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Increasing intracellular dNTP levels improves prime editing efficiency Liu, Pengpeng; Ponnienselvan, Karthikeyan; Nyalile, Thomas; Oikemus, Sarah; Joynt, Anya T.; Iyer, Sukanya; Kelly, Karen; Guo, Dongsheng; Kyawe, Pyae P.; Vanderleeden, Emma; Redick, Sambra D.; Huang, Lei; Chen, Zexiang; Lee, Jeong Min; Schiffer, Celia A.; Harlan, David M.; Wang, Jennifer P.; Emerson Jr, Charles P.; Lawson, Nathan D.; Watts, Jonathan K.; Sontheimer, Erik J.; Luban, Jeremy; Wolfe, Scot A. Share Save
Modular vector assembly enables rapid assessment of emerging CRISPR technologies McGee, Abby, V; Liu, Yanjing, V; Griffith, Audrey L.; Szegletes, Zsofia M.; Wen, Bronte; Kraus, Carolyn; Miller, Nathan W.; Steger, Ryan J.; Velasco, Berta Escude; Bosch, Justin A.; Zirin, Jonathan D.; Viswanatha, Raghuvir; Sontheimer, Erik J.; Goodale, Amy; Greene, Matthew A.; Green, Thomas M.; Doench, John G. Share Save
Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope Bamidele, Nathan; Zhang, Han; Dong, Xiaolong; Cheng, Haoyang; Gaston, Nicholas; Feinzig, Hailey; Cao, Hanbing; Kelly, Karen; Watts, Jonathan K.; Xie, Jun; Gao, Guangping; Sontheimer, Erik J. Share Save
A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors Chen, Zexiang; Kwan, Suet-Yan; Mir, Aamir; Hazeltine, Max; Shin, Minwook; Liang, Shun-Qing; Chan, Io Long; Kelly, Karen; Ghanta, Krishna S.; Gaston, Nicholas; Cao, Yueying; Xie, Jun; Gao, Guangping; Xue, Wen; Sontheimer, Erik J.; Watts, Jonathan K. Share Save
Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo Zhang, Han; Kelly, Karen; Lee, Jonathan; Echeverria, Dimas; Cooper, David; Panwala, Rebecca; Amrani, Nadia; Chen, Zexiang; Gaston, Nicholas; Wagh, Atish; Newby, Gregory A.; Xie, Jun; Liu, David R.; Gao, Guangping; Wolfe, Scot A.; Khvorova, Anastasia; Watts, Jonathan K.; Sontheimer, Erik J. Share Save
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes Adler, Benjamin A.; Trinidad, Marena, I; Bellieny-Rabelo, Daniel; Zhang, Elaine; Karp, Hannah M.; Skopintsev, Petr; Thornton, Brittney W.; Weissman, Rachel F.; Yoon, Peter H.; Chen, Linxing; Hessler, Tomas; Eggers, Amy R.; Colognori, David; Boger, Ron; Doherty, Erin E.; Tsuchida, Connor A.; Tran, Ryan, V; Hofman, Laura; Shi, Honglue; Wasko, Kevin M.; Zhou, Zehan; Xia, Chenglong; Al-Shimary, Muntathar J.; Patel, Jaymin R.; Thomas, Vienna C. J. X.; Pattali, Rithu; Kan, Matthew J.; Vardapetyan, Anna; Yang, Alana; Lahiri, Arushi; Maxwell, Michaela F.; Murdock, Andrew G.; Ramit, Glenn C.; Henderson, Hope R.; Calvert, Roland W.; Bamert, Rebecca S.; Knott, Gavin J.; Lapinaite, Audrone; Pausch, Patrick; Cofsky, Joshua C.; Sontheimer, Erik J.; Wiedenheft, Blake; Fineran, Peter C.; Brouns, Stan J. J.; Sashital, Dipali G.; Thomas, Brian C.; Brown, Christopher T.; Goltsman, Daniela S. A.; Barrangou, Rodolphe; Siksnys, Virginius; Banfield, Jillian F.; Savage, David F.; Doudna, Jennifer A. Share Save
PAM-flexible genome editing with an engineered chimeric Cas9 Zhao, Lin; Koseki, Sabrina R. T.; Silverstein, Rachel A.; Amrani, Nadia; Peng, Christina; Kramme, Christian; Savic, Natasha; Pacesa, Martin; Rodriguez, Tomas C.; Stan, Teodora; Tysinger, Emma; Hong, Lauren; Yudistyra, Vivian; Ponnapati, Manvitha R.; Jacobson, Joseph M.; Church, George M.; Jakimo, Noah; Truant, Ray; Jinek, Martin; Kleinstiver, Benjamin P.; Sontheimer, Erik J.; Chatterjee, Pranam Share Save
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Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag Liang, Shun-Qing; Liu, Pengpeng; Ponnienselvan, Karthikeyan; Suresh, Sneha; Chen, Zexiang; Kramme, Christian; Chatterjee, Pranam; Zhu, Lihua Julie; Sontheimer, Erik J.; Xue, Wen; Wolfe, Scot A. Share Save
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro Meijboom, Katharina E.; Abdallah, Abbas; Fordham, Nicholas P.; Nagase, Hiroko; Rodriguez, Tomas; Kraus, Carolyn; Gendron, Tania F.; Krishnan, Gopinath; Esanov, Rustam; Andrade, Nadja S.; Rybin, Matthew J.; Ramic, Melina; Stephens, Zachary D.; Edraki, Alireza; Blackwood, Meghan T.; Kahriman, Aydan; Henninger, Nils; Kocher, Jean-Pierre A.; Benatar, Michael; Brodsky, Michael H.; Petrucelli, Leonard; Gao, Fen-Biao; Sontheimer, Erik J.; Brown, Robert H.; Zeier, Zane; Mueller, Christian Share Save
Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors Iyer, Sukanya; Mir, Aamir; Vega-Badillo, Joel; Roscoe, Benjamin P.; Ibraheim, Raed; Zhu, Lihua Julie; Lee, Jooyoung; Liu, Pengpeng; Luk, Kevin; Mintzer, Esther; Guo, Dongsheng; Soares de Brito, Josias; Emerson Jr, Charles P.; Zamore, Phillip D.; Sontheimer, Erik J.; Wolfe, Scot A. Share Save
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Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts Shin, Minwook; Chan, Io Long; Cao, Yuming; Gruntman, Alisha M.; Lee, Jonathan; Sousa, Jacquelyn; Rodriguez, Tomas C.; Echeverria, Dimas; Devi, Gitali; Debacker, Alexandre J.; Moazami, Michael P.; Krishnamurthy, Pranathi Meda; Rembetsy-Brown, Julia M.; Kelly, Karen; Yukselen, Onur; Donnard, Elisa; Parsons, Teagan J.; Khvorova, Anastasia; Sontheimer, Erik J.; Maehr, Rene; Garber, Manuel; Watts, Jonathan K. Share Save
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Genome-wide detection of CRISPR editing in vivo using GUIDE-tag Liang, Shun-Qing; Liu, Pengpeng; Smith, Jordan L.; Mintzer, Esther; Maitland, Stacy; Dong, Xiaolong; Yang, Qiyuan; Lee, Jonathan; Haynes, Cole M.; Zhu, Lihua Julie; Watts, Jonathan K.; Sontheimer, Erik J.; Wolfe, Scot A.; Xue, Wen Share Save
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