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STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma Prutsch, Nicole; He, Shuning; Berezovskaya, Alla; Durbin, Adam D.; Dharia, Neekesh V.; Maher, Kelsey A.; Matthews, Jamie D.; Hare, Lucy; Turner, Suzanne D.; Stegmaier, Kimberly; Kenner, Lukas; Merkel, Olaf; Look, A. Thomas; Abraham, Brian J.; Zimmerman, Mark W. Share Save
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Emi1 Maintains Genomic Integrity during Zebrafish Embryogenesis and Cooperates with p53 in Tumor Suppression Rhodes, Jennifer; Amsterdam, Adam; Sanda, Takaomi; Moreau, Lisa A.; McKenna, Keith; Heinrichs, Stefan; Ganem, Neil J.; Ho, Karen W.; Neuberg, Donna S.; Johnston, Adam; Ahn, Yebin; Kutok, Jeffery L.; Hromas, Robert; Wray, Justin; Lee, Charles; Murphy, Carly; Radtke, Ina; Downing, James R.; Fleming, Mark D.; MacConaill, Laura E.; Amatruda, James F.; Gutierrez, Alejandro; Galinsky, Ilene; Stone, Richard M.; Ross, Eric A.; Pellman, David S.; Kanki, John P.; Look, A. Thomas Share Save
A Zebrafish Model of Myelodysplastic Syndrome Produced through tet2 Genomic Editing Gjini, Evisa; Mansour, Marc R.; Sander, Jeffry D.; Moritz, Nadine; Nguyen, Ashley T.; Kesarsing, Michiel; Gans, Emma; He, Shuning; Chen, Si; Ko, Myunggon; Kuang, You-Yi; Yang, Song; Zhou, Yi; Rodig, Scott; Zon, Leonard I.; Joung, J. Keith; Rao, Anjana; Look, A. Thomas Share Save
p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition Oppel, Felix; Shao, Senyao; Gendreizig, Sarah; Zimmerman, Mark W.; Schurmann, Matthias; Flavian, Viyof Ful; Goon, Peter; Chi, Susan N.; Aster, Jon C.; Sudhoff, Holger; Look, A. Thomas Share Save
EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma Durbin, Adam D.; Wang, Tingjian; Wimalasena, Virangika K.; Zimmerman, Mark W.; Li, Deyao; Dharia, Neekesh, V; Mariani, Luca; Shendy, Noha A. M.; Nance, Stephanie; Patel, Anand G.; Shao, Ying; Mundada, Maya; Maxham, Lily; Park, Paul M. C.; Sigua, Logan H.; Morita, Ken; Conway, Amy Saur; Robichaud, Amanda L.; Perez-Atayde, Antonio R.; Bikowitz, Melissa J.; Quinn, Taylor R.; Wiest, Olaf; Easton, John; Schonbrunn, Ernst; Bulyk, Martha L.; Abraham, Brian J.; Stegmaier, Kimberly; Look, A. Thomas; Qi, Jun Share Save
Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL Akahane, Koshi; Kimura, Shunsuke; Miyake, Kunio; Watanabe, Atsushi; Kagami, Keiko; Yoshimura, Kentaro; Shinohara, Tamao; Harama, Daisuke; Kasai, Shin; Goi, Kumiko; Kawai, Tomoko; Hata, Kenichiro; Kiyokawa, Nobutaka; Koh, Katsuyoshi; Imamura, Toshihiko; Horibe, Keizo; Look, A. Thomas; Minegishi, Masayoshi; Sugita, Kanji; Takita, Junko; Inukai, Takeshi Share Save
Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma Zimmerman, Mark W.; Durbin, Adam D.; He, Shuning; Oppel, Felix; Shi, Hui; Tao, Ting; Li, Zhaodong; Berezovskaya, Alla; Liu, Yu; Zhang, Jinghui; Young, Richard A.; Abraham, Brian J.; Look, A. Thomas Share Save
Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma Liang, Huan-Chang; Costanza, Mariantonia; Prutsch, Nicole; Zimmerman, Mark W.; Gurnhofer, Elisabeth; Montes-Mojarro, Ivonne A.; Abraham, Brian J.; Prokoph, Nina; Stoiber, Stefan; Tangermann, Simone; Lobello, Cosimo; Oppelt, Jan; Anagnostopoulos, Ioannis; Hielscher, Thomas; Pervez, Shahid; Klapper, Wolfram; Zammarchi, Francesca; Silva, Daniel-Adriano; Garcia, K. Christopher; Baker, David; Janz, Martin; Schleussner, Nikolai; Fend, Falko; Pospisilova, Sarka; Janikova, Andrea; Wallwitz, Jacqueline; Stoiber, Dagmar; Simonitsch-Klupp, Ingrid; Cerroni, Lorenzo; Pileri, Stefano; de Leval, Laurence; Sibon, David; Fataccioli, Virginie; Gaulard, Philippe; Assaf, Chalid; Knorr, Fabian; Damm-Welk, Christine; Woessmann, Wilhelm; Turner, Suzanne D.; Look, A. Thomas; Mathas, Stephan; Kenner, Lukas; Merkel, Olaf Share Save
Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss He, Shuning; Zimmerman, Mark W.; Layden, Hillary M.; Berezovskaya, Alla; Etchin, Julia; Martel, Megan W.; Thurston, Grace; Jing, Chang-Bin; van Rooijen, Ellen; Kaufman, Charles K.; Rodig, Scott J.; Zon, Leonard I.; Patton, E. Elizabeth; Mansour, Marc R.; Look, A. Thomas Share Save
Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma Anderson, Nicole M.; Qin, Xiaodan; Finan, Jennifer M.; Lam, Andrew; Athoe, Jacob; Missiaen, Rindert; Skuli, Nicolas; Kennedy, Annie; Saini, Amandeep S.; Tao, Ting; Zhu, Shizhen; Nissim, Itzhak; Look, A. Thomas; Qing, Guoliang; Simon, M. Celeste; Feng, Hui Share Save
Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) Shaw, Timothy I.; Dong, Li; Tian, Liqing; Qian, Chenxi; Liu, Yu; Ju, Bensheng; High, Anthony; Kavdia, Kanisha; Pagala, Vishwajeeth R.; Shaner, Bridget; Pei, Deqing; Easton, John; Janke, Laura J.; Porter, Shaina N.; Ma, Xiaotu; Cheng, Cheng; Pruett-Miller, Shondra M.; Choi, John; Yu, Jiyang; Peng, Junmin; Gu, Wei; Look, A. Thomas; Downing, James R.; Zhang, Jinghui Share Save
GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma Dong, Zhiwei; Yeo, Kok Siong; Lopez, Gonzalo; Zhang, Cheng; Eggum, Erin N. Dankert; Rokita, Jo Lynne; Ung, Choong Yong; Levee, Taylor M.; Her, Zuag Paj; Howe, Cassie J.; Hou, Xiaonan; van Ree, Janine H.; Li, Shuai; He, Shuning; Tao, Ting; Fritchie, Karen; Torres-Mora, Jorge; Lehman, Julia S.; Meves, Alexander; Razidlo, Gina L.; Rathi, Komal S.; Weroha, S. John; Look, A. Thomas; van Deursen, Jan M.; Li, Hu; Westendorf, Jennifer J.; Maris, John M.; Zhu, Shizhen Share Save
Targeting cancer cells with potent activators of the PP2A protein phosphatase tumor suppressor Morita, Ken; He, Shuning; Nowak, Radoslaw P.; Wang, Jinhua; Zimmerman, Mark W.; Fu, Cong; Durbin, Adam D.; Gray, Nathanael S.; Fischer, Eric S.; Look, A. Thomas Share Save
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