Mark A. Lemmon - Publications, H-index & Citations

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Mark A. Lemmon

yale university

87H-index

335Paper Count

3.4WCitation Count

Published Papers 109

Publication Date

Lipids regulate epidermal growth factor receptor activation by its ligands

Biochemical Society Transactions

IF4.3

2026-01-01

OAAI

Hutchison, James M.; Lemmon, Mark A.

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The role of kinase domain dimerization in EGFR activation

Structure

IF4.3

2025-12-19

PREAI

Zaritza O. Petrova; Long Han; Yuko Tsutsui; Joshua B. Sheetz; Kumar D. Ashtekar; Mark A. Lemmon

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Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling

ELIFE

IF0

2024-07-19

OAAI

Muehlenbeck, Henning; Tsutsui, Yuko; Lemmon, Mark A.; Bender, Kyle W.; Zipfel, Cyril

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Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes

CELL REPORTS

IF6.9

2024-01-01

OAAI

Mudumbi, Krishna C.; Burns, Eric A.; Schodt, David J.; Petrova, Zaritza O.; Kiyatkin, Anatoly; Kim, Lucy W.; Mangiacapre, Emma M.; Ortiz-Caraveo, Irais; Ortiz, Hector Rivera; Hu, Chun; Ashtekar, Kumar D.; Lidke, Keith A.; Lidke, Diane S.; Lemmon, Mark A.

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Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE

NATURE COMMUNICATIONS

IF15.7

2023-10-04

OAAI

Chongsaritsinsuk, Joann; Steigmeyer, Alexandra D.; Mahoney, Keira E.; Rosenfeld, Mia A.; Lucas, Taryn M.; Smith, Courtney M.; Li, Alice; Ince, Deniz; Kearns, Fiona L.; Battison, Alexandria S.; Hollenhorst, Marie A.; Shon, D. Judy; Tiemeyer, Katherine H.; Attah, Victor; Kwon, Catherine; Bertozzi, Carolyn R.; Ferracane, Michael J.; Lemmon, Mark A.; Amaro, Rommie E.; Malaker, Stacy A.

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Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma

NATURE COMMUNICATIONS

IF15.7

2023-05-05

OAAI

Berko, Esther R.; Witek, Gabriela M.; Matkar, Smita; Petrova, Zaritza O.; Wu, Megan A.; Smith, Courtney M.; Daniels, Alex; Kalna, Joshua; Kennedy, Annie; Gostuski, Ivan; Casey, Colleen; Krytska, Kateryna; Gerelus, Mark; Pavlick, Dean; Ghazarian, Susan; Park, Julie R.; Marachelian, Araz; Maris, John M.; Goldsmith, Kelly C.; Radhakrishnan, Ravi; Lemmon, Mark A.; Mosse, Yael P.

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Essential role for Rac in heregulin β1 mitogenic signaling:: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Yang, CF; Liu, Y; Lemmon, MA; Kazanietz, MG

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Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

298

OAAI

Dawson, JP; Berger, MB; Lin, CC; Schlessinger, J; Lemmon, MA; Ferguson, KM

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Efficacy of Osimertinib in Patients with Lung Cancer Positive for Uncommon EGFR Exon 19 Deletion Mutations

CLINICAL CANCER RESEARCH

IF10.2

2023-03-13

OAAI

Grant, Michael J.; V. Aredo, Jacqueline; Starrett, Jacqueline H.; Stockhammer, Paul; van Rosenburgh, Iris K. van Alderwerelt; Wurtz, Anna; Piper-Valillo, Andrew J.; Piotrowska, Zofia; Falcon, Christina; Yu, Helena A.; Aggarwal, Charu; Scholes, Dylan; Patil, Tejas; Nguyen, Christina; Phadke, Manali; Li, Fang -Yong; Neal, Joel; Lemmon, Mark A.; Walther, Zenta; Politi, Katerina; Goldberg, Sarah B.

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Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations

NATURE COMMUNICATIONS

IF15.7

2022-11-10

OAAI

van Rosenburgh, Iris K. van Alderwerelt; Lu, David M.; Grant, Michael J.; Stayrook, Steven E.; Phadke, Manali; Walther, Zenta; Goldberg, Sarah B.; Politi, Katerina; Lemmon, Mark A.; Ashtekar, Kumar D.; Tsutsui, Yuko

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Looking lively: emerging principles of pseudokinase signaling

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2022-10-01

OAAI

Sheetz, Joshua B.; Lemmon, Mark A.

