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The TetR-like regulator Sco4385 and Crp-like regulator Sco3571 modulate heterologous production of antibiotics in Streptomyces coelicolor M512 Wilcken, Sarah; Koutsandrea, Panagiota-Hanna; Bakker, Tomke; Kulik, Andreas; Orthwein, Tim; Franz-Wachtel, Mirita; Harbig, Theresa; Nieselt, Kay Katja; Forchhammer, Karl; Broetz-Oesterhelt, Heike; Macek, Boris; Mordhorst, Silja; Kaysser, Leonard; Gust, Bertolt Share Save
Salamandamide Lipodipeptides Are Biosynthetic Intermediate Shunt Products of the Nonamodular Nonribosomal Peptide Assembly Lines of the Viscosin Family Bhattarai, Keshab; Majer, Thomas; Haussmann, Manuela; Schollmeyer, Dieter; Kramer, Markus; Oni, Feyisara Eyiwumi; Hoefte, Monica; Voget, Rabea; Guetschow, Michael; Ruetalo, Natalia; Schindler, Michael; Straetener, Jan; Wannenwetsch, Tatjana; Broetz-Oesterhelt, Heike; Karongo, Ryan; Masberg, Benedikt; Laemmerhofer, Michael; Hennessy, Rosanna Catherine; Muletz-Wolz, Carly R.; Gross, Harald Share Save
Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets Deschner, Felix; Mostert, Dietrich; Daniel, Jan-Martin; Voltz, Alexander; Schneider, Dana Carina; Khangholi, Navid; Bartel, Jueurorgen; de Carvalho, Lais Pessanha; Brauer, Madita; Gorelik, Tatiana E.; Kleeberg, Christian; Risch, Timo; Haeckl, F. P. Jake; Benitez, Laura Herraiz; Andreas, Anastasia; Kany, Andreas Martin; Jezequel, Gwenaelle; Hofer, Walter; Muesken, Mathias; Held, Jana; Bischoff, Markus; Seemann, Ralf; Broetz-Oesterhelt, Heike; Schneider, Tanja; Sieber, Stephan; Mueller, Rolf; Herrmann, Jennifer Share Save
Conjugation of Polycationic Peptides Extends the Efficacy Spectrum of β-Lactam Antibiotics Werner, Julia; Umstaetter, Florian; Boehmann, Manuel B.; Mueller, Hannah; Beijer, Barbro; Hertlein, Tobias; Kaschnitz, Laura; Bram, Veronika; Kleist, Christian; Klika, Karel D.; Muehlberg, Eric; Braune, Gabriel; Wohlfart, Sabrina; Gaertner, Martin; Peter, Silke; Zimmermann, Stefan; Haberkorn, Uwe; Ohlsen, Knut; Broetz-Oesterhelt, Heike; Mier, Walter; Uhl, Philipp Share Save
Ticagrelor alters the membrane of Staphylococcus aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance Leeten, Kirsten; Jacques, Nicolas; Esquembre, Lidia Alejo; Schneider, Dana C.; Straetener, Jan; Henriksen, Camilla; Musumeci, Lucia; Putters, Florence; Melo, Sofia; Sanchez-Lopez, Elena; Giera, Martin; Penoy, Noemie; Piel, Geraldine; Verlaine, Olivier; Amoroso, Ana; Joris, Bernard; Slavetinsky, Christoph J.; Goffin, Eric; Pirotte, Bernard; Frees, Dorte; Broetz-Oesterhelt, Heike; Lancellotti, Patrizio; Oury, Cecile Share Save
The microbiome-derived antibacterial lugdunin acts as a cation ionophore in synergy with host peptides Berscheid, Anne; Straetener, Jan; Schilling, Nadine A.; Ruppelt, Dominik; Konnerth, Martin C.; Schittek, Birgit; Krismer, Bernhard; Peschel, Andreas; Steinem, Claudia; Grond, Stephanie; Broetz-Oesterhelt, Heike Share Save
The Dual Mode of Antibacterial Action of the Synthetic Small Molecule DCAP Involves Lipid II Binding Ludwig, Kevin C.; Puls, Jan-Samuel; de Opitz, Cruz L. Matos; Innocenti, Paolo; Daniel, Jan-Martin; Bornikoel, Jan; Arts, Melina; Krannich, Sebastian; Straetener, Jan; Brajtenbach, Dominik; Henrichfreise, Beate; Sass, Peter; Mueller, Anna; Martin, Nathaniel I.; Brotz-Oesterhelt, Heike; Kubitscheck, Ulrich; Grein, Fabian; Schneider, Tanja Share Save
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Antibacterial Marinopyrroles and Pseudilins Act as Protonophores Castro-Falcon, Gabriel; Straetener, Jan; Bornikoel, Jan; Reimer, Daniela; Purdy, Trevor N.; Berscheid, Anne; Schempp, Florence M.; Liu, Dennis Y.; Linington, Roger G.; Broetz-Oesterhelt, Heike; Hughes, Chambers C. Share Save
Fosfomycin Uptake in Escherichia coli Is Mediated by the Outer-Membrane Porins OmpF, OmpC, and LamB Bianchi, Martina; Winterhalter, Mathias; Harbig, Theresa Anisja; Hoeroempoeli, Daniel; Ghai, Ishan; Nieselt, Kay; Broetz-Oesterhelt, Heike; Mayer, Christoph; Borisova-Mayer, Marina Share Save
Unnatural Endotype B PPAPs as Novel Compounds with Activity against Mycobacterium tuberculosis Peslalz, Philipp; Grieshober, Mark; Kraus, Frank; Bleisch, Anton; Izzo, Flavia; Lichtenstein, Dajana; Hammer, Helen; Vorbach, Andreas; Momoi, Kyoko; Zanger, Ulrich M.; Broetz-Oesterhelt, Heike; Braeuning, Albert; Plietker, Bernd; Stenger, Steffen Share Save
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Bioinformatics-guided discovery of biaryl-linked lasso peptides Saad, Hamada; Majer, Thomas; Bhattarai, Keshab; Lampe, Sarah; Nguyen, Dinh T.; Kramer, Markus; Straetener, Jan; Broetz-Oesterhelt, Heike; Mitchell, Douglas A.; Gross, Harald Share Save
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