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M

Michel O. Steinmetz

psi

82H-index
389Paper Count
2.3WCitation Count
Published Papers 157
Publication Date
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Taxane-induced conformational changes in the microtubule lattice activate GEF-H1-dependent RhoA signalling
errNature Cell Biology
IF19.1
err2026-09-24
err0
errOAAI
errJoyce C. M. Meiring; Varsha Mahapatra; Ruijie Liu; Molly S. C. Gravett; Daan Morren; Harriet A. J. Saunders; Sung Ryul Choi; Andressa Pelster José; Adela Karhanova; Ioanna Metallidou; Alex Moore; Marèl F. M. Spoelstra; Ilya S. Grigoriev; Matteo Giono; Saishree S. Iyer; Samantha J. Stehbens; J. Fernando Díaz; Zdenek Lansky; Kelly E. Stecker; Michel O. Steinmetz; Stuart C. Howes; Lukas C. Kapitein; Anna Akhmanova
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An integrated experimental and computational pipeline for crystallographic fragment screening of membrane protein in the lipid cubic phase
errCommunications Chemistry
IF6.2
err2026-05-13
err0
errOAAI
errChia-Ying Huang; Robert Cheng; Alexander Metz; Denis Bucher; Fabio Andres; Arianna Bacchin; Hannah Glover; Christoph P. Sager; Meitian Wang; Michel O. Steinmetz; Michael Hennig; May Sharpe
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errSave
Structural basis of microtubule-mediated signal transduction
errCell
IF42.5
err2025-12-08
err0
errOAAI
errSung Ryul Choi; Thorsten B. Blum; Matteo Giono; Bibhas Roy; Ioannis Vakonakis; Dominic Schmid; Nicole Oelgarth; Apisha Ranganathan; Alvar D. Gossert; G.V. Shivashankar; Alfred Zippelius; Michel O. Steinmetz
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errSave
Asymmetric Total Synthesis of (−)-Glycybridin B, a Pharmacophore Screened Candidate for Tubulin Binding
errChemistry – A European Journal
IF0
err2025-08-06
err0
errOAAI
errDr. Alice Maiocchi; Dr. Maxim Shevelev; Dr. Zlata Boiarska; Dr. Juan Estévez-Gallego; Dr. Francesca Bonato; Dr. Paolo Orlando; Alessandra Chinosi; Emanuele Marcone; Dr. Andrea Citarella; Dr. Dragos Horvath; Prof. Dr. Michel O. Steinmetz; Dr. Andrea E. Prota; Dr. Alexandre Varnek; Dr. Valerio Fasano; Prof. Dr. Daniele Passarella
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errSave
Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap
errNATURE COMMUNICATIONS
IF15.7
err2025-03-10
err0
errOAAI
errEstevez-Gallego, Juan; Blum, Thorsten B.; Ruhnow, Felix; Gili, Maria; Speroni, Silvia; Garcia-Castellanos, Raquel; Steinmetz, Michel O.
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errSave
Centriolar cap proteins CP110 and CPAP control slow elongation of microtubule plus ends
errJOURNAL OF CELL BIOLOGY
IF6.4
err2025-01-23
err0
errOAAI
errIyer, Saishree S.; Chen, Fangrui; Ogunmolu, Funso E.; Moradi, Shoeib; Volkov, Vladimir A.; van Grinsven, Emma J.; van Hoorn, Chris; Wu, Jingchao; Andrea, Nemo; Hua, Shasha; Jiang, Kai; Vakonakis, Ioannis; Potocnjak, Mia; Herzog, Franz; Gigant, Benoit; Gudimchuk, Nikita; Stecker, Kelly E.; Dogterom, Marileen; Steinmetz, Michel O.; Akhmanova, Anna
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errSave
Bridging the maytansine and vinca sites: Cryptophycins target β-tubulin ' s T5-loop
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-06-01
err4
errOAAI
errAbel, Anne-Catherine; Muhlethaler, Tobias; Dessin, Cedric; Schachtsiek, Thomas; Sammet, Benedikt; Sharpe, Timothy; Steinmetz, Michel O.; Sewald, Norbert; Prota, Andrea E.
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Microtubule specialization by plus TIP networks: from mechanisms to functional implications
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2024-04-01
err2
errOAAI
errMeier, Sandro M.; Steinmetz, Michel O.; Barral, Yves
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errSave
The novel microtubule-destabilizing compound AUS_001 maintains unique binding to the colchicine site of tubulin and elicits reversible cellular effects relative to other anti-tubulin agents
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errLelie, Herman; Chou, Yao-Chieh; King, Alastair J.; Boiarska, Zlata; Prota, Andrea E.; Steinmetz, Michel O.; Koutsioumpa, Marina
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errSave
Modular synthesis of functional libraries by accelerated SuFEx click chemistry
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err3
errOAAI
errHomer, Joshua A.; Koelln, Rebecca A.; Barrow, Andrew S.; Gialelis, Timothy L.; Boiarska, Zlata; Steinohrt, Nikita S.; Lee, Erinna F.; Yang, Wen-Hsuan; Johnson, Robert M.; Chung, Taemoon; Habowski, Amber N.; Vishwakarma, Dharmendra S.; Bhunia, Debmalya; Avanzi, Charlotte; Moorhouse, Adam D.; Jackson, Mary; Tuveson, David A.; Lyons, Scott K.; Lukey, Michael J.; Fairlie, W. Douglas; Haider, Shozeb M.; Steinmetz, Michel O.; Prota, Andrea E.; Moses, John E.
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errSave