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ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

CELL REPORTS

IF6.9

2021-10-01

OAAI

Shi, Fumin; Mendrola, Jeannine M.; Sheetz, Joshua B.; Wu, Neo; Sommer, Anselm; Speer, Kelsey F.; Noordermeer, Jasprina N.; Kan, Zhong-Yuan; Perry, Kay; Englander, S. Walter; Stayrook, Steven E.; Fradkin, Lee G.; Lemmon, Mark A.

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Phosphatidylserine binding directly regulates TIM-3 function

BIOCHEMICAL JOURNAL

IF4.3

2021-09-14

OAAI

Smith, Courtney M.; Li, Alice; Krishnamurthy, Nithya; Lemmon, Mark A.

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EComputational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-04

OAAI

Patil, Keshav; Jordan, Earl Joseph; Park, Jin H.; Suresh, Krishna; Smith, Courtney M.; Lemmon, Abigail A.; Mosse, Yael P.; Lemmon, Mark A.; Radhakrishnan, Ravi

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Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB

BIOCHEMICAL JOURNAL

IF4.3

2020-10-29

OAAI

Artim, Stephen C.; Kiyatkin, Anatoly; Lemmon, Mark A.

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Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics

SCIENCE SIGNALING

IF6.6

2020-08-18

OAAI

Kiyatkin, Anatoly; van Rosenburgh, Iris K. van Alderwerelt; Klein, Daryl E.; Lemmon, Mark A.

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Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases

MOLECULAR CELL

IF16.6

2020-08-01

OAAI

Sheetz, Joshua B.; Mathea, Sebastian; Karvonen, Hanna; Malhotra, Ketan; Chatterjee, Deep; Niininen, Wilhelmiina; Perttila, Robert; Preuss, Franziska; Suresh, Krishna; Stayrook, Steven E.; Tsutsui, Yuko; Radhakrishnan, Ravi; Ungureanu, Daniela; Knapp, Stefan; Lemmon, Mark A.

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Drug Sensitivity and Allele Specificity of First-Line Osimertinib Resistance EGFR Mutations

CANCER RESEARCH

IF16.6

2020-05-15

OAAI

Starrett, Jacqueline H.; Guernet, Alexis A.; Cuomo, Maria Emanuela; Poels, Kamrine E.; van Rosenburgh, Iris K. van Alderwerelt; Nagelberg, Amy; Farnsworth, Dylan; Price, Kristin S.; Khan, Hina; Ashtekar, Kumar Dilip; Gaefele, Mmaserame; Ayeni, Deborah; Stewart, Tyler F.; Kuhlmann, Alexandra; Kaech, Susan M.; Unni, Arun M.; Homer, Robert; Lockwood, William W.; Michor, Franziska; Goldberg, Sarah B.; Lemmon, Mark A.; Smith, Paul D.; Cross, Darren A. E.; Politi, Katerina

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Drug Sensitivity and Allele-specificity of First-line Osimertinib Resistance EGFR Mutations

FASEB JOURNAL

IF4.2

2020-04-20

PREAI

Starrett, Jacqueline; Guernet, Alexis; Cuomo, Maria; Poels, Kamrine; van Rosenburgh, Iris; Nagelberg, Amy; Farnsworth, Dylan; Price, Kristin; Khan, Hina; Ashtekar, Kumar; Gaefele, Mmaserame; Ayeni, Deborah; Stewart, Tyler; Kuhlmann, Alexandra; Kaech, Susan; Unni, Arun; Homer, Robert; Lockwood, William; Michor, Franziska; Goldberg, Sarah; Lemmon, Mark; Smith, Paul; Cross, Darren; Politi, Katerina

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Neuregulin Signaling Is a Mechanism of Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma

MOLECULAR CANCER THERAPEUTICS

IF5.5

2019-11-01

OAAI

Baro, Marta; Lopez Sambrooks, Cecilia; Burtness, Barbara A.; Lemmon, Mark A.; Contessa, Joseph N.

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Research Directions