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张璋 cover

张璋 (Zhang Zhang)

beijing key laboratory of agricultural genetic resources and biotechnology

76H-index
642Paper Count
3.4WCitation Count
Published Papers 220
Publication Date
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Assembly and comparative analysis of the complete mitochondrial genome of a orchid cultivar ‘Jingzi’ reveals multichromosomal architecture and plastid-derived DNA transfers
errBMC Plant Biology
IF4.8
err2026-07-22
err0
errOAAI
errBoyang Zhang; Jiuyang Tang; Hailong Wang; Bo Wang; Zhang Zhang; Guiming Liu; Yunfu Li; Jianhua Wei; Jiewei Zhang
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Targeting SARS-CoV-2 Mpro and PLpro by Repurposing Clinically Approved Drugs
errViruses
IF3.5
err2026-03-03
err0
errOAAI
errQiaoyu Fang; Meng Lu; Derong Chen; Liangxu Xie; Wenxu Hong; Zhang Zhang; Xuqiao Hu
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Transformer-based Deep Learning Models with Shape Guidance for Predicting Breast Cancer in Mammography Images
errJournal of Imaging Informatics in Medicine
IF0
err2025-12-19
err0
errOAAI
errKengo Takahashi; Yuwen Zeng; Zhang Zhang; Kei Ichiji; Takuma Usuzaki; Ryusei Inamori; Haoyang Liu; Noriyasu Homma
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Paragenetic Sequence of Li-Minerals in the 509 Daobanxi Lithium Pegmatite Deposit, Northwestern China: Implications for Lithium Mineralization in LCT-Type Pegmatites
errJournal of Earth Science
IF4.7
err2025-12-10
err0
PREAI
errTao Hong; Zeli Jiang; Yongbao Gao; Zhang Zhang; Mingguo Zhai; Xingwang Xu; Jun Gao
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Ultrasound-assisted one-step extraction of safflower red and yellow pigments by natural ternary deep eutectic solvents: Extraction optimization and mechanism, separation and biological activities of pigments
errFood Chemistry
IF9.8
err2025-12-02
err0
PREAI
errXimei Zhang; Zhang Zhang; Bo Zhao; Xinyu Yang; Yixin Zhang; Yuping Tang; Shijun Yue
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High-level soluble expression of human aldehyde dehydrogenase 2 in Escherichia coli achieved through lactose-mediated induction optimization
errProtein Expression and Purification
IF1.2
err2025-12-01
err0
PREAI
errLi, Hongxia; Wang, Xiong; Wang, Xinye; Zhang, Zhang; Ran, Linmin
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ANALYSIS OF THE IMPACT OF PAIN CARE COMBINED WITH PSYCHOLOGICAL COUNSELING ON THE REHABILITATION QUALITY OF PATIENTS AFTER VASCULAR SURGERY INTERVENTION
errSCHIZOPHRENIA BULLETIN
IF4.8
err2025-12-01
err0
PREAI
errZhang, Yan; Xiong, Lan; Zhang, Zhang; Da, Xiuwei
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Mapping cellular interactions and communication landscapes in cervical cancer via single-cell transcriptomics
errDiscover Oncology
IF2.9
err2025-11-25
err0
errOAAI
errShaoli Zhuang; Xiaoxiao Deng; Furong Fu; Zhang Zhang
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ClinMAVE: a curated database for clinical application of data from multiplexed assays of variant effect
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-11-01
err0
PREAI
errMa, Chenyu; Li, Zhao; Tang, Xin; Li, Pan; Li, Li; Wang, Shiting; Wu, Jiayu; Luo, Liheng; Liu, Yaping; Zhang, Zhang; Wang, Xiaoyue
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Charting the expression landscape of human long non-coding RNAs across diverse biological contexts with LncExpDB 2.0
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-11-01
err0
errOAAI
errQi, Yue; Li, Zhao; Zhou, Xinyu; Wang, Miaomiao; Zhang, Zhang; Ma, Lina
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errSave
