logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
M

Michael Gotthardt

Max Delbruck Center for Molecular Medicine in the Helmholtz Association

46H-index
146Paper Count
1.1WCitation Count
Published Papers 91
Publication Date
logo
Targeting intracellular cholesterol imbalance rescues sarcomere–ER contact site signaling and ER remodeling in dilated cardiomyopathy
errSignal Transduction and Targeted Therapy
IF52.7
err2026-06-17
err0
errOAAI
errNadezda Ignatyeva; Cleophas Cheruiyot; Hafiza Nosheen Saleem; Ruheen Wali; Daria Plota; Wenjing Zhang; Sophie Schön; Soeren Brandenburg; Zhengyi Yang; Anna Steyer; Henning Urlaub; Torsten Rasmussen; Jens Mogensen; Julius Ryan D. Pronto; Yannic Döring; Michael H. Radke; Halyna Shcherbata; Stephan E. Lehnart; Andreas Janshoff; Samuel Sossalla; Torben Ruhwedel; Wiebke Moebius; Karl Toischer; Britta Brügger; Volker Haucke; Michael Gotthardt; Niels Voigt; Antje Ebert
errShare
errSave
RBM20 isoform regulation by independent transcription start sites adapts alternative splicing in development and disease
errNature Communications
IF15.7
err2026-05-23
err0
errOAAI
errMichael H. Radke; Victor Badillo Lisakowski; Stefan Meinke; Thiago Britto-Borges; Valentin Schneider-Lunitz; Oliver Hummel; Sebastiaan van Heesch; Jorge Ruiz Orera; Norbert Hubner; Henk Granzier; Christoph Dieterich; Michael Gotthardt
errShare
errSave
Alternative splicing dynamics during human cardiac development in vivo and in vitro
errStem Cell Reports
IF5.1
err2026-01-02
err0
errOAAI
errBeatriz Gomes-Silva; Marta Furtado; Marta Ribeiro; Sandra Martins; Teresa Carvalho; André Ventura-Gomes; Henrike Maatz; Pragati Parakkat; Claudia Crocini; Michael Gotthardt; Rosina Savisaar; Maria Carmo-Fonseca
errShare
errSave
Prime Editing Corrects The Dilated Cardiomyopathy Causing RBM20-P633L-Mutation in Human Cardiomyocytes
errMolecular Therapy Nucleic Acids
IF6.1
err2025-10-06
err0
errOAAI
errAlexandra Roman; Anja Zimmer; Michael Gotthardt; Lars M. Steinmetz; Ralf Kühn; Tu Dang
errShare
errSave
Rbm20 antisense oligonucleotides alleviate diastolic dysfunction in a mouse model of cardiometabolic heart failure (HFpEF)
errCARDIOVASCULAR RESEARCH
IF13.3
err2025-10-01
err0
PREAI
errMethawasin, Mei; Meinke, Stefan; Radke, Michael H.; Farman, Gerrie P.; Hourani, Zaynab; Smith III, John E.; Guo, Wei; Granzier, Henk; Gotthardt, Michael
errShare
errSave
Deep phenotyping of heart failure with preserved ejection fraction through multi-omics integration
errEuropean Journal of Heart Failure
IF10.8
err2025-09-22
err0
errOAAI
errJakob Versnjak; Titus Kuehne; Pauline Fahjen; Nina Jovanovic; Ulrike Löber; Gabriele G. Schiattarella; Nicola Wilck; Holger Gerhardt; Dominik N. Müller; Frank Edelmann; Philipp Mertins; Roland Eils; Michael Gotthardt; Sofia K. Forslund; Benjamin Wild; Marcus Kelm
errShare
errSave
Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies
errELIFE
IF0
err2024-12-17
err0
errOAAI
errHuettemeister, Judith; Rudolph, Franziska; Radke, Michael H.; Fink, Claudia; Friedrich, Dhana; Preibisch, Stephan; Falcke, Martin; Wagner, Eva; Lehnart, Stephan E.; Gotthardt, Michael
errShare
errSave
Titin's cardiac-specific N2B element is critical to mechanotransduction during volume overload of the heart
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2024-06-01
err3
errOAAI
errStrom, Joshua; Bull, Mathew; Gohlke, Jochen; Saripalli, Chandra; Methawasin, Mei; Gotthardt, Michael; Granzier, Henk
errShare
errSave
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction
errCARDIOVASCULAR RESEARCH
IF13.3
err2024-02-09
err1
errOAAI
errGotthardt, Michael; Lehnart, Stephan E.
errShare
errSave
Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation
errJACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
err2024-02-01
err7
errOAAI
errVad, Oliver B.; Angeli, Elisavet; Liss, Martin; Ahlberg, Gustav; Andreasen, Laura; Christophersen, Ingrid E.; Hansen, Camilla C.; Moller, Sophie; Hellsten, Ylva; Haunsoe, Stig; Tveit, Arnljot; Svendsen, Jesper H.; Gotthardt, Michael; Lundegaard, Pia R.; Olesen, Morten S.
errShare
errSave
Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3
errNATURE COMMUNICATIONS
IF15.7
err2023-07-18
err9
errOAAI
