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Deep Learning-Guided Discovery of Dual Inhibitors of SARS-CoV-2 Entry and 3CL Protease Gao, Peng; Pavlinov, Ivan; Xu, Miao; Chen, Catherine Z.; Morales Vasquez, Desarey; Zhang, Qi; Ye, Yihong; Martinez-Sobrido, Luis; Zheng, Wei; Shen, Min Share Save
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Repurposing of lonafarnib as a treatment for SARS-CoV-2 infection Khan, Mohsin; Irvin, Parker; Park, Seung Bum; Ivester, Hannah M.; Ricardo-Lax, Inna; Leek, Madeleine; Grieshaber, Ailis; Jang, Eun Sun; Coutermarsh-Ott, Sheryl; Zhang, Qi; Maio, Nunziata; Jiang, Jian-Kang; Li, Bing; Huang, Wenwei; Wang, Amy Q.; Xu, Xin; Hu, Zongyi; Zheng, Wei; Ye, Yihong; Rouault, Tracey; Rice, Charles; Allen, Irving C.; Liang, T. Jake Share Save
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Mono-UFMylation promotes misfolding-associated secretion of α-synuclein Wang, Lihui; Xu, Yue; Fukushige, Tetsunari; Saidi, Layla; Wang, Xiaorong; Yu, Clinton; Lee, Jin-Gu; Krause, Michael; Huang, Lan; Ye, Yihong Share Save
J-domain proteins: From molecular mechanisms to diseases Marszalek, Jaroslaw; De Los Rios, Paolo; Cyr, Douglas; Mayer, Matthias P.; Adupa, Vasista; Andreasson, Claes; Blatch, Gregory L.; Braun, Janice E. A.; Brodsky, Jeffrey L.; Bukau, Bernd; Chapple, J. Paul; Conz, Charlotte; Dementin, Sebastien; Genevaux, Pierre; Genest, Olivier; Goloubinoff, Pierre; Gestwicki, Jason; Hammond, Colin M.; Hines, Justin K.; Ishikawa, Koji; Joachimiak, Lukasz A.; Kirstein, Janine; Liberek, Krzysztof; Mokranjac, Dejana; Nillegoda, Nadinath; Ramos, Carlos H. I.; Rebeaud, Mathieu; Ron, David; Rospert, Sabine; Sahi, Chandan; Shalgi, Reut; Tomiczek, Bartlomiej; Ushioda, Ryo; Ustyantseva, Elizaveta; Ye, Yihong; Zylicz, Maciej; Kampinga, Harm H. Share Save
USP19 deubiquitinase inactivation regulates α-synuclein ubiquitination and inhibits accumulation of Lewy body-like aggregates in mice Schorova, Lenka; Bedard, Nathalie; Khayachi, Anouar; Ho, Hung-Hsiang; Bolivar-Pedroso, Joao; Huynh, Julie; Piccirelli, Mikaela; Wang, Yifei; Plourde, Marie; Luo, Wen; del Cid-Pellitero, Esther; Shlaifer, Irina; Castellanos-Montiel, Maria Jose; Yu, Ziqi; Valenzuela, Dulce Valeria Carrillo; Lacalle-Aurioles, Maria; Kriz, Anita; Ye, Yihong; Durcan, Thomas M.; Wing, Simon S. Share Save
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Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes Yan, Wenjing; Zhong, Yongwang; Hu, Xin; Xu, Tuan; Zhang, Yinghua; Kales, Stephen; Qu, Yanyan; Talley, Daniel C. C.; Baljinnyam, Bolormaa; LeClair, Christopher A. A.; Simeonov, Anton; Polster, Brian M. M.; Huang, Ruili; Ye, Yihong; Rai, Ganesha; Henderson, Mark J. J.; Tao, Dingyin; Fang, Shengyun Share Save
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