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The Specification and Functional Maturation of Sub-Cerebral Projection Neurons Derived from Human Induced Pluripotent Stem Cells Jordan, Zachary; Singh, Anukriti; Kattapong-Graber, Seth; Goswami, Sonal; Sanjana, Neville E.; Zuccaro, Emanuela; Zhang, Feng; Eggan, Kevin; Hsieh, Jenny; Hermann, Brian P.; Hebert, Jean M.; Maroof, Asif Mirza Share Save
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Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells Liang, Wen-Wei; Muller, Simon; Hart, Sydney K.; Wessels, Hans-Hermann; Mendez-Mancilla, Alejandro; Sookdeo, Akash; Choi, Olivia; Caragine, Christina M.; Corman, Alba; Lu, Lu; Kolumba, Olena; Williams, Breanna; Sanjana, Neville E. Share Save
Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling Yan, Rachel E.; Corman, Alba; Katgara, Lyla; Wang, Xiao; Xue, Xinhe; Gajic, Zoran Z.; Sam, Richard; Farid, Michael; Friedman, Samuel M.; Choo, Jungwook; Raimondi, Ivan; Ganesan, Shridar; Katsevich, Eugene; Greenfield, Jeffrey P.; Dahmane, Nadia; Sanjana, Neville E. Share Save
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes Megagiannis, Platon; Mei, Yuan; Yan, Rachel E.; Yuan, Lin; Wilde, Jonathan J.; Eckersberg, Hailey; Suresh, Rahul; Tan, Xinzhu; Chen, Hong; Farmer, W. Todd; Cha, Kuwook; Le, Phuong Uyen; Catoire, Helene; Rochefort, Daniel; Kwan, Tony; Yee, Brian A.; Dion, Patrick; Krishnaswamy, Arjun; Cloutier, Jean-Francois; Stifani, Stefano; Petrecca, Kevin; Yeo, Gene W.; Murai, Keith K.; Feng, Guoping; Rouleau, Guy A.; Ideker, Trey; Sanjana, Neville E.; Zhou, Yang Share Save
Genome- wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase Ferrarone, John R.; Thomas, Jerin; Unni, Arun M.; Zheng, Yuxiang; Nagiec, Michal J.; Gardner, Eric E.; Mashadova, Oksana; Li, Kate; Koundouros, Nikos; Montalbano, Antonino; Mustafa, Meer; Cantley, Lewis C.; Blenis, John; Sanjana, Neville E.; Varmus, Harold Share Save
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Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction Shi, Xi; Lu, Congyi; Corman, Alba; Nikish, Alexandra; Zhou, Yang; Platt, Randy J.; Iossifov, Ivan; Zhang, Feng; Pan, Jen Q.; Sanjana, Neville E. Share Save
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Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq Wessels, Hans-Hermann; Mendez-Mancilla, Alejandro; Hao, Yuhan; Papalexi, Efthymia; Mauck, William M.; Lu, Lu; Morris, John A.; Mimitou, Eleni P.; Smibert, Peter; Sanjana, Neville E.; Satija, Rahul Share Save
Expanding the Scope of Bacterial CRISPR Activation with PAM- Flexible dCas9 Variants Kiattisewee, Cholpisit; Karanjia, Ava, V; Legut, Mateusz; Daniloski, Zharko; Koplik, Samantha E.; Nelson, Joely; Kleinstiver, Benjamin P.; Sanjana, Neville E.; Carothers, James M.; Zalatan, Jesse G. Share Save
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Cancer genes disfavoring T cell immunity identified via integrated systems approach Kishton, Rigel J.; Patel, Shashank J.; Decker, Amy E.; Vodnala, Suman K.; Cam, Maggie; Yamamoto, Tori N.; Patel, Yogin; Sukumar, Madhusudhanan; Yu, Zhiya; Ji, Michelle; Henning, Amanda N.; Gurusamy, Devikala; Palmer, Douglas C.; Stefanescu, Roxana A.; Girvin, Andrew T.; Lo, Winifred; Pasetto, Anna; Malekzadeh, Parisa; Deniger, Drew C.; Wood, Kris C.; Sanjana, Neville E.; Restifo, Nicholas P. Share Save
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The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes Garipler, Gorkem; Lu, Congyi; Morrissey, Alexis; Lopez-Zepeda, Lorena S.; Pei, Yingzhen; Vidal, Simon E.; Fiore, Ana Paula Zen Petisco; Aydin, Begum; Stadtfeld, Matthias; Ohler, Uwe; Mahony, Shaun; Sanjana, Neville E.; Mazzoni, Esteban O. Share Save
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