Not logged in CoREST complex inhibition alters RNA splicing to promote neoantigen expression and enhance tumor immunity Fisher, Robert J.; Park, Kihyun; Lee, Kwangwoon; Pinjusic, Katarina; Vanasse, Allison; Ennis, Christina S.; Farokh, Parisa; Ficaro, Scott B.; Marto, Jarrod A.; Jiang, Hanjie; Nam, Eunju; Stransky, Stephanie; Duke-Cohan, Joseph; Akinci, Melis A.; Geethadevi, Anupa; Raabe, Eric; Fiszbein, Ana; Demehri, Shadmehr; Sidoli, Simone; Hicks, Chad W.; Keskin, Derin B.; Wu, Catherine J.; Cole, Philip A.; Alani, Rhoda M. Share Save
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Leveraging relaxation-optimized 1H-13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins Boeszoermenyi, Andras; Radeva, Denitsa L.; Schindler, Sebastian; Valadares, Veronica; Padmanabha Das, Krishna M.; Dubey, Abhinav; Viennet, Thibault; Schmitt, Max; Kast, Peter; Gelev, Vladimir M.; Stoyanov, Nikolay; Burdzhiev, Nikola; Petrov, Ognyan; Ficarro, Scott; Marto, Jarred; Geffken, Ezekiel A.; Dhe-Paganon, Sirano; Seo, Hyuk-Soo; Alexander, Nathan D.; Cooley, Richard B.; Mehl, Ryan A.; Kovacs, Helena; Anklin, Clemens; Bermel, Wolfgang; Kuprov, Ilya; Takeuchi, Koh; Arthanari, Haribabu Share Save
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A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation Ali, Raja H.; Orellana, Esteban A.; Lee, Su Hyun; Chae, Yun-Cheol; Chen, Yantao; Clauwaert, Jim; Kennedy, Alyssa L.; Gutierrez, Ashley E.; Papke, David J.; Valenzuela, Mateo; Silverman, Brianna; Falzetta, Amanda; Ficarro, Scott B.; Marto, Jarrod A.; Fletcher, Christopher D. M.; Perez-Atayde, Antonio; Alcindor, Thierry; Shimamura, Akiko; Prensner, John R.; Gregory, Richard I.; Gutierrez, Alejandro Share Save
Open-source electrophilic fragment screening platform to identify chemical starting points for UCHL1 covalent inhibitors Ficarro, Scott B.; Marto, Zachary H.; Girardi, Nicholas M.; Deng, Dingyu; Maisonet, Isabella Jaen; Adelmant, Guillaume; Fleming, Laura E.; Sharafi, Mona; Tavares, Isidoro; Zhao, Andrew; Kim, Hyojeon; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Buhrlage, Sara J. Share Save
Template-assisted covalent modification underlies activity of covalent molecular glues Li, Yen-Der; Ma, Michelle W.; Hassan, Muhammad Murtaza; Hunkeler, Moritz; Teng, Mingxing; Puvar, Kedar; Rutter, Justine C.; Lumpkin, Ryan J.; Sandoval, Brittany; Jin, Cyrus Y.; Schmoker, Anna M.; Ficarro, Scott B.; Cheong, Hakyung; Metivier, Rebecca J.; Wang, Michelle Y.; Xu, Shawn; Byun, Woong Sub; Groendyke, Brian J.; You, Inchul; Sigua, Logan H.; Tavares, Isidoro; Zou, Charles; Tsai, Jonathan M.; Park, Paul M. C.; Yoon, Hojong; Majewski, Felix C.; Sperling, Haniya T.; Marto, Jarrod A.; Qi, Jun; Nowak, Radoslaw P.; Donovan, Katherine A.; Slabicki, Mikolaj; Gray, Nathanael S.; Fischer, Eric S.; Ebert, Benjamin L. Share Save
APIR: Aggregating Universal Proteomics Database Search Algorithms for Peptide Identification with FDR Control Chen, Yiling Elaine; Ge, Xinzhou; Woyshner, Kyla; McDermott, Meilu; Manousopoulou, Antigoni; Ficarro, Scott B.; Marto, Jarrod A.; Li, Kexin; Wang, Leo David; Li, Jingyi Jessica Share Save