A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err0
errOAAI
errReynders, Martin; Garscia, Malgorzata; Mueller-Deku, Adrian; Wranik, Maximilian; Krauskopf, Kristina; de la Rosa, Luis de la Osa; Schaffer, Konstantin; Joetten, Anna; Rode, Alexander; Stierle, Valentin; Kraus, Yvonne; Baumgartner, Benedikt; Ali, Ahmed; Bubeneck, Andrei; Seal, Trina; Steinmetz, Michel O.; Paulitschke, Philipp; Thorn-Seshold, Oliver
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errSave
A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers
errNATURE COMMUNICATIONS
IF15.7
err2023-12-02
err2
errOAAI
errWranik, Maximilian; Kepa, Michal W.; Beale, Emma V.; James, Daniel; Bertrand, Quentin; Weinert, Tobias; Furrer, Antonia; Glover, Hannah; Gashi, Dardan; Carrillo, Melissa; Kondo, Yasushi; Stipp, Robin T.; Khusainov, Georgii; Nass, Karol; Ozerov, Dmitry; Cirelli, Claudio; Johnson, Philip J. M.; Dworkowski, Florian; Beale, John H.; Stubbs, Scott; Zamofing, Thierry; Schneider, Marco; Krauskopf, Kristina; Gao, Li; Thorn-Seshold, Oliver; Bostedt, Christoph; Bacellar, Camila; Steinmetz, Michel O.; Milne, Christopher; Standfuss, Jorg
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errSave
The motor domain of the kinesin Kip2 promotes microtubule polymerization at microtubule tips
errJOURNAL OF CELL BIOLOGY
IF6.4
err2023-04-24
err2
errOAAI
errChen, Xiuzhen; Portran, Didier; Widmer, Lukas A. A.; Stangier, Marcel M. M.; Czub, Mateusz P. P.; Liakopoulos, Dimitris; Stelling, Jorg; Steinmetz, Michel O. O.; Barral, Yves
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errSave
Structural insight into the stabilization of microtubules by taxanes
errELIFE
IF0
err2023-03-06
err23
errOAAI
errProta, Andrea E.; Lucena-Agell, Daniel; Ma, Yuntao; Estevez-Gallego, Juan; Li, Shuo; Bargsten, Katja; Josa-Prado, Fernando; Altmann, Karl-Heinz; Gaillard, Natacha; Kamimura, Shinji; Muhlethaler, Tobias; Gago, Federico; Oliva, Maria A.; Steinmetz, Michel O.; Fang, Wei-Shuo; Diaz, J. Fernando
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errSave
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography
errNATURE COMMUNICATIONS
IF15.7
err2023-02-17
err16
errOAAI
errWranik, Maximilian; Weinert, Tobias; Slavov, Chavdar; Masini, Tiziana; Furrer, Antonia; Gaillard, Natacha; Gioia, Dario; Ferrarotti, Marco; James, Daniel; Glover, Hannah; Carrillo, Melissa; Kekilli, Demet; Stipp, Robin; Skopintsev, Petr; Brunle, Steffen; Muhlethaler, Tobias; Beale, John; Gashi, Dardan; Nass, Karol; Ozerov, Dmitry; Johnson, Philip J. M.; Cirelli, Claudio; Bacellar, Camila; Braun, Markus; Wang, Meitian; Dworkowski, Florian; Milne, Chris; Cavalli, Andrea; Wachtveitl, Josef; Steinmetz, Michel O. O.; Standfuss, Jorg
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errSave
Multivalency ensures persistence of a plus TIP body at specialized microtubule ends
errNATURE CELL BIOLOGY
IF19.1
err2022-12-19
err22
errOAAI
errMeier, Sandro M.; Farcas, Ana-Maria; Kumar, Anil; Ijavi, Mahdiye; Bill, Robert T.; Stelling, Joerg; Dufresne, Eric R.; Steinmetz, Michel O.; Barral, Yves
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errSave
VASH1-SVBP and VASH2-SVBP generate different detyrosination profiles on microtubules
errJOURNAL OF CELL BIOLOGY
IF6.4
err2022-12-13
err10
errOAAI
errRamirez-Rios, Sacnicte; Choi, Sung Ryul; Sanyal, Chadni; Blum, Thorsten B. B.; Bosc, Christophe; Krichen, Fatma; Denarier, Eric; Soleilhac, Jean-Marc; Blot, Beatrice; Janke, Carsten; Stoppin-Mellet, Virginie; Magiera, Maria M. M.; Arnal, Isabelle; Steinmetz, Michel O. O.; Moutin, Marie-Jo
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Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts
errELIFE
IF0
err2022-12-12
err8
errOAAI
errGuyomar, Charlotte; Bousquet, Clement; Ku, Siou; Heumann, John M.; Guilloux, Gabriel; Gaillard, Natacha; Heichette, Claire; Duchesne, Laurence; Steinmetz, Michel O.; Gibeaux, Romain; Chretien, Denis; Welburn, Julie P., I
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Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-12-01
err33
PREAI
errBarreca, Marilia; Span, Virginia; Rocca, Roberta; Bivacqua, Roberta; Abel, Anne -Catherine; Maruca, Annalisa; Montalbano, Alessandra; Raimondi, Maria Valeria; Tarantelli, Chiara; Gaudio, Eugenio; Cascione, Luciano; Rinaldi, Andrea; Bai, Ruoli; Steinmetz, Michel O.; Prota, Andrea E.; Alcaro, Stefano; Hamel, Ernest; Bertoni, Francesco; Barraja, Paola
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Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-11-01
err19
errOAAI
errde la Roche, Noelia Montel; Muehlethaler, Tobias; Di Martino, Rita Maria Concetta; Ortega, Jose Antonio; Gioia, Dario; Roy, Bibhas; Prota, Andrea E.; Steinmetz, Michel O.; Cavalli, Andrea
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Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
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