errKornienko, Julia; Rodriguez-Martinez, Marta; Fenzl, Kai; Hinze, Florian; Schraivogel, Daniel; Grosch, Markus; Tunaj, Brigit; Lindenhofer, Dominik; Schraft, Laura; Kueblbeck, Moritz; Smith, Eric; Mao, Chad; Brown, Emily; Owens, Anjali; Saguner, Ardan M. M.; Meder, Benjamin; Parikh, Victoria; Gotthardt, Michael; Steinmetz, Lars M. M.
errShare
errSave
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy
errNATURE COMMUNICATIONS
IF15.7
err2023-06-22
err16
errOAAI
errGrosch, Markus; Schraft, Laura; Chan, Adrian; Kuechenhoff, Leonie; Rapti, Kleopatra; Ferreira, Anne-Maud; Kornienko, Julia; Li, Shengdi; Radke, Michael H.; Kraemer, Chiara; Clauder-Muenster, Sandra; Perlas, Emerald; Backs, Johannes; Gotthardt, Michael; Dieterich, Christoph; van den Hoogenhof, Maarten M. G.; Grimm, Dirk; Steinmetz, Lars M.
errShare
errSave
CAR links hypoxia signaling to improved survival after myocardial infarction
errEXPERIMENTAL AND MOLECULAR MEDICINE
IF12.9
err2023-03-20
err1
errOAAI
errFreiberg, Fabian; Thakkar, Meghna; Hamann, Wiebke; Lopez Carballo, Jacobo; Juettner, Rene; Voss, Felizia K.; Becher, Peter M.; Westermann, Dirk; Tschoepe, Carsten; Heuser, Arnd; Rocks, Oliver; Fischer, Robert; Gotthardt, Michael
errShare
errSave
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
errMOLECULAR CELL
IF16.6
err2023-03-01
err46
errOAAI
errSandmann, Clara-L.; Schulz, Jana F.; Ruiz-Orera, Jorge; Kirchner, Marieluise; Ziehm, Matthias; Adami, Eleonora; Marczenke, Maike; Christ, Annabel; Liebe, Nina; Greiner, Johannes; Schoenenberger, Aaron; Muecke, Michael B.; Liang, Ning; Moritz, Robert L.; Sun, Zhi; Deutsch, Eric W.; Gotthardt, Michael; Mudge, Jonathan M.; Prensner, John R.; Willnow, Thomas E.; Mertins, Philipp; van Heesch, Sebastiaan; Hubner, Norbert
errShare
errSave
Disease- and sex-specific differences in patients with heart valve disease: a proteome study
errLIFE SCIENCE ALLIANCE
IF2.9
err2023-01-10
err3
errOAAI
errNordmeyer, Sarah; Kraus, Milena; Ziehm, Matthias; Kirchner, Marieluise; Schafstedde, Marie; Kelm, Marcus; Niquet, Sylvia; Stephen, Mariet Mathew; Baczko, Istvan; Knosalla, Christoph; Schapranow, Matthieu-P; Dittmar, Gunnar; Gotthardt, Michael; Falcke, Martin; Regitz-Zagrosek, Vera; Kuehne, Titus; Mertins, Philipp
errShare
errSave
A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2022-12-27
err9
errOAAI
errNeuschulz, Anika; Bakina, Olga; Badillo-Lisakowski, Victor; Olivares-Chauvet, Pedro; Conrad, Thomas; Gotthardt, Michael; Kettenmann, Helmut; Junker, Jan Philipp
errShare
errSave
The IgCAM CAR Regulates Gap Junction-Mediated Coupling on Embryonic Cardiomyocytes and Affects Their Beating Frequency
errLIFE-BASEL
IF3.4
err2022-12-21
err2
errOAAI
errMatthaeus, Claudia; Juettner, Rene; Gotthardt, Michael; Rathjen, Fritz G.
errShare
errSave
Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation
errNATURE COMMUNICATIONS
IF15.7
err2022-10-27
err8
errOAAI
errOrtiz-Zapater, Elena; Bagley, Dustin C.; Hernandez, Virginia Llopis; Roberts, Luke B.; Maguire, Thomas J. A.; Voss, Felizia; Mertins, Philipp; Kirchner, Marieluise; Peset-Martin, Isabel; Woszczek, Grzegorz; Rosenblatt, Jody; Gotthardt, Michael; Santis, George; Parsons, Maddy
errShare
errSave
Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20
errMOLECULAR CELL
IF16.6
err2022-06-01
err13
errOAAI
errVieira-Vieira, Carlos Henrique; Dauksaite, Vita; Sporbert, Anje; Gotthardt, Michael; Selbach, Matthias
errShare
errSave
HDAC6 modulates myofibril stiffness and diastolic function of the heart
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-05-16
err23
errOAAI
errLin, Ying-Hsi; Major, Jennifer L.; Liebner, Tim; Hourani, Zaynab; Travers, Joshua G.; Wennersten, Sara A.; Haefner, Korey R.; Cavasin, Maria A.; Wilson, Cortney E.; Jeong, Mark Y.; Han, Yu; Gotthardt, Michael; Ferguson, Scott K.; Ambardekar, Amrut, V; Lam, Maggie P. Y.; Choudhary, Chunaram; Granzier, Henk L.; Woulfe, Kathleen C.; McKinsey, Timothy A.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
S
Stacey Gabriel
H-index: 220 · Papers: 938
M
M Snyder
H-index: 210 · Papers: 3.3K
B
Bradley T. Hyman
H-index: 187 · Papers: 1.1K
C
Colin L. Masters
H-index: 172 · Papers: 2.1K
C
Christian Weber
H-index: 160 · Papers: 1.8K
View more