; Jun Xie; Chan Mi Kang; Yeong-Chan Cho; Kwang Hwan Park; Feng Gong; Tadatoshi Sato; Beom-Jik Kim; Guangping Gao; Jae-Hyuck Shim
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errSave
Long-term comparative analysis of AAV9-mediated gene replacement therapies for spinal muscular atrophy in mice
errNature Communications
IF15.7
err2026-05-23
err0
errOAAI
errXiupeng Chen; Qing Xie; Sarah J. Nath; Mojiao Tang; Hong Ma; Yasemin Özgür Günes; Tapan Sharma; Hao Liu; Mengtian Cui; Ailing Du; Mengjia Lu; Sophia Y. Liu; Boonying Wassamon; Mengyao Xu; Joseph Yunxi Wu; Qin Su; Timothy P. Fitzgibbons; Jinghua Liu; Fang Wan; Veena Kumanan; Ran He; Yijie Ma; Jun Yang; Heather L. Gray-Edwards; Thomas L. Gallagher; Phillip W. L. Tai; Guangping Gao; Jun Xie
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errSave
An improved method for high-purity isolation of oligodendrocytes from neonatal and adult mouse brain
erriScience
IF4.1
err2026-05-15
err0
errOAAI
errGuo, Peiyi; Mandon, Elisabet; Wang, Jie; Mooney, Morgan; Reddig, Keith; Vo, Paula; Jerome, Madison C.; Lotun, Anoushka; Spinelli, Jessica B.; Gao, Guangping; Gessler, Dominic J.
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errSave
In vivo adenine base editing ameliorates Dravet syndrome phenotypes in a mouse model
errScience Translational Medicine
IF14.6
err2026-05-13
err0
PREAI
errAndrew T. Nelson; Sophie F. Hill; Matthew Simon; Jérôme Clatot; Holt A. Sakai; Jun Xie; Alexander A. Sousa; Meirui An; Guangping Gao; Cathleen M. Lutz; Ethan M. Goldberg; David R. Liu
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errSave
In vivo base editing rescues liver pathophysiology and peroxisome dysfunction in a mouse model of Zellweger spectrum disorder
errNature Biomedical Engineering
IF26.6
err2026-04-14
err0
errOAAI
errXin D. Gao; Maximiliano Presa; Jordyn E. Duby; Jennifer Ryan; Pierre-Alexandre Piec; Alvin Hsu; Samagya Banskota; Allen Yujie Jiang; Lingxiao Chen; Gregory A. Newby; Erminia Di Pietro; Jonathan M. Levy; Bradford H. Steele; Sarah Lecordier; Fangfei Qin; Ann B. Moser; Jun Xie; Guangping Gao; Nancy E. Braverman; Aamir R. Zuberi; Joseph G. Hacia; Cathleen M. Lutz; David R. Liu
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errSave
Five-year analysis of efficacy and safety ofa bidirectional AAV gene therapy in Tay-Sachs sheep
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-12-01
err0
errOAAI
errTaghian, Toloo; Gallagher, Jillian; Bertrand, Stephanie; Baker, William C.; Mercado, Kalajan Lopez; Benatti, Hector R.; Hall, Erin; Lopez, Yvette; McElroy, Abigail; McCarthy, John T.; Pulaparthi, Sanjana; Fernau, Deborah; Mather, Samuel; Esteves, Sophia; Diffie, Elise; Gross, Amanda; Lahey, Hannah G.; Jiang, Xuntian; Parsley, Elizabeth; Gately, Rachael; Prestigiacomo, Rachel; Johnson, Siauna; Taylor, Amanda; Bierfeldt, Lindsey; Tuominen, Susan; Koehler, Jennifer; Gao, Guangping; Xie, Jun; Su, Qin; King, Robert; Gounis, Matthew J.; Anagnostakou, Vania; Puri, Ajit; Batista, Ana Rita; Sena-Esteves, Miguel; Martin, Douglas R.; Gray-Edwards, Heather
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errSave
Gene therapy delivery of anti-Müllerian hormone in prepubertal female domestic cats induces long-term sterilization
