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M

Michael M. Gottesman

national institutes of health

107H-index
698Paper Count
6.5WCitation Count
Published Papers 144
Publication Date
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Cisplatin resistance in an ovarian cancer model is mediated by microtubule dynamics regulator TPPP3 in synergy with tubulin code rewiring
errCell Reports
IF6.9
err2026-06-04
err0
errOAAI
errSachi Horibata; Kishore K. Mahalingan; Ruchi Patel; Yu Fan; Jordan M. Hotz; Adriana Ponton-Almodovar; Keith MacRenaris; Yan Li; Daoud Meerzaman; Michael M. Gottesman; Antonina Roll-Mecak
errShare
errSave
Abcb5-deficient mice show a subtle, pleiotropic phenotype indicating a role for this transporter in intermediary metabolism
erriScience
IF4.1
err2025-09-20
err0
errOAAI
errJean-Pierre Gillet; Louise Gerard; Wilfred Vieira; Marie Fourrez; Florence Gaudray; Birgit Rathkolb; Jan Rozman; Tanja Klein-Rodewald; Lore Becker; Antonio Aguilar-Pimentel; Marion Horsch; Nadine Spielmann; Cornelia Prehn; Benoît Bihin; Johannes Beckers; Helmut Fuchs; Valérie Gailus-Durner; Martin Hrabe de Angelis; Eileen Southon; Lino Tessarollo; Di Xia; Michael M. Gottesman
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errSave
Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib
errISCIENCE
IF4.1
err2025-04-01
err0
errOAAI
errPang, Ying; Li, Qi; Sergi, Zach; Yu, Guangyang; Kim, Olga; Lu, Peng; Chan, Marina; Sang, Xueyu; Wang, Herui; Ranjan, Alice; Robey, Robert W.; Soheilian, Ferri; Tran, Bao; Nunez, Felipe J.; Zhang, Meili; Song, Hua; Zhang, Wei; Davis, Dionne; Gilbert, Mark R.; Gottesman, Michael M.; Liu, Zhenggang; Thomas, Craig J.; Castro, Maria G.; Gujral, Taranjit S.; Wu, Jing
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errSave
Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier (vol 21,27,2024)
errFLUIDS AND BARRIERS OF THE CNS
IF6.2
err2025-01-03
err0
errOAAI
errThomas, Joanna R.; Frye, William J. E.; Robey, Robert W.; Warner, Andrew C.; Butcher, Donna; Matta, Jennifer L.; Morgan, Tamara C.; Edmondson, Elijah F.; Salazar, Paula B.; Ambudkar, Suresh V.; Gottesman, Michael M.
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errSave
Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and Their Zebrafish Homologs at the Blood-Brain Barrier
errMOLECULAR PHARMACOLOGY
IF3
err2024-12-01
err0
PREAI
errQuinlan, John A.; Sabbineni, Sashank; Robey, Robert W.; Lipsey, Crystal C.; Inglut, Collin T.; Thomas, Joanna R.; Walker, Joel R.; Zhou, Wenhui; Huang, Huang-Chiao; Fischell, Michael M. Gottesman
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errSave
TARGETING MITOCHONDRIAL PROTEASE IN DIFFUSE GLIOMAS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errKim, Olga; Sergi, Zach; Yu, Guangyang; Li, Qi; Lu, Peng; Hsia, Ru-Ching; Robey, Robert; Chari, Raj; Wang, Herui; Tran, Bao; Andresson, Thorkell; Gottesman, Michael; Liu, Zhenggang; Graves, Lee; Iwanowicz, Edwin; Wu, Jing
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errSave
Self-Assembled Verteporfin Nanoparticles for Photodynamic and Light-Independent Therapy in Glioblastoma
errADVANCED NANOBIOMED RESEARCH
IF4.4
err2024-09-28
err0
errOAAI
errQuinlan, John A.; Baumiller, Kaylin; Gaur, Anandita; Chiou, Wen-An; Robey, Robert W.; Gottesman, Michael M.; Huang, Huang-Chiao
errShare
errSave
A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in a pancreatic cancer cell line
errSCIENTIFIC REPORTS
IF3.9
err2024-07-10
err0
errOAAI
errMondal, Priya; Alyateem, George; Mitchell, Allison V.; Gottesman, Michael M.
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errSave
Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2024-04-08
err2
errOAAI
errLim, Sanghee; Kwak, Minhye; Kang, Jeonghan; Cesaire, Melissa; Tang, Kayen; Robey, Robert W.; Frye, William J. E.; Karim, Baktiar; Butcher, Donna; Lizak, Martin J.; Dalmage, Mahalia; Foster, Brandon; Nuechterlein, Nicholas; Eberhart, Charles; Cimino, Patrick J.; Gottesman, Michael M.; Jackson, Sadhana
errShare
errSave
Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier
errFLUIDS AND BARRIERS OF THE CNS
IF6.2
err2024-03-15
err2
errOAAI
errThomas, Joanna R.; Frye, William J. E.; Robey, Robert W.; Warner, Andrew C.; Butcher, Donna; Matta, Jennifer L.; Morgan, Tamara C.; Edmondson, Elijah F.; Salazar, Paula B.; Ambudkar, Suresh V.; Gottesman, Michael M.