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Epitope editing enables targeted immunotherapy of acute myeloid leukemia Casirati, Gabriele; Cosentino, Andrea; Mucci, Adele; Mahmoud, Mohammed S.; Zabala, Iratxe Ugarte; Zeng, Jing; Ficarro, Scott B.; Klatt, Denise; Brendel, Christian; Rambaldi, Alessandro; Ritz, Jerome; Marto, Jarrod A.; Pellin, Danilo; Bauer, Daniel E.; Armstrong, Scott A.; Genovese, Pietro Share Save
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Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality Li, Zhengnian; Jiang, Jie; Ficarro, Scott B.; Beyett, Tyler S.; To, Ciric; Tavares, Isidoro; Zhu, Yingde; Li, Jiaqi; Eck, Michael J.; Janne, Pasi A.; Marto, Jarrod A.; Zhang, Tinghu; Che, Jianwei; Gray, Nathanael S. Share Save
ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases Li, Zhengnian; Lu, Wenchao; Beyett, Tyler S.; Ficarro, Scott B.; Jiang, Jie; Tse, Jason; Kim, Audrey Yong-Ju; Marto, Jarrod A.; Che, Jianwei; Janne, Pasi A.; Eck, Michael J.; Zhang, Tinghu; Gray, Nathanael S. Share Save
The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells (vol 21, pg 572, 2015) Zhu, Di; Wang, Zhongqiu; Zhao, Jian-Jun; Calimeri, Teresa; Meng, Jiang; Hideshima, Teru; Fulciniti, Mariateresa; Kang, Yue; Ficarro, Scott B.; Tai, Yu-Tzu; Hunter, Zachary; Mcmilin, Douglas; Tong, Haoxuan; Mitsiades, Constantine S.; Wu, Catherine J.; Treon, Steven P.; Dorfman, David M.; Pinkus, Geraldine; Munshi, Nikhil C.; Tassone, Pierfrancesco; Marto, Jarrod A.; Anderson, Kenneth C.; Carrasco, Ruben D. Share Save
A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex Chen, Han; Lye, Ming F.; Gorgulla, Christoph; Ficarro, Scott B.; Cuny, Gregory D.; Scott, David A.; Wu, Fan; Rothlauf, Paul W.; Wang, Xiaoou; Fernandez, Rosio; Pesola, Jean M.; Draga, Sorin; Marto, Jarrod A.; Hogle, James M.; Arthanari, Haribabu; Coen, Donald M. Share Save
Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange Cruite, Justin T.; Nowak, Radoslaw P.; Donovan, Katherine A.; Ficarro, Scott B.; Huang, Huang; Liu, Hu; Liu, Yingpeng; Marto, Jarrod A.; Metivier, Rebecca J.; Fischer, Eric S.; Jones, Lyn H. Share Save
Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders Li, Yen-Der; Ma, Michelle W.; Hassan, Muhammad Murtaza; Puvar, Kedar; Teng, Mingxing; Sandoval, Brittany; Lumpkin, Ryan; Ficarro, Scott B.; Wang, Michelle Y.; Xu, Shawn; Groendyke, Brian J.; Sigua, Logan H.; Tavares, Isidoro; Zou, Charles; Tsai, Jonathan M.; Park, Paul M.; Yoon, Hojong; Nowak, Radoslaw P.; Marto, Jarrod A.; Qi, Jun; Donovan, Katherine A.; Slabicki, Mikolaj; Gray, Nathanael S.; Fischer, Eric S.; Ebert, Benjamin L. Share Save
Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors Lu, Wenchao; Fan, Mengyang; Ji, Wenzhi; Tse, Jason; You, Inchul; Ficarro, Scott B.; Tavares, Isidoro; Che, Jianwei; Kim, Audrey Y.; Zhu, Xijun; Boghossian, Andrew; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Hinshaw, Stephen M.; Nabet, Behnam; Corsello, Steven M.; Kwiatkowski, Nicholas; Marto, Jarrod A.; Zhang, Tinghu; Gray, Nathanael S. Share Save
Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1 Lu, Wenchao; Liu, Yao; Gao, Yang; Geng, Qixiang; Gurbani, Deepak; Li, Lianbo; Ficarro, Scott B.; Meyer, Cynthia J.; Sinha, Dhiraj; You, Inchul; Tse, Jason; He, Zhixiang; Ji, Wenzhi; Che, Jianwei; Kim, Audrey Y.; Yu, Tengteng; Wen, Kenneth; Anderson, Kenneth C.; Marto, Jarrod A.; Westover, Kenneth D.; Zhang, Tinghu; Gray, Nathanael S. Share Save
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