EWAS Open Platform 2026: a deeply integrated resource for epigenome-wide association studies
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-11-01
err0
PREAI
errYang, Fei; Xiong, Zhuang; Zong, Wenting; Kong, Demian; Tang, Bixia; Chen, Xupeng; Wei, Yaoke; Yu, Xiangyu; Zhang, Yiran; Zou, Dong; Zhang, Zhang; Bao, Yiming; Li, Rujiao
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Cancer-associated fibroblast-derived GAS6 increases resistance to chemotherapy through AXL/STAT3/ABCG1 in gastric cancer
errBritish Journal of Cancer
IF6.8
err2025-10-28
err0
PREAI
errTae Hoon Kim; Dagyeong Lee; Hye Jeong Oh; In-Hye Ham; Tuyen Thanh Tran; Yulim Lee; Tae-Min Kim; Rolf A. Brekken; Zhang Zhang; Ding Ke; Hoon Hur
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errSave
Case report: Adolescent breast hypertrophy with a tendency toward phyllodes tumor formation: first reported case in China
errFrontiers in Oncology
IF3.3
err2025-10-15
err0
errOAAI
errRuiheng Liao; Yang Xiao; Yujing Chang; Zhang Zhang; Yange Zhang
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Fluorination Engineering for Stable Interfacial Chemistry in Deep Eutectic Amide-Based Electrolytes Enables High-Performance LiNi0.8Co0.1Mn0.1O2/Li Batteries
errENERGY & ENVIRONMENTAL MATERIALS
IF14.1
err2025-09-10
err0
errOAAI
errYuanxin Gao; Xinyi Wang; Dong Lv; Zhang Zhang; Jiangpeng Li; Xiaoyan Feng; Jingchao Chai; Yun Zheng; Yu Peng; Yanqing Wang; Yingying Wang; Lingyu Zhu; Zhihong Liu
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errSave
M4MLF-YOLO: A Lightweight Semantic Segmentation Framework for Spacecraft Component Recognition
errRemote Sensing 2025, Vol. 17, Page 3144
IF0
err2025-09-10
err0
errOAAI
errWenxin Yi; Zhang Zhang; Liang Chang
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errSave
A multi-tissue single-cell expression atlas in cattle
errNature Genetics
IF0
err2025-09-05
err0
errOAAI
errBo Han; Houcheng Li; Weijie Zheng; Qi Zhang; Ao Chen; Senlin Zhu; Tao Shi; Fei Wang; Dong Zou; Yu Song; Wen Ye; Aixia Du; Yihan Fu; Minghui Jia; Zhonghao Bai; Zhixiang Yuan; Wansheng Liu; Wenbin Tuo; Jayne C. Hope; David E. MacHugh; John F. O’Grady; Ole Madsen; Goutam Sahana; Yonglun Luo; Lin Lin; Congjun Li; Zexi Cai; Bingjie Li; Jinming Huang; Lin Liu; Zhang Zhang; Zhu Ma; Yali Hou; George E. Liu; Yu Jiang; Hui-zeng Sun; Lingzhao Fang; Dongxiao Sun
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errSave
Embedding city revival into state-driven innovation system: unravelling the state-local entrepreneurial toolkits for innovation
errCAMBRIDGE JOURNAL OF REGIONS ECONOMY AND SOCIETY
IF4.7
err2025-09-01
err1
PREAI
errLi, Ziming; Zhao, Yiqing; Zhang, Zhang
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errSave
Nonuniform Doppler extraction-enhanced multichannel extensive cancellation algorithm for passive radar using Iridium satellite signals
errScientific Reports
IF3.9
err2025-08-13
err0
errOAAI
errHongwei Fu; Zhang Zhang; Yu Luo; Tingting Fu; Jianglin Li; Xin Jian; Hao Cha
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errSave
Pose acquisition of non-cooperative spacecraft by point cloud template matching
errADVANCES IN SPACE RESEARCH
IF2.8
err2025-05-01
err0
errOAAI
errFeng, JQ; Zhang, Z; Yang, ZG; Yu, JP; Chen, W; Chang, L; Chen, HY
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errSave
Tailoring High-Elasticity Cross-Linked Polymer Electrolytes to Harmonize Flexible Solid-State Lithium-Oxygen Batteries
errADVANCED FUNCTIONAL MATERIALS
IF19
err2025-04-21
err0
PREAI
errLi, ZZ; Wu, J; Li, MH; Huang, DL; Pan, KC; Dou, YY; Wang, J; Zhang, Z; Zhou, Z
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errSave