errNature Communications
IF15.7
err2025-11-28
err0
errOAAI
errPhilippe Godin; Nicholas Nagykery; Natalie Sicher; Julie L. Barnes; Amy G. Miller; Christina Bunner; Amy K. Thompson; Motohiro Kano; Guangping Gao; Dan Wang; Patricia K. Donahoe; Linda Rhodes; David A. Brake; Thomas J. Conlon; William F. Swanson; Lindsey M. Vansandt; David Pépin
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errSave
Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies
errNature Communications
IF15.7
err2025-10-07
err0
errOAAI
errSebastian P. Fuchs; Paula G. Mondragon; Rachel Zabizhin; Shallu Tomer; Li Wang; Ethan Cook; Dawn M. Dudley; Kimberly L. Weisgrau; Jessica Furlott; Jennifer Coonen; Eric Alexander; Jun Xie; Guangping Gao; James M. Termini; Jose M. Martinez-Navio; Anjie Zhen; Ronald C. Desrosiers
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errSave
Nature-inspired IL-1 targeted therapy to treat chronic inflammatory diseases
errMolecular Therapy
IF12
err2025-09-10
err0
errOAAI
errYeon-Suk Yang; Mi-Jeong Kim; Sachin Chaugule; Emma Mayer; Ngoc DeSouza; Hong Ma; Jun Xie; Ki-Young Lee; Shaoguang Li; Ellen Gravallese; Guangping Gao; Jae-Hyuck Shim
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errSave
A Compact Base Editor Rescues AATD-associated Liver and Lung Disease in Mouse Models
errMolecular Therapy
IF12
err2025-08-28
err0
errOAAI
errnull Jenny Gao; Nathan Bamidele; Debora Pires-Ferreira; Chunwei Zheng; April Destefano; Haoyang Cheng; Qiushi Tang; Yueying Cao; Jun Xie; Guangping Gao; Alisha Gruntman; Erik Sontheimer; Terence R. Flotte; Wen Xue
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errSave
GFP-on mouse model for interrogation of in vivo gene editing
errNature Communications
IF15.7
err2025-07-31
err0
errOAAI
errCarla Dib; Jack A. Queenan; Leah Swartzrock; Hana Willner; Morgane Denis; Nouraiz Ahmed; Fareha Moulana Zada; Beltran Borges; Carsten T. Charlesworth; Tony Lum; Bradley P. Yates; Caleb Y. Kwon; Augustino V. Scorzo; Scott C. Davis; Jessie R. Davis; Ran He; Jun Xie; Guangping Gao; Tippi C. MacKenzie; David R. Liu; Gregory A. Newby; Agnieszka D. Czechowicz
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errSave
Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life
errNature
IF48.5
err2025-07-30
err0
errOAAI
errAmir Ardeshir; Daniel O’Hagan; Isha Mehta; Siddhartha Shandilya; Lincoln L. J. Hopkins; Lourdes Adamson; Marcelo J. Kuroda; Patricia A. Hahn; Lucas A. B. da Costa; Sebastian P. Fuchs; Jose M. Martinez-Navio; Matthew R. Gardner; Koen K. A. Van Rompay; Diogo M. Magnani; Jeffrey D. Lifson; Guangping Gao; Michael Farzan; Ronald C. Desrosiers; Jishnu Das; Mauricio A. Martins
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errSave
In vivo prime editing rescues alternating hemiplegia of childhood in mice
errCell
IF42.5
err2025-07-21
err0
errOAAI
errAlexander A. Sousa; Markus Terrey; Holt A. Sakai; Christine Q. Simmons; Elena Arystarkhova; Natalia S. Morsci; Laura C. Anderson; Jun Xie; Fabian Suri-Payer; Linda C. Laux; Emmanuel Roze; Sylvie Forlani; Guangping Gao; Simon Frost; Nina Frost; Kathleen J. Sweadner; Alfred L. George; Cathleen M. Lutz; David R. Liu