errShare
errSave
Carrier-Free, Amorphous Verteporfin Nanodrug for Enhanced Photodynamic Cancer Therapy and Brain Drug Delivery
errADVANCED SCIENCE
IF14.1
err2024-03-06
err4
errOAAI
errQuinlan, John A.; Inglut, Collin T.; Srivastava, Payal; Rahman, Idrisa; Stabile, Jillian; Gaitan, Brandon; Del Valle, Carla Arnau; Baumiller, Kaylin; Gaur, Anandita; Chiou, Wen-An; Karim, Baktiar; Connolly, Nina; Robey, Robert W.; Woodworth, Graeme F.; Gottesman, Michael M.; Huang, Huang-Chiao
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errSave
Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-02-01
err4
errOAAI
errGerard, Louise; Duvivier, Laurent; Fourrez, Marie; Salazar, Paula; Sprimont, Lindsay; Xia, Di; Ambudkar, Suresh, V; Gottesman, Michael M.; Gillet, Jean-Pierre
errShare
errSave
Progress in characterizing ABC multidrug transporters in zebrafish
errDRUG RESISTANCE UPDATES
IF21.7
err2024-01-01
err4
PREAI
errThomas, Joanna R.; Frye, William J. E.; Robey, Robert W.; Gottesman, Michael M.
errShare
errSave
The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-12-27
err3
errOAAI
errRobey, Robert W.; Fitzsimmons, Christina M.; Guiblet, Wilfried M.; Frye, William J. E.; Dalmasy, Jose M. Gonzalez; Wang, Li; Russell, Drake A.; Huff, Lyn M.; Perciaccante, Andrew J.; Ali-Rahmani, Fatima; Lipsey, Crystal C.; Wade, Heidi M.; Mitchell, Allison V.; Maligireddy, Siddhardha S.; Terrero, David; Butcher, Donna; Edmondson, Elijah F.; Jenkins, Lisa M.; Nikitina, Tatiana; Zhurkin, Victor B.; Tiwari, Amit K.; Piscopio, Anthony D.; Totah, Rheem A.; Bates, Susan E.; Arda, H. Efsun; Gottesman, Michael M.; Batista, Pedro J.
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errSave
Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency
errNEURO-ONCOLOGY ADVANCES
IF4.1
err2023-08-21
err8
errOAAI
errKim, Olga; Butler, Madison; Sergi, Zach; Robey, Robert W.; Zhang, Meili; Chari, Raj; Pang, Ying; Yu, Guangyang; Zhang, Wei; Song, Hua; Davis, Dionne; Hawley, Robert G.; Wen, Xinyu; Wang, Herui; Quezado, Martha; Tran, Bao; Merchant, Mythili; Ranjan, Alice; Furnari, Frank B.; Khan, Javed; Gilbert, Mark R.; Ryan Miller, Christopher; Gottesman, Michael M.; Pommier, Yves; Wu, Jing
errShare
errSave
IBRUTINIB DISRUPTS BLOOD-TUMOR BARRIER INTEGRITY TO ENHANCE CNS DRUG DELIVERY AND RODENT GLIOMA MODEL SURVIVAL
errNEURO-ONCOLOGY
IF13.4
err2023-06-12
err0
errOAAI
errLim, Sanghee; Kwak, Minhye; Tang, Kayen; Cesaire, Melissa; Robey, Robert; Gottesman, Michael; Jackson, Sadhana
errShare
errSave
Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance
errCANCER GENE THERAPY
IF5
err2023-04-07
err9
errOAAI
errAlyateem, George; Wade, Heidi M.; Bickert, Aaron A.; Lipsey, Crystal C.; Mondal, Priya; Smith, MacKinzie D.; Labib, Rania M.; Mock, Beverly A.; Robey, Robert W.; Gottesman, Michael M.
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errSave
Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter
errSCIENTIFIC REPORTS
IF3.9
err2021-12-17
err17
errOAAI
errRobey, Robert W.; Robinson, Andrea N.; Ali-Rahmani, Fatima; Huff, Lyn M.; Lusvarghi, Sabrina; Vahedi, Shahrooz; Hotz, Jordan M.; Warner, Andrew C.; Butcher, Donna; Matta, Jennifer; Edmondson, Elijah F.; Lee, Tobie D.; Roth, Jacob S.; Lee, Olivia W.; Shen, Min; Tanner, Kandice; Hall, Matthew D.; Ambudkar, Suresh, V; Gottesman, Michael M.
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errSave
Dual Inhibition of Histone Deacetylases and the Mechanistic Target of Rapamycin Promotes Apoptosis in Cell Line Models of Uveal Melanoma
errINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
IF4.7
err2021-09-17
err5
errOAAI
errPatel, Ruchi P.; Thomas, Joanna R.; Curt, Katherine M.; Fitzsimmons, Christina M.; Batista, Pedro J.; Bates, Susan E.; Gottesman, Michael M.; Robey, Robert W.
errShare
errSave
Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-11-09
err36
errOAAI
errSajid, Andaleeb; Lusvarghi, Sabrina; Murakami, Megumi; Chufan, Eduardo E.; Abel, Biebele; Gottesman, Michael M.; Durell, Stewart R.; Ambudkar, Suresh, V
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errSave

Research Directions

No research directions
Co-authors
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John N. Weinstein
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