Research Directions

1. 生物信息及高通量测序方法2. RNA修饰新方法的建立和调控机制3. 宏基因组数据挖掘和合成生物学招聘信息：实验室研究兴趣广泛，鼓励创新，欢迎对科学研究有着强烈兴趣的同学加入。对新入学研究生无背景要求，鼓励学科交叉。同时招聘博士后等青年科研人员，希望具有分子遗传/化学生物/合成生物学，或生物信息学/系统生物学/计算机背景，对方法学创新感兴趣，有探索新方向的志向和能力。个人经历2022 – 今 中山大学生命科学学院 副教授2020 – 2022 中山大学生命科学学院 副研究员2017 – 2020 中山大学生命科学学院 博士后 (合作导师：骆观正教授)2012 – 2017 中山大学生命科学学院 生物化学与分子生物学 理学博士 (导师：施苏华教授)2008 – 2012 中山大学海洋学院 海洋生物资源与环境 理学学士讲授课程生命起源与进化（主讲，2023）生命科学研讨课（参与，2022）表观遗传学前沿（参与，2022）学术成就长期以来从事表观转录组学研究，在RNA修饰新方法的建立、基因表达调控和进化分析等方面具有丰富的经验。目前主要从事RNA相关修饰检测方法的开发，及N6甲基腺嘌呤(m6A)修饰的机制与功能研究。成果发表于Nature Methods, Science Advances, National Science Review等期刊，并申请多项发明专利。主要学术成果1. 开发出具有单碱基精度m6A测序新方法m6A-REF-seq，引用超过150次 (Sci. Adv., 2019Methods, 2021)。2. 构建体外无修饰RNA文库，系统性地评估和矫正RNA修饰检测方法 (Nat. Methods, 2021)。承担课题主持国家自然科学基金面上项目 (2023-2026)国家自然科学基金 "青年科学基金项目" (2022-2024)广东省基础与应用基础研究基金项目 "区域联合基金-青年基金项目" (2020-2022)中国博士后科学基金 "面上项目" (2019-2020) 已结题高校基本科研业务费 "青年教师培育项目" 主持 (2019-2021) 已结题参与国家自然科学基金 "面上项目" (2019-2022)国家重点研发计划-合成生物学青年项目(2022-2027)国家重点研发计划“前言生物技术”重点专项 (2022-2027)论文专著代表作1. Zhang, Z.#, Chen, T.#, Chen, H.X., Xie, Y.Y., Chen, L.Q., Zhao, Y.L., Liu, B.D., ..., and Luo, G.Z.*(2021). Systematic calibration of epitranscriptomic maps using a synthetic modification-free RNA library. Nat. Methods 18, 1213–1222.2. Zhang, Z., Chen, L.Q., Zhao, Y.L., Yang, C.G., Roundtree, I.A., Zhang, Z., Ren, J., Xie, W., He, C., and Luo, G.Z.* (2019). Single-base mapping of m6A by an antibody-independent method. Sci. Adv. 5, eaax0250.3. Zhong, Z.D.#, Xie, Y.Y.#, Chen, H.X., Lan, Y.L., Liu, X.H., Ji, J.Y., Wu, F., Jin, L., Chen, J., Mak, DW, Zhang, Z.*, Luo, G.Z.*(2023). Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing. Nat. Communications. 14, 19064. Chen, L.Q., Zhang, Z., Chen, H.X., Xi, J.F., Liu, X.H., Ma, D.Z., Zhong, Y.H., ..., and Luo, G.Z.* (2022). High-precision mapping reveals rare N6-deoxyadenosine methylation in the mammalian genome. Cell Discov. 8, 1–11.5. He, Z.#, Xu, S.#, Zhang, Z.#, Guo, W., Lyu, H., Zhong, C., Boufford, D.E., Duke, N.C., and Shi, S.* (2020). Convergent adaptation of the genomes of woody plants at the land-sea interface. Natl. Sci. Rev. 7, 978–993.6. Chen, H.X., Zhang, Z., Ma, D. Z., Chen, L.Q., and Luo, G.Z.* (2021). Mapping single-nucleotide m6A by m6A-REF-seq. Methods. 10.1016/j.ymeth.2021.06.0137. Chen, T., Li, Y., Ma, D.Z., Zhang, Z., Xi, J.F., and Luo, G.Z.* (2021). Establishment of transposase-assisted low-input m6A sequencing technique. J. Genet. Genomics 48, 8–11.8. Xu, S.#, He, Z.#, Zhang, Z.#, Guo, Z., Guo, W., Lyu, H., Li, J., Yang, M., Du, Z., Huang, Y., et al. (2017). The origin, diversification and adaptation of a major mangrove clade (Rhizophoreae) revealed by whole-genome sequencing. Natl. Sci. Rev. 4, 721–734.9. Xu, S.#, He, Z.#, Guo, Z., Zhang, Z., Wyckoff, G.J., Greenberg, A., Wu, C.I., and Shi, S.*. (2017). Genome-wide convergence during evolution of mangroves from woody plants. Mol. Biol. Evol. 34, 1008–1015.专利1. 骆观正陈涛谢应源张璋陈鸿萱刘标地. 一种混样检测 RNA 修饰并实现精准定量的方法. 发明专利. 专利号：ZL202110844695.1 已授权2. 骆观正李言马冬曌奚剑飞. 一种采用Tn5转座酶辅助构建微量样品m6A修饰检测文库的方法及其应用. 发明专利. 专利号：ZL202110314939.5 已授权3. 骆观正张璋. 一种合成无修饰RNA文库及用来校准RNA修饰检测的方法. 发明专利. 专利号：ZL202011230780.0 已授权4. 骆观正陈丽倩陈鸿萱. 一种具有单碱基分辨率的核酸修饰检测方法. 发明专利. 专利号：ZL202011034485 .8 已授权
Co-authors
Cooperation Journals
P
Peter F. Stadler
H-index: 119 · Papers: 1.3K
张洋 cover
张洋 (Yang Zhang)
H-index: 112 · Papers: 1.6K
H
Heng Li
H-index: 98 · Papers: 585
J
Jo Vandesompele
H-index: 96 · Papers: 803
李
李霞 (Xia Li)
H-index: 92 · Papers: 1.3K
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