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errSave
Single-cell transcriptomic analyses provide insights into the tumor microenvironment heterogeneity and invasion phenotype in retinoblastoma
errPATHOLOGY RESEARCH AND PRACTICE
IF3.2
err2025-07-01
err0
PREAI
errZhang, Xiaoliang; Liu, Hong; Lan, Zhida; Gao, Guangping; Li, Guanyu; Dai, Ziwei; Shen, Wei
errShare
errSave
miR-375 protects against acetaminophen-induced acute liver failure by orchestrating pharmacogene expression
errMolecular Therapy
IF12
err2025-06-30
err0
PREAI
errYi Wang; Jinghua Liu; Sha Zhu; Shiliang Hu; Xiupeng Chen; Elisabet Mandon; Ngoc Tam Tran; Songbo Zhang; Yangran Qi; Hong Ma; Ran He; Yu Cao; Qin Su; Thomas L. Gallagher; Zixiu Li; Chan Zhou; Phillip W.L. Tai; Guangping Gao; Jun Xie
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errSave
Adeno-associated Virus-mediated Silencing of Sox4 Leads to Long-Term Amelioration of Liver Phenotypes in Mouse Models of Alagille Syndrome
errGastroenterology
IF25.1
err2025-05-28
err0
PREAI
errDuncan Fox; Jun Xie; Jennifer L. Burwinkel; Josh M. Adams; Kashish Chetal; Marzieh Keivandarian; Yaniv Faingelernt; Sanjay Subramanian; Mario F. Lopez; Anna L. Peters; Nathan Salomonis; Neda Zarrin-Khameh; Guangping Gao; Stacey S. Huppert; Hamed Jafar-Nejad
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errSave
Base editing of trinucleotide repeats that cause Huntington's disease and Friedreich's ataxia reduces somatic repeat expansions in patient cells and in mice
errNATURE GENETICS
IF0
err2025-05-26
err1
errOAAI
errMatuszek, Zaneta; Arbab, Mandana; Kesavan, Maheswaran; Hsu, Alvin; Roy, Jennie C. L.; Zhao, Jing; Yu, Tian; Weisburd, Ben; Newby, Gregory A.; Doherty, Neil J.; Wu, Muzhou; Shibata, Shota; Cristian, Ana; Tao, Y. Allen; Fearnley, Liam G.; Bahlo, Melanie; Rehm, Heidi L.; Xie, Jun; Gao, Guangping; Mouro Pinto, Ricardo; Liu, David R.
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errSave
AAVone: A cost-effective, single-plasmid solution for efficient AAV production with reduced DNA impurities
errMolecular Therapy Nucleic Acids
IF6.1
err2025-05-14
err0
errOAAI
errRongze Yang; Ngoc Tam Tran; Taylor Chen; Mengtian Cui; Yuyan Wang; Tapan Sharma; Yu Liu; Jiantao Zhang; Xinxu Yuan; Danmeng Zhang; Cuiping Chen; Zhen Shi; Lemin Wang; Yuling Dai; Haniya Zaidi; Jiarui Liang; May Chen; Dabbu Jaijyan; Huan Hu; Bing Wang; Cheng Xu; Wenhui Hu; Guangping Gao; Daozhan Yu; Phillip W.L. Tai; Qizhao Wang
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errSave
Lacticaseibacillus paracasei subsp. paracasei Q-1 Exhibits Good Safety and Effectively Prevents Escherichia coli K99-Induced Diarrhea in Mice
errPROBIOTICS AND ANTIMICROBIAL PROTEINS
IF4.4
err2025-04-28
err0
PREAI
errWang, Fengjie; Chen, Li; Li, Yang; Gao, Guangping; Wang, Yanan; Shi, Ruili; Zhang, Hongjun; Chen, Yingyu; Cao, Rui; Shi, Qiumei; Wu, Tonglei
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Róbert Langer
H-index: 262 · Papers: 2.0K
G
Gerald I. Shulman
H-index: 183 · Papers: 819
D
Daniel J. Rader
H-index: 172 · Papers: 1.5K
R
Roger J. Davis
H-index: 166 · Papers: 852
P
Pier Paolo Pandolfi
H-index: 160 · Papers: 818
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