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C

Charles O. Rock

University of Tennessee Health Science Center

92H-index
365Paper Count
2.6WCitation Count
Published Papers 145
Publication Date
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Cryo-EM reconstruction of oleate hydratase bound to a phospholipid membrane bilayer
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2024-09-01
err5
errOAAI
errOldham, Michael L.; Qayyum, M. Zuhaib; Kalathur, Ravi C.; Rock, Charles O.; Radka, Christopher D.
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Development of Brain Penetrant Pyridazine Pantothenate Kinase Activators
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-13
err0
errOAAI
errTangallapally, Rajendra; Subramanian, Chitra; Yun, Mi-Kyung; Edwards, Anne; Sharma, Lalit Kumar; Yang, Lei; Creed, Katie; Wang, Jina; Jackowski, Suzanne; Rock, Charles O.; White, Stephen W.; Lee, Richard E.
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errSave
Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis
errJOURNAL OF STRUCTURAL BIOLOGY
IF5.1
err2024-03-01
err1
errOAAI
errRadka, Christopher D.; Rock, Charles O.
errShare
errSave
Staphylococcus aureus oleate hydratase produces ligands that activate PPARalpha
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errRadka, Christopher; Rosch, Jason; Rock, Charles
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errSave
The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-02-01
err7
errOAAI
errRadka, Christopher D.; Grace, Christy R.; Hasdemir, Hale S.; Li, Yupeng; Rodriguez, Carlos C.; Rodrigues, Patrick; Oldham, Michael L.; Qayyum, M. Zuhaib; Pitre, Aaron; MacCain, William J.; Kalathur, Ravi C.; Tajkhorshid, Emad; Rock, Charles O.
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errSave
Pantothenate Kinase Activation Restores Brain Coenzyme A in a Mouse Model of Pantothenate Kinase-Associated Neurodegeneration
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2024-01-01
err4
errOAAI
errSubramanian, Chitra; Frank, Matthew W.; Sukhun, Rajaa; Henry, Christopher E.; Wade, Anna; Harden, Mallory E.; Rao, Satish; Tangallapally, Rajendra; Yun, Mi-Kyung; White, Stephen W.; Lee, Richard E.; Sinha, Uma; Rock, Charles O.; Jackowski, Suzanne
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Lysophosphatidylglycerol (LPG) phospholipase D maintains membrane homeostasis in Staphylococcus aureus by converting LPG to lysophosphatidic acid
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-07-01
err4
errOAAI
errSubramanian, Chitra; Yun, Mi-Kyung; Frank, Matthew M.; Rock, Charles O.
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errSave
Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-05-01
err11
errOAAI
errBishop, Timothy R.; Subramanian, Chitra; Bilotta, Eric M.; Garnar-Wortzel, Leopold; Ramos, Anissa R.; Zhang, Yuxiang; Asiaban, Joshua N.; Ott, Christopher J.; Rock, Charles O.; Erb, Michael A.
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errSave
The Phospholipase A1 Activity of Glycerol Ester Hydrolase (Geh) Is Responsible for Extracellular 2-12(S)-Methyltetradecanoyl-Lysophosphatidylglycerol Production in Staphylococcus aureus
errMSPHERE
IF3.1
err2023-04-20
err3
errOAAI
errSubramanian, Chitra; Frank, Matthew W.; Yun, My-Kyung; Rock, Charles O.
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errSave
A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-04-01
err8
errOAAI
errWhaley, Sarah G.; Frank, Matthew W.; Rock, Charles O.
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errSave
Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err33
errOAAI
errDavis, JN; Rock, CO; Cheng, MG; Watson, JB; Ashmun, RA; Kirk, H; Kay, RJ; Roussel, MF
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errSave
The carboxy terminus of oleate hydratase forms a membrane anchor that permits fatty acid acquisition from membranes
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errRadka, Christopher; Grace, Christy; Oldham, Michael; Tajkhorshid, Emad; Rock, Charles
errShare
errSave
A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errWhaley, Sarah; Frank, Matthew; Rock, Charles
errShare
errSave
Mining Fatty Acid Biosynthesis for New Antimicrobials
errANNUAL REVIEW OF MICROBIOLOGY
IF9.9
err2022-09-08
err15
errOAAI
errRadka, Christopher D.; Rock, Charles O.
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errSave
Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-08-01
err10
errOAAI
errRadka, Christopher D.; Miller, Darcie J.; Frank, Matthew W.; Rock, Charles O.
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errSave
A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance
errNATURE COMMUNICATIONS
IF15.7
err2022-06-07
err20
errOAAI
errLeshchiner, Dmitry; Rosconi, Federico; Sundaresh, Bharathi; Rudmann, Emily; Ramirez, Luisa Maria Nieto; Nishimoto, Andrew T.; Wood, Stephen J.; Jana, Bimal; Bujan, Noemi; Li, Kaicheng; Gao, Jianmin; Frank, Matthew; Reeve, Stephanie M.; Lee, Richard E.; Rock, Charles O.; Rosch, Jason W.; van Opijnen, Tim
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errSave
Domain architecture and catalysis of the Staphylococcus aureus fatty acid kinase
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-06-01
err10
errOAAI
errSubramanian, Chitra; Cuypers, Maxime G.; Radka, Christopher D.; White, Stephen W.; Rock, Charles O.
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errSave
Amino Acid Metabolism Controls Fatty Acid Structure in Staphylococcus aureus
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errWhaley, Sarah G.; Frank, Matthew W.; Rock, Charles O.
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errSave
Structure of cysteate acyltransferase, the condensation enzyme that initiates sulfonolipid biosynthesis by inhabitants of the gut microbiome
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errRadka, Christopher; Rock, Charles
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errSave
Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-03-01
err9
errOAAI
errGullett, Jessica M.; Cuypers, Maxime G.; Grace, Christy R.; Pant, Shashank; Subramanian, Chitra; Tajkhorshid, Emad; Rock, Charles O.; White, Stephen W.
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errSave

Research Directions

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Co-authors
Cooperation Journals
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Frank J. Gonzalez
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Jon Clardy
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T
Tom Curran
H-index: 120 · Papers: 458
T
Thomas A. Wynn
H-index: 114 · Papers: 373
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